94 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101071220	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1301 aa)
	tnk1	Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (744 aa)
	LOC101062908	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
	LOC101073085	Eph receptor A2 a. (974 aa)
	mertk	C-mer proto-oncogene tyrosine kinase a. (939 aa)
	LOC101074430	Tyrosine-protein kinase receptor. (1394 aa)
	ntrk1	Tyrosine-protein kinase receptor. (624 aa)
	LOC101067733	EPH receptor B1. (1013 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1374 aa)
	LOC101079603	Tyrosine-protein kinase receptor. (1416 aa)
	AXL	AXL receptor tyrosine kinase. (933 aa)
	fgfr1	Fibroblast growth factor receptor. (845 aa)
	LOC101068778	Tyrosine-protein kinase. (1125 aa)
	csk	Tyrosine-protein kinase. (511 aa)
	LOC101067972	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (957 aa)
	LOC101073748	Receptor protein-tyrosine kinase. (1189 aa)
	fgfr2	Fibroblast growth factor receptor. (838 aa)
	src	Tyrosine-protein kinase. (552 aa)
	tie1	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1132 aa)
	LOC101073964	Fibroblast growth factor receptor. (729 aa)
	flt3	Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (984 aa)
	LOC101064553	Tyrosine-protein kinase. (588 aa)
	ephb4	Eph receptor B4a. (985 aa)
	LOC101078652	KIT proto-oncogene, receptor tyrosine kinase b. (963 aa)
	LOC101068538	Fibroblast growth factor receptor 4. (1053 aa)
	alk	Tyrosine-protein kinase receptor. (1740 aa)
	jak1	Tyrosine-protein kinase. (1170 aa)
	LOC101080137	Eph LBD domain-containing protein. (988 aa)
	epha3	Eph receptor A3. (994 aa)
	LOC101069639	Tyrosine-protein kinase. (537 aa)
	ntrk3	Neurotrophic tyrosine kinase, receptor, type 3b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (848 aa)
	ddr1	Discoidin domain receptor tyrosine kinase 1. (879 aa)
	tyk2	Tyrosine-protein kinase. (1144 aa)
	abl1	Tyrosine-protein kinase. (1115 aa)
	itk	Tyrosine-protein kinase. (622 aa)
	LOC101067410	Eph receptor B3a. (926 aa)
	btk	Tyrosine-protein kinase. (634 aa)
	kit	Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. (991 aa)
	H2RIU2_TAKRU	Uncharacterized protein. (278 aa)
	LOC101063427	Tyrosine-protein kinase receptor. (1426 aa)
	EPHA6	EPH receptor A6. (1012 aa)
	egfr	Receptor protein-tyrosine kinase. (1189 aa)
	ltk	Tyrosine-protein kinase receptor. (1520 aa)
	LOC101064431	Discoidin domain receptor family, member 2, like. (889 aa)
	YES1	Tyrosine-protein kinase. (549 aa)
	ddr2	Discoidin domain receptor tyrosine kinase 2a. (869 aa)
	hck	Tyrosine-protein kinase. (540 aa)
	H2TI00_TAKRU	Tyrosine-protein kinase receptor. (838 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (897 aa)
	LOC101079402	Tyrosine-protein kinase receptor. (879 aa)
	LOC101074083	Tyrosine-protein kinase receptor. (1393 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1161 aa)
	LOC101074687	Receptor protein-tyrosine kinase. (1372 aa)
	kdr	Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1365 aa)
	LOC101072875	Tyrosine-protein kinase. (544 aa)
	LOC101071929	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1053 aa)
	matk	Tyrosine-protein kinase. (511 aa)
	met	Uncharacterized protein. (1425 aa)
	LOC101071166	Uncharacterized protein. (1088 aa)
	LOC101070937	Eph receptor A4b. (983 aa)
	LOC101078156	Uncharacterized protein. (928 aa)
	LOC101065603	Eph receptor B2b. (1000 aa)
	LOC101063860	Fibroblast growth factor receptor 3. (842 aa)
	csf1r	Macrophage colony-stimulating factor 1 receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...] (980 aa)
	epha4	Eph receptor A4, like. (991 aa)
	LOC101065281	Tyrosine-protein kinase. (552 aa)
	erbb4	Receptor protein-tyrosine kinase. (1406 aa)
	zap70	Tyrosine-protein kinase. (631 aa)
	pdgfra	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...] (1499 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)
	LOC101068187	Eph LBD domain-containing protein. (1026 aa)
	LOC101078202	Tyrosine-protein kinase receptor. (581 aa)
	LOC101069728	Eph receptor A2 b. (987 aa)
	tnk2	Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1110 aa)
	LOC101080143	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...] (1023 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (925 aa)
	fyn	Tyrosine-protein kinase. (538 aa)
	LOC101074842	Receptor protein-tyrosine kinase. (1300 aa)
	lck	Tyrosine-protein kinase. (511 aa)
	LOC101061130	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1025 aa)
	flt4	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1394 aa)
	LOC101069940	Eph receptor B2a. (1009 aa)
	abl2	Tyrosine-protein kinase. (1214 aa)
	frk	Tyrosine-protein kinase. (515 aa)
	blk	Tyrosine-protein kinase. (479 aa)
	ephb3	Uncharacterized protein. (1013 aa)
	pdgfrb	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...] (1129 aa)
	LOC101077037	Tyrosine kinase, non-receptor, 2a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1077 aa)
	LOC101063506	Receptor protein-tyrosine kinase. (1004 aa)
	ptk2b	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa)
	LOC101072239	Apoptosis-associated tyrosine kinase a. (1602 aa)
	fer	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (825 aa)
	syk	Tyrosine-protein kinase. (619 aa)
	LOC101071528	Macrophage stimulating 1 receptor a. (1375 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101061130	LOC101065281	ENSTRUP00000011257	ENSTRUP00000084615	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Tyrosine-protein kinase.	0.912
LOC101061130	src	ENSTRUP00000011257	ENSTRUP00000047001	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Tyrosine-protein kinase.	0.912
LOC101062908	LOC101064553	ENSTRUP00000028189	ENSTRUP00000053431	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.501
LOC101062908	LOC101065281	ENSTRUP00000028189	ENSTRUP00000084615	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.651
LOC101062908	LOC101068778	ENSTRUP00000028189	ENSTRUP00000043195	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.524
LOC101062908	LOC101069639	ENSTRUP00000028189	ENSTRUP00000059214	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.592
LOC101062908	LOC101071220	ENSTRUP00000028189	ENSTRUP00000026445	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.425
LOC101062908	LOC101071528	ENSTRUP00000028189	ENSTRUP00000025241	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Macrophage stimulating 1 receptor a.	0.520
LOC101062908	LOC101072875	ENSTRUP00000028189	ENSTRUP00000076501	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.592
LOC101062908	LOC101073748	ENSTRUP00000028189	ENSTRUP00000044719	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.498
LOC101062908	LOC101074687	ENSTRUP00000028189	ENSTRUP00000074942	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.456
LOC101062908	LOC101074842	ENSTRUP00000028189	ENSTRUP00000010278	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.456
LOC101062908	YES1	ENSTRUP00000028189	ENSTRUP00000069567	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.592
LOC101062908	blk	ENSTRUP00000028189	ENSTRUP00000015829	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.592
LOC101062908	csk	ENSTRUP00000028189	ENSTRUP00000043742	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.554
LOC101062908	egfr	ENSTRUP00000028189	ENSTRUP00000067832	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.498
LOC101062908	erbb4	ENSTRUP00000028189	ENSTRUP00000087920	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.456
LOC101062908	flt4	ENSTRUP00000028189	ENSTRUP00000013679	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.425
LOC101062908	frk	ENSTRUP00000028189	ENSTRUP00000015523	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.501
LOC101062908	fyn	ENSTRUP00000028189	ENSTRUP00000008304	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.501