STRINGSTRING
wnt11 wnt11 Tnn Tnn TLE4 TLE4 LOC101062691 LOC101062691 cyld cyld LOC115251758 LOC115251758 ENSTRUP00000083198 ENSTRUP00000083198 gsk3b gsk3b tmem131l tmem131l TLE3 TLE3 apoe2 apoe2 ENSTRUP00000073129 ENSTRUP00000073129 LOC101066916 LOC101066916 ENSTRUP00000071540 ENSTRUP00000071540 rspo3 rspo3 ENSTRUP00000069997 ENSTRUP00000069997 H2RRN3_TAKRU H2RRN3_TAKRU LOC101078578 LOC101078578 ENSTRUP00000067289 ENSTRUP00000067289 LOC101064354 LOC101064354 znrf3 znrf3 H2SQ70_TAKRU H2SQ70_TAKRU sox13 sox13 LOC101062197 LOC101062197 LOC105418777 LOC105418777 prkn prkn sfrp2 sfrp2 ankrd6 ankrd6 H2UNW5_TAKRU H2UNW5_TAKRU nkd2 nkd2 LOC101062949 LOC101062949 csnk1a1 csnk1a1 LOC101065642 LOC101065642 tmem170b tmem170b LOC101073080 LOC101073080 lats2 lats2 shisa3 shisa3 LOC101061964 LOC101061964 LOC101078865 LOC101078865 ENSTRUP00000051366 ENSTRUP00000051366 lzts2 lzts2 cthrc1 cthrc1 LOC101063744 LOC101063744 ENSTRUP00000050110 ENSTRUP00000050110 ddit3 ddit3 dkk2 dkk2 ENSTRUP00000049640 ENSTRUP00000049640 sfrp5 sfrp5 Tpbg Tpbg LOC101075057 LOC101075057 LOC101077877 LOC101077877 dab2 dab2 grem1 grem1 LOC101067938 LOC101067938 cby1 cby1 ENSTRUP00000043529 ENSTRUP00000043529 LOC101072553 LOC101072553 H2UXJ7_TAKRU H2UXJ7_TAKRU H2UXJ1_TAKRU H2UXJ1_TAKRU kremen1 kremen1 LOC101075840 LOC101075840 LOC101068534 LOC101068534 frzb frzb scyl2 scyl2 H2U9Y0_TAKRU H2U9Y0_TAKRU axin1 axin1 LOC101075662 LOC101075662 LOC101062420 LOC101062420 lmbr1l lmbr1l apoe1 apoe1 LOC101061589 LOC101061589 LOC101077870 LOC101077870 nkx2-5 nkx2-5 LOC105416356 LOC105416356 apc apc lmbr1 lmbr1 stk11 stk11 vangl2 vangl2 ubac2 ubac2 bicc1 bicc1 nkd1 nkd1 LOC101064580 LOC101064580 pfdn5 pfdn5 LOC101075674 LOC101075674 wnt8 wnt8 CHD8 CHD8 fzd4 fzd4 AXIN2 AXIN2 LOC101065974 LOC101065974 sfrp1 sfrp1 LOC101065819 LOC101065819 LOC101074197 LOC101074197 LOC101080164 LOC101080164 lats1 lats1 LOC101074648 LOC101074648 igfbp6 igfbp6 LOC101068730 LOC101068730 ENSTRUP00000000520 ENSTRUP00000000520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TnnFibronectin type-III domain-containing protein. (1119 aa)
TLE4Uncharacterized protein. (784 aa)
LOC101062691Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (469 aa)
cyldCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (980 aa)
LOC115251758Transmembrane protein 64-like. (352 aa)
ENSTRUP00000083198Leucine zipper putative tumor suppressor 3. (995 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (459 aa)
tmem131lTransmembrane protein 131-like isoform X2. (1540 aa)
TLE3Transducin-like enhancer protein 3. (835 aa)
apoe2Apolipoprotein E2. (276 aa)
ENSTRUP00000073129annotation not available (969 aa)
LOC101066916Cylindromatosis (turban tumor syndrome), like. (690 aa)
ENSTRUP00000071540FERM domain containing 8. (310 aa)
rspo3R-spondin 3. (327 aa)
ENSTRUP00000069997annotation not available (312 aa)
H2RRN3_TAKRUAPC membrane recruitment protein 2. (623 aa)
LOC101078578Uncharacterized protein. (768 aa)
ENSTRUP00000067289annotation not available (215 aa)
LOC101064354TLE family member 2, transcriptional corepressor b. (765 aa)
znrf3Zinc and ring finger 3. (919 aa)
H2SQ70_TAKRUUncharacterized protein. (270 aa)
sox13SRY-box transcription factor 13. (637 aa)
LOC101062197Uncharacterized protein. (491 aa)
LOC105418777Usher syndrome type-1C protein-binding protein 1. (674 aa)
prknUbiquitin-like domain-containing protein. (532 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
ankrd6Ankyrin repeat domain-containing protein 6. (749 aa)
H2UNW5_TAKRUTLE family member 3, transcriptional corepressor. (802 aa)
nkd2NKD inhibitor of WNT signaling pathway 2a. (509 aa)
LOC101062949Adenomatous polyposis coli protein 2-like isoform X1. (2486 aa)
csnk1a1Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (365 aa)
LOC101065642TLE family member 5, transcriptional modulator. (213 aa)
tmem170bTransmembrane protein 170B. (130 aa)
LOC101073080Uncharacterized protein. (350 aa)
lats2Large tumor suppressor kinase 2. (1182 aa)
shisa3Shisa family member 3. (282 aa)
LOC101061964Dishevelled-binding antagonist of beta-catenin 3a. (676 aa)
LOC101078865Cylindromatosis (turban tumor syndrome), b. (689 aa)
ENSTRUP00000051366Mesoderm posterior aa. (214 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (685 aa)
cthrc1Collagen triple helix repeat containing 1b. (228 aa)
LOC101063744APC membrane recruitment protein 1. (819 aa)
ENSTRUP00000050110Uncharacterized protein. (591 aa)
ddit3DNA-damage-inducible transcript 3. (309 aa)
dkk2Dickkopf WNT signaling pathway inhibitor 2. (245 aa)
ENSTRUP00000049640Mesoderm posterior ba. (223 aa)
sfrp5Secreted frizzled-related protein 5. (321 aa)
TpbgTrophoblast glycoprotein. (392 aa)
LOC101075057Dickkopf_N domain-containing protein. (302 aa)
LOC101077877Transmembrane protein 88 a. (196 aa)
dab2DAB adaptor protein 2. (759 aa)
grem1Gremlin 1a, DAN family BMP antagonist. (176 aa)
LOC101067938Dickkopf WNT signaling pathway inhibitor 3a. (254 aa)
cby1Chibby homolog 1 (Drosophila). (130 aa)
ENSTRUP00000043529annotation not available (84 aa)
LOC101072553Sizzled. (283 aa)
H2UXJ7_TAKRUAxin 2 (conductin, axil). (336 aa)
H2UXJ1_TAKRUDIX domain-containing protein. (257 aa)
kremen1Kringle containing transmembrane protein 1. (472 aa)
LOC101075840Uncharacterized protein. (882 aa)
LOC101068534Transmembrane protein 64. (352 aa)
frzbFrizzled related protein. (439 aa)
scyl2SCY1 like pseudokinase 2. (929 aa)
H2U9Y0_TAKRUUncharacterized protein. (366 aa)
axin1Axin 1. (833 aa)
LOC101075662Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (777 aa)
LOC101062420Notum, palmitoleoyl-protein carboxylesterase. (462 aa)
lmbr1lLimb development membrane protein 1-like; Belongs to the LIMR family. (496 aa)
apoe1Uncharacterized protein. (247 aa)
LOC101061589Notum pectinacetylesterase 2. (484 aa)
LOC101077870Bicaudal C homolog 2. (909 aa)
nkx2-5NK2 homeobox 5. (324 aa)
LOC105416356Dickkopf WNT signaling pathway inhibitor 1a. (348 aa)
apcAPC regulator of WNT signaling pathway. (2226 aa)
lmbr1Limb development membrane protein 1; Belongs to the LIMR family. (492 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
vangl2Vang-like protein. (525 aa)
ubac2UBA domain containing 2. (353 aa)
bicc1BicC family RNA binding protein 1a. (970 aa)
nkd1NKD inhibitor of WNT signaling pathway 1. (445 aa)
LOC101064580TLE family member 2, transcriptional corepressor a. (804 aa)
pfdn5Prefoldin 5. (154 aa)
LOC101075674Uncharacterized protein. (263 aa)
wnt8Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2507 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
AXIN2Axin 2. (790 aa)
LOC101065974Uncharacterized protein. (244 aa)
sfrp1Secreted frizzled-related protein 1a. (307 aa)
LOC101065819Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (449 aa)
LOC101074197Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (581 aa)
LOC101080164Trophoblast glycoprotein a. (362 aa)
lats1Large tumor suppressor kinase 1. (1079 aa)
LOC101074648FERM domain containing 8. (466 aa)
igfbp6Insulin-like growth factor binding protein 6b. (201 aa)
LOC101068730VANGL planar cell polarity protein 2. (525 aa)
ENSTRUP00000000520Ubiquitin carboxyl-terminal hydrolase CYLD-like. (668 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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