STRINGSTRING
ybx1 ybx1 RPA1 RPA1 mcm6 mcm6 psmc1 psmc1 eif1ax eif1ax mcm4 mcm4 rngtt rngtt nabp1 nabp1 rpa1 rpa1 shld2 shld2 LOC101073324 LOC101073324 dhx8 dhx8 brca2 brca2 dis3l2 dis3l2 psmc4 psmc4 SRBD1 SRBD1 dars2 dars2 mcm2 mcm2 psmc3 psmc3 polr2h polr2h mcm8 mcm8 H2TER7_TAKRU H2TER7_TAKRU Helz2 Helz2 LOC101078394 LOC101078394 stn1 stn1 lig4 lig4 dis3 dis3 lig3 lig3 EIF5AL1 EIF5AL1 YBX2 YBX2 rmi2 rmi2 zcchc17 zcchc17 ccar1 ccar1 nars2 nars2 yars1 yars1 pot1 pot1 meiob meiob kars1 kars1 eif2s1 eif2s1 mrps17 mrps17 polr2g polr2g LOC105416353 LOC105416353 spout1 spout1 carhsp1 carhsp1 supt6h supt6h LOC101078201 LOC101078201 mcm5 mcm5 ten1 ten1 rpa3 rpa3 rpl8 rpl8 LOC101066313 LOC101066313 mcm3 mcm3 psmc6 psmc6 aimp1 aimp1 rps11 rps11 LOC101063405 LOC101063405 ttc14 ttc14 dars1 dars1 rpa2 rpa2 csdc2 csdc2 exosc2 exosc2 CSDE1 CSDE1 radx radx LOC101062380 LOC101062380 H2TGF9_TAKRU H2TGF9_TAKRU mcm7 mcm7 st6galnac6 st6galnac6 MRPS12 MRPS12 PNPT1 PNPT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ybx1Y box binding protein 1. (325 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (713 aa)
mcm6DNA helicase; Belongs to the MCM family. (826 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (443 aa)
eif1axEukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (169 aa)
mcm4DNA helicase; Belongs to the MCM family. (869 aa)
rngttPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (599 aa)
nabp1Nucleic acid binding protein 1a. (219 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
shld2Si:ch211-134m17.9. (859 aa)
LOC101073324Polymerase (RNA) III (DNA directed) polypeptide H. (215 aa)
dhx8DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1185 aa)
brca2BRCA2 DNA repair associated. (2718 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1042 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
SRBD1S1 RNA binding domain 1. (1017 aa)
dars2Aspartyl-tRNA synthetase 2, mitochondrial. (640 aa)
mcm2DNA helicase; Belongs to the MCM family. (896 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (874 aa)
H2TER7_TAKRURibosomal protein S28. (53 aa)
Helz2RNB domain-containing protein. (2491 aa)
LOC101078394RPA_C domain-containing protein. (224 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (363 aa)
lig4DNA ligase. (908 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (953 aa)
lig3DNA ligase. (998 aa)
EIF5AL1Eukaryotic translation initiation factor 5A. (155 aa)
YBX2Y-box binding protein 2. (373 aa)
rmi2RecQ mediated genome instability 2. (138 aa)
zcchc17Zinc finger, CCHC domain containing 17. (243 aa)
ccar1Cell division cycle and apoptosis regulator 1. (1236 aa)
nars2Asparaginyl-tRNA synthetase 2, mitochondrial. (474 aa)
yars1Tyrosine--tRNA ligase. (528 aa)
pot1Protection of telomeres 1 homolog. (814 aa)
meiobMethionine sulfoxide reductase B1b. (483 aa)
kars1Lysine--tRNA ligase. (595 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
mrps17Mitochondrial ribosomal protein S17. (148 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
LOC105416353Uncharacterized protein. (2102 aa)
spout1SPOUT domain containing methyltransferase 1. (381 aa)
carhsp1Calcium regulated heat stable protein 1. (159 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1744 aa)
LOC101078201Uncharacterized protein. (887 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
ten1TEN1 subunit of CST complex. (121 aa)
rpa3Replication protein A3. (122 aa)
rpl8Ribosomal protein L8. (276 aa)
LOC101066313Exosome component 3. (250 aa)
mcm3DNA helicase; Belongs to the MCM family. (813 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (411 aa)
aimp1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (324 aa)
rps11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (187 aa)
LOC101063405Uncharacterized protein. (1135 aa)
ttc14Tetratricopeptide repeat domain 14. (743 aa)
dars1Aspartyl-tRNA synthetase. (530 aa)
rpa2Replication protein A2. (280 aa)
csdc2Cold shock domain containing C2, RNA binding a. (158 aa)
exosc2Exosome component 2. (296 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (905 aa)
radxRPA1 related single stranded DNA binding protein. (819 aa)
LOC101062380Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (425 aa)
H2TGF9_TAKRULin-28 homolog A (C. elegans). (205 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (732 aa)
st6galnac6Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (307 aa)
MRPS12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (143 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (797 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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