(50 nodes) High mobility group box domain network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101068543	Polybromo 1, like. (1631 aa)
	sox13	SRY-box transcription factor 13. (637 aa)
	tcf7l2	Transcription factor 7 like 2. (632 aa)
	tox2	TOX high mobility group box family member 2. (562 aa)
	lef1	Lymphoid enhancer-binding factor 1. (377 aa)
	pms1	PMS1 homolog 1, mismatch repair system component. (888 aa)
	SOX14	SRY-box transcription factor 14. (238 aa)
	LOC101071460	Uncharacterized protein. (483 aa)
	LOC101072929	Transcription factor SOX. (371 aa)
	LOC101065917	High mobility group box 2a. (214 aa)
	LOC101064892	SRY-box transcription factor 9b. (484 aa)
	LOC101062941	Upstream binding transcription factor, like. (697 aa)
	LOC101071427	SRY-box transcription factor 10. (499 aa)
	hmgxb4	HMG box domain containing 4a. (564 aa)
	sox17	SRY-box transcription factor 17. (399 aa)
	LOC101064548	SRY-box transcription factor 32. (333 aa)
	LOC101062288	TOX high mobility group box family member 4 a. (666 aa)
	SMARCE1	HMG box domain-containing protein. (431 aa)
	LOC101080222	Polybromo 1. (1557 aa)
	hmgxb3	HMG box domain containing 3. (1266 aa)
	tox4	TOX high mobility group box family member 4 b. (656 aa)
	LOC101072922	SRY-box transcription factor 19b. (300 aa)
	Sox2	SRY-box transcription factor 2. (331 aa)
	LOC101067170	High mobility group box 1b. (196 aa)
	ubtf	Upstream binding transcription factor. (735 aa)
	LOC101075571	HMG box domain-containing protein. (522 aa)
	hmg20b	High mobility group 20B. (291 aa)
	LOC101071517	SRY-box transcription factor 6. (797 aa)
	tcf7	Transcription factor 7. (491 aa)
	LOC101074632	HMG box domain-containing protein. (585 aa)
	LOC101066235	Transcription factor Sox1b. (333 aa)
	sox21	SRY-box transcription factor 21b. (248 aa)
	Sox12	Transcription factor SOX. (335 aa)
	cic	Capicua transcriptional repressor b. (2666 aa)
	LOC101064116	SRY-box transcription factor 3. (299 aa)
	LOC101070798	SRY-box transcription factor 9a. (489 aa)
	Sox8a	Transcription factor Sox8a. (462 aa)
	hmg20a	High mobility group 20A. (310 aa)
	wdhd1	WD_REPEATS_REGION domain-containing protein. (1122 aa)
	LOC101061934	HMG box domain-containing protein. (478 aa)
	LOC101063981	HMG box domain-containing protein. (237 aa)
	LOC105419230	Uncharacterized protein. (809 aa)
	sox7	SRY-box transcription factor 7. (410 aa)
	LOC101064967	SRY-box transcription factor 1a. (311 aa)
	LOC105416753	Uncharacterized protein. (461 aa)
	tcf7l1	Transcription factor 7 like 1b. (592 aa)
	tox3	TOX high mobility group box family member 3. (606 aa)
	ssrp1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (806 aa)
	LOC101066868	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (501 aa)
	LOC101064855	HMG box domain-containing protein. (742 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101061934	ssrp1	ENSTRUP00000035403	ENSTRUP00000086089	HMG box domain-containing protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.447
LOC101062288	ssrp1	ENSTRUP00000017080	ENSTRUP00000086089	TOX high mobility group box family member 4 a.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.447
LOC101062941	ssrp1	ENSTRUP00000023942	ENSTRUP00000086089	Upstream binding transcription factor, like.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.483
LOC101064116	LOC101064892	ENSTRUP00000054370	ENSTRUP00000024494	SRY-box transcription factor 3.	SRY-box transcription factor 9b.	0.419
LOC101064116	LOC101071427	ENSTRUP00000054370	ENSTRUP00000020908	SRY-box transcription factor 3.	SRY-box transcription factor 10.	0.406
LOC101064116	Sox8a	ENSTRUP00000054370	ENSTRUP00000054842	SRY-box transcription factor 3.	Transcription factor Sox8a.	0.417
LOC101064855	LOC101072929	ENSTRUP00000062417	ENSTRUP00000028436	HMG box domain-containing protein.	Transcription factor SOX.	0.449
LOC101064855	Sox12	ENSTRUP00000062417	ENSTRUP00000053530	HMG box domain-containing protein.	Transcription factor SOX.	0.449
LOC101064892	LOC101064116	ENSTRUP00000024494	ENSTRUP00000054370	SRY-box transcription factor 9b.	SRY-box transcription factor 3.	0.419
LOC101064892	LOC101071517	ENSTRUP00000024494	ENSTRUP00000079459	SRY-box transcription factor 9b.	SRY-box transcription factor 6.	0.482
LOC101064892	Sox2	ENSTRUP00000024494	ENSTRUP00000011608	SRY-box transcription factor 9b.	SRY-box transcription factor 2.	0.411
LOC101064967	Sox8a	ENSTRUP00000056326	ENSTRUP00000054842	SRY-box transcription factor 1a.	Transcription factor Sox8a.	0.406
LOC101065917	LOC101067170	ENSTRUP00000024718	ENSTRUP00000011525	High mobility group box 2a.	High mobility group box 1b.	0.405
LOC101065917	ssrp1	ENSTRUP00000024718	ENSTRUP00000086089	High mobility group box 2a.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.447
LOC101066235	LOC101071517	ENSTRUP00000048387	ENSTRUP00000079459	Transcription factor Sox1b.	SRY-box transcription factor 6.	0.409
LOC101066235	Sox8a	ENSTRUP00000048387	ENSTRUP00000054842	Transcription factor Sox1b.	Transcription factor Sox8a.	0.453
LOC101066868	LOC101068543	ENSTRUP00000061238	ENSTRUP00000012798	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	Polybromo 1, like.	0.810
LOC101066868	LOC101080222	ENSTRUP00000061238	ENSTRUP00000014725	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	Polybromo 1.	0.810
LOC101067170	LOC101065917	ENSTRUP00000011525	ENSTRUP00000024718	High mobility group box 1b.	High mobility group box 2a.	0.405
LOC101067170	ssrp1	ENSTRUP00000011525	ENSTRUP00000086089	High mobility group box 1b.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.447