(30 nodes) Response to interleukin-1 network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (592 aa)
	LOC101073756	Ribosomal protein S6 kinase. (800 aa)
	LOC101064039	A kinase (PRKA) anchor protein 12b. (1437 aa)
	YTHDC2	YTH domain containing 2. (1374 aa)
	ENSTRUP00000077609	Uncharacterized protein. (489 aa)
	LOC101078142	Ribosomal protein S6 kinase. (811 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1095 aa)
	tnip2	TNFAIP3 interacting protein 2. (479 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (880 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (772 aa)
	LOC101073524	Tumor necrosis factor receptor superfamily member 11A isoform X2. (640 aa)
	LOC101061975	Chemokine (C-C motif) ligand 25b. (100 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (146 aa)
	LOC101065036	SCY domain-containing protein. (100 aa)
	tank	TBD domain-containing protein. (361 aa)
	ccl19	SCY domain-containing protein. (113 aa)
	LOC101064358	Chemokine (C-C motif) ligand 25a. (102 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
	il1b	Interleukin-1; Belongs to the IL-1 family. (256 aa)
	H2UQS6_TAKRU	Uncharacterized protein. (516 aa)
	LOC101065338	Uncharacterized protein. (637 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (608 aa)
	acod1	Aconitate decarboxylase 1. (479 aa)
	zc3h12a	Si:dkey-206d17.12. (176 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1123 aa)
	cd40	CD40. (307 aa)
	LOC101061773	Interleukin-1 receptor-associated kinase 1. (721 aa)
	rbmx	RNA binding motif protein X-linked. (391 aa)
	LOC101078749	Nuclear receptor subfamily 1, group D, member 4a. (574 aa)
	H2SAI0_TAKRU	Receptor-interacting serine-threonine kinase 2. (554 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000077609	acod1	ENSTRUP00000077609	ENSTRUP00000026668	Uncharacterized protein.	Aconitate decarboxylase 1.	0.902
H2SAI0_TAKRU	LOC101061773	ENSTRUP00000009406	ENSTRUP00000016336	Receptor-interacting serine-threonine kinase 2.	Interleukin-1 receptor-associated kinase 1.	0.630
H2SAI0_TAKRU	il1b	ENSTRUP00000009406	ENSTRUP00000040920	Receptor-interacting serine-threonine kinase 2.	Interleukin-1; Belongs to the IL-1 family.	0.433
H2SAI0_TAKRU	traf6	ENSTRUP00000009406	ENSTRUP00000041697	Receptor-interacting serine-threonine kinase 2.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.861
H2UQS6_TAKRU	LOC101061773	ENSTRUP00000039299	ENSTRUP00000016336	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 1.	0.797
H2UQS6_TAKRU	il1b	ENSTRUP00000039299	ENSTRUP00000040920	Uncharacterized protein.	Interleukin-1; Belongs to the IL-1 family.	0.907
H2UQS6_TAKRU	traf6	ENSTRUP00000039299	ENSTRUP00000041697	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.802
LOC101061773	H2SAI0_TAKRU	ENSTRUP00000016336	ENSTRUP00000009406	Interleukin-1 receptor-associated kinase 1.	Receptor-interacting serine-threonine kinase 2.	0.630
LOC101061773	H2UQS6_TAKRU	ENSTRUP00000016336	ENSTRUP00000039299	Interleukin-1 receptor-associated kinase 1.	Uncharacterized protein.	0.797
LOC101061773	LOC101065338	ENSTRUP00000016336	ENSTRUP00000039107	Interleukin-1 receptor-associated kinase 1.	Uncharacterized protein.	0.797
LOC101061773	il1b	ENSTRUP00000016336	ENSTRUP00000040920	Interleukin-1 receptor-associated kinase 1.	Interleukin-1; Belongs to the IL-1 family.	0.799
LOC101061773	traf6	ENSTRUP00000016336	ENSTRUP00000041697	Interleukin-1 receptor-associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
LOC101061975	LOC101065036	ENSTRUP00000056274	ENSTRUP00000054825	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.579
LOC101061975	ccl19	ENSTRUP00000056274	ENSTRUP00000050152	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.710
LOC101064358	LOC101065036	ENSTRUP00000047928	ENSTRUP00000054825	Chemokine (C-C motif) ligand 25a.	SCY domain-containing protein.	0.579
LOC101064358	ccl19	ENSTRUP00000047928	ENSTRUP00000050152	Chemokine (C-C motif) ligand 25a.	SCY domain-containing protein.	0.814
LOC101065036	LOC101061975	ENSTRUP00000054825	ENSTRUP00000056274	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.579
LOC101065036	LOC101064358	ENSTRUP00000054825	ENSTRUP00000047928	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25a.	0.579
LOC101065338	LOC101061773	ENSTRUP00000039107	ENSTRUP00000016336	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 1.	0.797
LOC101065338	il1b	ENSTRUP00000039107	ENSTRUP00000040920	Uncharacterized protein.	Interleukin-1; Belongs to the IL-1 family.	0.941