(20 nodes) CRIB domain network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105418661	Non-specific serine/threonine protein kinase. (609 aa)
	pak1	Non-specific serine/threonine protein kinase. (562 aa)
	cdc42se1	CDC42 small effector 1. (75 aa)
	cdc42bpa	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1837 aa)
	LOC101077494	Zgc:154093. (320 aa)
	pak4	Non-specific serine/threonine protein kinase. (664 aa)
	pak5	Non-specific serine/threonine protein kinase. (742 aa)
	LOC105416413	CDC42 effector protein (Rho GTPase binding) 1b. (357 aa)
	PAK2	Non-specific serine/threonine protein kinase. (547 aa)
	LOC101071646	Uncharacterized protein. (545 aa)
	wasl	WASP like actin nucleation promoting factor a. (527 aa)
	LOC101069458	WASP like actin nucleation promoting factor b. (505 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	LOC105418134	CRIB domain-containing protein. (183 aa)
	LOC101073130	CDC42 effector protein (Rho GTPase binding) 4a. (345 aa)
	cdc42se2	CDC42 small effector 2. (76 aa)
	LOC105416571	CDC42 effector protein (Rho GTPase binding) 1a. (426 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	LOC101076479	Non-specific serine/threonine protein kinase. (722 aa)
	cdc42bpb	Non-specific serine/threonine protein kinase. (1777 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101069458	PAK2	ENSTRUP00000042543	ENSTRUP00000036768	WASP like actin nucleation promoting factor b.	Non-specific serine/threonine protein kinase.	0.420
LOC101069458	PAK3	ENSTRUP00000042543	ENSTRUP00000042993	WASP like actin nucleation promoting factor b.	Non-specific serine/threonine protein kinase.	0.407
LOC101069458	pak1	ENSTRUP00000042543	ENSTRUP00000011910	WASP like actin nucleation promoting factor b.	Non-specific serine/threonine protein kinase.	0.407
LOC101069458	pak2	ENSTRUP00000042543	ENSTRUP00000063452	WASP like actin nucleation promoting factor b.	Non-specific serine/threonine protein kinase.	0.420
LOC101071646	PAK2	ENSTRUP00000040271	ENSTRUP00000036768	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.420
LOC101071646	PAK3	ENSTRUP00000040271	ENSTRUP00000042993	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.407
LOC101071646	pak1	ENSTRUP00000040271	ENSTRUP00000011910	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.585
LOC101071646	pak2	ENSTRUP00000040271	ENSTRUP00000063452	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.420
LOC101073130	LOC101077494	ENSTRUP00000049802	ENSTRUP00000019403	CDC42 effector protein (Rho GTPase binding) 4a.	Zgc:154093.	0.466
LOC101073130	cdc42se1	ENSTRUP00000049802	ENSTRUP00000011933	CDC42 effector protein (Rho GTPase binding) 4a.	CDC42 small effector 1.	0.572
LOC101073130	cdc42se2	ENSTRUP00000049802	ENSTRUP00000056272	CDC42 effector protein (Rho GTPase binding) 4a.	CDC42 small effector 2.	0.566
LOC101076479	PAK2	ENSTRUP00000064836	ENSTRUP00000036768	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.408
LOC101076479	PAK3	ENSTRUP00000064836	ENSTRUP00000042993	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.404
LOC101076479	pak1	ENSTRUP00000064836	ENSTRUP00000011910	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.404
LOC101076479	pak2	ENSTRUP00000064836	ENSTRUP00000063452	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.405
LOC101077494	LOC101073130	ENSTRUP00000019403	ENSTRUP00000049802	Zgc:154093.	CDC42 effector protein (Rho GTPase binding) 4a.	0.466
LOC101077494	LOC105416413	ENSTRUP00000019403	ENSTRUP00000026992	Zgc:154093.	CDC42 effector protein (Rho GTPase binding) 1b.	0.466
LOC105416413	LOC101077494	ENSTRUP00000026992	ENSTRUP00000019403	CDC42 effector protein (Rho GTPase binding) 1b.	Zgc:154093.	0.466
LOC105418661	PAK2	ENSTRUP00000010568	ENSTRUP00000036768	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.416
LOC105418661	PAK3	ENSTRUP00000010568	ENSTRUP00000042993	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.409