STRINGSTRING
LOC101069879 LOC101069879 hspa5 hspa5 amfr amfr nbn nbn rpn1 rpn1 ormdl1 ormdl1 emc8 emc8 pigk pigk ern1 ern1 spcs1 spcs1 LOC101066134 LOC101066134 emc1 emc1 rpn2 rpn2 zw10 zw10 syvn1 syvn1 ganab ganab emc7 emc7 LOC115251968 LOC115251968 dad1 dad1 emc10 emc10 H2RPX4_TAKRU H2RPX4_TAKRU pigq pigq faf1 faf1 ddost ddost LOC115248283 LOC115248283 rnf139 rnf139 hyou1 hyou1 stt3a stt3a spcs3 spcs3 emc4 emc4 ubxn7 ubxn7 fam167a fam167a pdia4 pdia4 sptssb sptssb ostc ostc LOC101078521 LOC101078521 LOC101077331 LOC101077331 get3 get3 srpra srpra abcb9 abcb9 pigu pigu aup1 aup1 camlg camlg SEC61A1 SEC61A1 LOC101075256 LOC101075256 LOC101071039 LOC101071039 LOC101070568 LOC101070568 gpaa1 gpaa1 piga piga faf2 faf2 Sec61b Sec61b sptlc1 sptlc1 rint1 rint1 Dpm2 Dpm2 sel1l sel1l insig2 insig2 LOC101067335 LOC101067335 pdia3 pdia3 nbas nbas LOC101063622 LOC101063622 emc9 emc9 vcp vcp derl2 derl2 ost4 ost4 insig1 insig1 ormdl2 ormdl2 pigh pigh krtcap2 krtcap2 ppib ppib tapbp tapbp pigt pigt LOC101075371 LOC101075371 pigc pigc ufd1 ufd1 mmgt1 mmgt1 LOC101067048 LOC101067048 H2SB48_TAKRU H2SB48_TAKRU PIGM PIGM UBXN7 UBXN7 hm13 hm13 Tmem258 Tmem258 ENSTRUP00000068490 ENSTRUP00000068490 LOC101066072 LOC101066072 ENSTRUP00000077339 ENSTRUP00000077339 ext2 ext2 ENSTRUP00000075769 ENSTRUP00000075769 map3k5 map3k5 emc3 emc3 ENSTRUP00000074317 ENSTRUP00000074317 ENSTRUP00000073419 ENSTRUP00000073419 pigs pigs LOC101076802 LOC101076802 selenos selenos alg14 alg14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101069879ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (660 aa)
amfrAutocrine motility factor receptor b. (645 aa)
nbnNibrin. (831 aa)
rpn1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (603 aa)
ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
emc8ER membrane protein complex subunit 8. (204 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (395 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1017 aa)
spcs1Signal peptidase complex subunit 1. (102 aa)
LOC101066134Magnesium transporter 1. (331 aa)
emc1ER membrane protein complex subunit 1. (994 aa)
rpn2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (643 aa)
zw10Zw10 kinetochore protein. (781 aa)
syvn1Synovial apoptosis inhibitor 1, synoviolin. (625 aa)
ganabGlucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (950 aa)
emc7ER membrane protein complex subunit 7. (276 aa)
LOC115251968Selenoprotein S-like. (154 aa)
dad1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
emc10ER membrane protein complex subunit 10. (256 aa)
H2RPX4_TAKRUER membrane protein complex subunit 6. (110 aa)
pigqPhosphatidylinositol glycan anchor biosynthesis, class Q. (598 aa)
faf1Fas (TNFRSF6) associated factor 1. (669 aa)
ddostDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (465 aa)
LOC115248283GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (411 aa)
rnf139Ring finger protein 139. (702 aa)
hyou1Hypoxia up-regulated 1. (975 aa)
stt3aSTT3 oligosaccharyltransferase complex catalytic subunit A. (743 aa)
spcs3Signal peptidase complex subunit 3. (180 aa)
emc4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (196 aa)
ubxn7UBX domain protein 7. (558 aa)
fam167aFamily with sequence similarity 167 member Ab. (155 aa)
pdia4Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (636 aa)
sptssbSerine palmitoyltransferase, small subunit B. (80 aa)
ostcOligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (151 aa)
LOC101078521ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
LOC101077331Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (718 aa)
get3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
srpraSRP receptor subunit alpha. (650 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (796 aa)
piguPhosphatidylinositol glycan anchor biosynthesis, class U. (465 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (411 aa)
camlgCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (263 aa)
SEC61A1Plug_translocon domain-containing protein. (476 aa)
LOC101075256Plug_translocon domain-containing protein. (489 aa)
LOC101071039Si:ch211-1i11.3. (1324 aa)
LOC101070568Transporter associated with antigen processing, subunit type t, teleost specific. (729 aa)
gpaa1Glycosylphosphatidylinositol anchor attachment 1. (600 aa)
pigaPhosphatidylinositol glycan anchor biosynthesis, class A. (487 aa)
faf2Fas associated factor family member 2. (445 aa)
Sec61bUncharacterized protein. (103 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (473 aa)
rint1RAD50 interactor 1. (780 aa)
Dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa)
sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (823 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (207 aa)
LOC101067335Family with sequence similarity 8 member A1a. (356 aa)
pdia3Protein disulfide-isomerase. (498 aa)
nbasNeuroblastoma amplified sequence. (2351 aa)
LOC101063622Tumor suppressor candidate 3. (340 aa)
emc9ER membrane protein complex subunit 9. (205 aa)
vcpValosin containing protein; Belongs to the AAA ATPase family. (819 aa)
derl2Derlin-2/3. (239 aa)
ost4Oligosaccharyltransferase complex subunit 4 (non-catalytic). (37 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (272 aa)
ormdl2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
pighPhosphatidylinositol glycan anchor biosynthesis, class H. (180 aa)
krtcap2Keratinocyte associated protein 2. (178 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
tapbpTAP binding protein (tapasin), tandem duplicate 2. (466 aa)
pigtPhosphatidylinositol glycan anchor biosynthesis, class T. (643 aa)
LOC101075371Family with sequence similarity 8 member A1b. (346 aa)
pigcPhosphatidylinositol glycan anchor biosynthesis, class C. (329 aa)
ufd1Ubiquitin recognition factor in ER associated degradation 1. (400 aa)
mmgt1Membrane magnesium transporter 1. (130 aa)
LOC101067048Endoplasmic reticulum to nucleus signaling 2. (1011 aa)
H2SB48_TAKRUSerine palmitoyltransferase, small subunit A. (68 aa)
PIGMPhosphatidylinositol glycan anchor biosynthesis class M. (394 aa)
UBXN7UBX domain protein 7. (521 aa)
hm13Histocompatibility (minor) 13. (417 aa)
Tmem258Transmembrane protein 258. (74 aa)
ENSTRUP00000068490Uncharacterized protein. (1027 aa)
LOC101066072Transporter associated with antigen processing, subunit type a. (721 aa)
ENSTRUP00000077339Selenoprotein S. (214 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (747 aa)
ENSTRUP00000075769Signal peptidase complex subunit 2. (144 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1350 aa)
emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
ENSTRUP00000074317ER membrane protein complex subunit 10. (226 aa)
ENSTRUP00000073419annotation not available (350 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (574 aa)
LOC101076802STT3 oligosaccharyltransferase complex catalytic subunit B. (811 aa)
selenosSelenoprotein S. (174 aa)
alg14ALG14 UDP-N-acetylglucosaminyltransferase subunit. (214 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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