(20 nodes) Hemopexin-like domain network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101074710	Matrix metallopeptidase 15a. (698 aa)
	LOC101069093	Matrix metallopeptidase 16b (membrane-inserted). (612 aa)
	mmp14	Matrix metallopeptidase 14a (membrane-inserted). (562 aa)
	wap65-2	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (449 aa)
	mmp2	Matrix metalloproteinase-2. (663 aa)
	mmp9	Uncharacterized protein. (631 aa)
	mmpf1	Matrix metalloproteinase. (474 aa)
	H2SI73_TAKRU	ZnMc domain-containing protein. (578 aa)
	LOC101075365	ZnMc domain-containing protein. (474 aa)
	LOC101079398	Matrix metallopeptidase 11a. (481 aa)
	hpx	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (425 aa)
	LOC101063214	Vitronectin a. (535 aa)
	mmp28	PG_binding_1 domain-containing protein. (518 aa)
	LOC101070441	Matrix metallopeptidase 16. (658 aa)
	LOC101061607	Matrix metallopeptidase 14b (membrane-inserted). (630 aa)
	LOC101063812	Vitronectin b. (468 aa)
	prg4	Proteoglycan 4b. (637 aa)
	mmp13	Matrix metalloproteinase. (461 aa)
	LOC101080029	Matrix metallopeptidase 25b. (570 aa)
	LOC101071448	Matrix metallopeptidase 15b. (657 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2SI73_TAKRU	LOC101061607	ENSTRUP00000012101	ENSTRUP00000062505	ZnMc domain-containing protein.	Matrix metallopeptidase 14b (membrane-inserted).	0.564
H2SI73_TAKRU	LOC101069093	ENSTRUP00000012101	ENSTRUP00000073448	ZnMc domain-containing protein.	Matrix metallopeptidase 16b (membrane-inserted).	0.465
H2SI73_TAKRU	LOC101070441	ENSTRUP00000012101	ENSTRUP00000061911	ZnMc domain-containing protein.	Matrix metallopeptidase 16.	0.470
H2SI73_TAKRU	LOC101071448	ENSTRUP00000012101	ENSTRUP00000073204	ZnMc domain-containing protein.	Matrix metallopeptidase 15b.	0.521
H2SI73_TAKRU	LOC101075365	ENSTRUP00000012101	ENSTRUP00000020718	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.480
H2SI73_TAKRU	LOC101079398	ENSTRUP00000012101	ENSTRUP00000023509	ZnMc domain-containing protein.	Matrix metallopeptidase 11a.	0.485
H2SI73_TAKRU	LOC101080029	ENSTRUP00000012101	ENSTRUP00000072340	ZnMc domain-containing protein.	Matrix metallopeptidase 25b.	0.478
H2SI73_TAKRU	mmp14	ENSTRUP00000012101	ENSTRUP00000079174	ZnMc domain-containing protein.	Matrix metallopeptidase 14a (membrane-inserted).	0.411
H2SI73_TAKRU	mmp9	ENSTRUP00000012101	ENSTRUP00000001994	ZnMc domain-containing protein.	Uncharacterized protein.	0.483
LOC101061607	H2SI73_TAKRU	ENSTRUP00000062505	ENSTRUP00000012101	Matrix metallopeptidase 14b (membrane-inserted).	ZnMc domain-containing protein.	0.564
LOC101061607	mmp13	ENSTRUP00000062505	ENSTRUP00000070815	Matrix metallopeptidase 14b (membrane-inserted).	Matrix metalloproteinase.	0.573
LOC101061607	mmp14	ENSTRUP00000062505	ENSTRUP00000079174	Matrix metallopeptidase 14b (membrane-inserted).	Matrix metallopeptidase 14a (membrane-inserted).	0.901
LOC101061607	mmp2	ENSTRUP00000062505	ENSTRUP00000079652	Matrix metallopeptidase 14b (membrane-inserted).	Matrix metalloproteinase-2.	0.952
LOC101061607	mmp9	ENSTRUP00000062505	ENSTRUP00000001994	Matrix metallopeptidase 14b (membrane-inserted).	Uncharacterized protein.	0.447
LOC101061607	mmpf1	ENSTRUP00000062505	ENSTRUP00000008081	Matrix metallopeptidase 14b (membrane-inserted).	Matrix metalloproteinase.	0.577
LOC101063214	wap65-2	ENSTRUP00000040872	ENSTRUP00000080629	Vitronectin a.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.456
LOC101063812	wap65-2	ENSTRUP00000067819	ENSTRUP00000080629	Vitronectin b.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.456
LOC101069093	H2SI73_TAKRU	ENSTRUP00000073448	ENSTRUP00000012101	Matrix metallopeptidase 16b (membrane-inserted).	ZnMc domain-containing protein.	0.465
LOC101069093	mmp13	ENSTRUP00000073448	ENSTRUP00000070815	Matrix metallopeptidase 16b (membrane-inserted).	Matrix metalloproteinase.	0.479
LOC101069093	mmp2	ENSTRUP00000073448	ENSTRUP00000079652	Matrix metallopeptidase 16b (membrane-inserted).	Matrix metalloproteinase-2.	0.435