(8 nodes) Regulation of T-helper 17 cell differentiation network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rc3h2	Ring finger and CCCH-type domains 2. (1042 aa)
	LOC101069090	MALT paracaspase 2. (816 aa)
	malt1	MALT paracaspase 1. (836 aa)
	tbx21	T-box transcription factor 21. (616 aa)
	nfkbid	ANK_REP_REGION domain-containing protein. (472 aa)
	zc3h12a	Si:dkey-206d17.12. (176 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1123 aa)
	LOC105416219	MALT paracaspase 3. (589 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101069090	LOC105416219	ENSTRUP00000076686	ENSTRUP00000010990	MALT paracaspase 2.	MALT paracaspase 3.	0.906
LOC101069090	malt1	ENSTRUP00000076686	ENSTRUP00000077782	MALT paracaspase 2.	MALT paracaspase 1.	0.903
LOC105416219	LOC101069090	ENSTRUP00000010990	ENSTRUP00000076686	MALT paracaspase 3.	MALT paracaspase 2.	0.906
LOC105416219	malt1	ENSTRUP00000010990	ENSTRUP00000077782	MALT paracaspase 3.	MALT paracaspase 1.	0.902
Rc3h2	rc3h1	ENSTRUP00000007866	ENSTRUP00000020897	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.646
malt1	LOC101069090	ENSTRUP00000077782	ENSTRUP00000076686	MALT paracaspase 1.	MALT paracaspase 2.	0.903
malt1	LOC105416219	ENSTRUP00000077782	ENSTRUP00000010990	MALT paracaspase 1.	MALT paracaspase 3.	0.902
rc3h1	Rc3h2	ENSTRUP00000020897	ENSTRUP00000007866	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.646
rc3h1	zc3h12a	ENSTRUP00000020897	ENSTRUP00000026666	Ring finger and CCCH-type domains 1b.	Si:dkey-206d17.12.	0.565
zc3h12a	rc3h1	ENSTRUP00000026666	ENSTRUP00000020897	Si:dkey-206d17.12.	Ring finger and CCCH-type domains 1b.	0.565