60 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSTRUP00000054856	CASP2 and RIPK1 domain containing adaptor with death domain. (114 aa)
	ENSTRUP00000000520	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (668 aa)
	LOC101079861	Nuclear protein 1b. (76 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (669 aa)
	ptprc	Uncharacterized protein. (1248 aa)
	skil	SKI-like proto-oncogene a. (783 aa)
	pea15	Proliferation and apoptosis adaptor protein 15. (130 aa)
	LOC101074499	BRICHOS domain-containing protein. (257 aa)
	eef1e1	Eukaryotic translation elongation factor 1 epsilon 1. (235 aa)
	LOC101073138	Uncharacterized protein. (311 aa)
	ctsc	Cathepsin C; Belongs to the peptidase C1 family. (462 aa)
	LOC101068989	Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family. (414 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (422 aa)
	rbck1	RanBP-type and C3HC4-type zinc finger containing 1. (517 aa)
	traf7	TNF receptor-associated factor 7. (661 aa)
	nck2	Cytoplasmic protein. (396 aa)
	LOC101067094	Muscle segment homeobox 3. (253 aa)
	PAK2	Non-specific serine/threonine protein kinase. (547 aa)
	LOC101067572	Uncharacterized protein. (589 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (449 aa)
	gsdme	Gasdermin Eb. (460 aa)
	msx1	Homeobox domain-containing protein. (283 aa)
	nck1	Cytoplasmic protein. (399 aa)
	sirt1	Sirtuin 1. (689 aa)
	inhbb	Inhibin subunit beta B. (402 aa)
	G0S2	Uncharacterized protein. (120 aa)
	ddit3	DNA-damage-inducible transcript 3. (309 aa)
	LOC101065591	Uncharacterized protein. (474 aa)
	dedd2	Death effector domain-containing 1. (388 aa)
	bax	BCL2 associated X, apoptosis regulator a. (193 aa)
	LOC101078865	Cylindromatosis (turban tumor syndrome), b. (689 aa)
	timp3	NTR domain-containing protein. (214 aa)
	ENSTRUP00000055562	Uncharacterized protein. (55 aa)
	ENSTRUP00000055918	Uncharacterized protein. (287 aa)
	ENSTRUP00000056963	annotation not available (197 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (350 aa)
	LOC101067067	DED domain-containing protein. (196 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	ENSTRUP00000065235	annotation not available (381 aa)
	nfatc4	Uncharacterized protein. (893 aa)
	ENSTRUP00000066347	Tumor necrosis factor receptor superfamily member 5-like. (283 aa)
	INHBB	TGF_BETA_2 domain-containing protein. (408 aa)
	LOC101078053	Integral membrane protein 2Cb. (256 aa)
	flcn	Folliculin. (565 aa)
	tp73	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (670 aa)
	LOC101063970	Activating transcription factor 3. (216 aa)
	LOC101066916	Cylindromatosis (turban tumor syndrome), like. (690 aa)
	ENSTRUP00000073129	annotation not available (969 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (619 aa)
	LOC101063970-2	Cyclic AMP-dependent transcription factor ATF-3. (216 aa)
	tp63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (668 aa)
	tpd52l1	Tpd52 like 1. (243 aa)
	LOC101078548	Mitogen-activated protein kinase. (456 aa)
	LOC105418743	BCL2 associated agonist of cell death b. (168 aa)
	LOC115248024	Integral membrane protein 2C-like. (256 aa)
	srpx	Sushi-repeat containing protein X-linked. (470 aa)
	ENSTRUP00000082979	Inhibin beta A chain-like. (390 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (980 aa)
	LOC101073973	TGF_BETA_2 domain-containing protein. (421 aa)
	tnfsf10	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (319 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000000520	ENSTRUP00000056963	ENSTRUP00000000520	ENSTRUP00000056963	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	annotation not available	0.491
ENSTRUP00000000520	LOC101067067	ENSTRUP00000000520	ENSTRUP00000061734	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	DED domain-containing protein.	0.491
ENSTRUP00000000520	LOC101078865	ENSTRUP00000000520	ENSTRUP00000052763	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	Cylindromatosis (turban tumor syndrome), b.	0.907
ENSTRUP00000000520	cyld	ENSTRUP00000000520	ENSTRUP00000083915	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.905
ENSTRUP00000000520	rbck1	ENSTRUP00000000520	ENSTRUP00000029671	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	RanBP-type and C3HC4-type zinc finger containing 1.	0.504
ENSTRUP00000054856	ENSTRUP00000056963	ENSTRUP00000054856	ENSTRUP00000056963	CASP2 and RIPK1 domain containing adaptor with death domain.	annotation not available	0.527
ENSTRUP00000054856	LOC101067067	ENSTRUP00000054856	ENSTRUP00000061734	CASP2 and RIPK1 domain containing adaptor with death domain.	DED domain-containing protein.	0.527
ENSTRUP00000054856	casp2	ENSTRUP00000054856	ENSTRUP00000037606	CASP2 and RIPK1 domain containing adaptor with death domain.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.953
ENSTRUP00000055918	ENSTRUP00000056963	ENSTRUP00000055918	ENSTRUP00000056963	Uncharacterized protein.	annotation not available	0.963
ENSTRUP00000055918	LOC101067067	ENSTRUP00000055918	ENSTRUP00000061734	Uncharacterized protein.	DED domain-containing protein.	0.963
ENSTRUP00000055918	casp2	ENSTRUP00000055918	ENSTRUP00000037606	Uncharacterized protein.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.556
ENSTRUP00000055918	faf1	ENSTRUP00000055918	ENSTRUP00000004343	Uncharacterized protein.	Fas (TNFRSF6) associated factor 1.	0.690
ENSTRUP00000055918	ptprc	ENSTRUP00000055918	ENSTRUP00000005791	Uncharacterized protein.	Uncharacterized protein.	0.498
ENSTRUP00000055918	tnfsf10	ENSTRUP00000055918	ENSTRUP00000088355	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.805
ENSTRUP00000056963	ENSTRUP00000000520	ENSTRUP00000056963	ENSTRUP00000000520	annotation not available	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	0.491
ENSTRUP00000056963	ENSTRUP00000054856	ENSTRUP00000056963	ENSTRUP00000054856	annotation not available	CASP2 and RIPK1 domain containing adaptor with death domain.	0.527
ENSTRUP00000056963	ENSTRUP00000055918	ENSTRUP00000056963	ENSTRUP00000055918	annotation not available	Uncharacterized protein.	0.963
ENSTRUP00000056963	ENSTRUP00000073129	ENSTRUP00000056963	ENSTRUP00000073129	annotation not available	annotation not available	0.477
ENSTRUP00000056963	LOC101066916	ENSTRUP00000056963	ENSTRUP00000071560	annotation not available	Cylindromatosis (turban tumor syndrome), like.	0.491
ENSTRUP00000056963	LOC101078865	ENSTRUP00000056963	ENSTRUP00000052763	annotation not available	Cylindromatosis (turban tumor syndrome), b.	0.491