24 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	gab1	GRB2-associated binding protein 1. (749 aa)
	RNF222	Ring finger protein 222. (239 aa)
	LOC101067191	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (491 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSTRUP00000053164	EGF-like domain-containing protein. (114 aa)
	LOC101061204	Uncharacterized protein. (205 aa)
	pxn	Uncharacterized protein. (1106 aa)
	LOC101076984	Transforming growth factor, alpha. (276 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1253 aa)
	LOC101078686	EGF-like domain-containing protein. (194 aa)
	CSK	C-terminal Src kinase. (455 aa)
	CSK-2	Tyrosine-protein kinase CSK isoform X1. (461 aa)
	ENSTRUP00000074040	annotation not available (139 aa)
	LOC101061071	Leupaxin. (398 aa)
	ENSTRUP00000078829	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
	LOC101065281	Tyrosine-protein kinase. (552 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1224 aa)
	src	Tyrosine-protein kinase. (552 aa)
	LOC101078435	PH domain-containing protein. (744 aa)
	csk	Tyrosine-protein kinase. (511 aa)
	LOC101076422	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (231 aa)
	PXN	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (522 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	ENSTRUP00000053164	ENSTRUP00000060471	ENSTRUP00000053164	C-terminal Src kinase.	EGF-like domain-containing protein.	0.406
CSK	LOC101061071	ENSTRUP00000060471	ENSTRUP00000074730	C-terminal Src kinase.	Leupaxin.	0.624
CSK	LOC101061204	ENSTRUP00000060471	ENSTRUP00000049272	C-terminal Src kinase.	Uncharacterized protein.	0.529
CSK	LOC101065281	ENSTRUP00000060471	ENSTRUP00000084615	C-terminal Src kinase.	Tyrosine-protein kinase.	0.652
CSK	LOC101076984	ENSTRUP00000060471	ENSTRUP00000056700	C-terminal Src kinase.	Transforming growth factor, alpha.	0.444
CSK	LOC101078435	ENSTRUP00000060471	ENSTRUP00000044729	C-terminal Src kinase.	PH domain-containing protein.	0.454
CSK	PXN	ENSTRUP00000060471	ENSTRUP00000040413	C-terminal Src kinase.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.595
CSK	TGFB1I1	ENSTRUP00000060471	ENSTRUP00000013270	C-terminal Src kinase.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.595
CSK	gab1	ENSTRUP00000060471	ENSTRUP00000035712	C-terminal Src kinase.	GRB2-associated binding protein 1.	0.454
CSK	grb2	ENSTRUP00000060471	ENSTRUP00000020659	C-terminal Src kinase.	Growth factor receptor-bound protein 2b.	0.529
CSK	pxn	ENSTRUP00000060471	ENSTRUP00000055490	C-terminal Src kinase.	Uncharacterized protein.	0.595
CSK	src	ENSTRUP00000060471	ENSTRUP00000047001	C-terminal Src kinase.	Tyrosine-protein kinase.	0.651
CSK-2	ENSTRUP00000053164	ENSTRUP00000071992	ENSTRUP00000053164	Tyrosine-protein kinase CSK isoform X1.	EGF-like domain-containing protein.	0.406
CSK-2	LOC101061071	ENSTRUP00000071992	ENSTRUP00000074730	Tyrosine-protein kinase CSK isoform X1.	Leupaxin.	0.624
CSK-2	LOC101061204	ENSTRUP00000071992	ENSTRUP00000049272	Tyrosine-protein kinase CSK isoform X1.	Uncharacterized protein.	0.529
CSK-2	LOC101065281	ENSTRUP00000071992	ENSTRUP00000084615	Tyrosine-protein kinase CSK isoform X1.	Tyrosine-protein kinase.	0.650
CSK-2	LOC101076984	ENSTRUP00000071992	ENSTRUP00000056700	Tyrosine-protein kinase CSK isoform X1.	Transforming growth factor, alpha.	0.444
CSK-2	LOC101078435	ENSTRUP00000071992	ENSTRUP00000044729	Tyrosine-protein kinase CSK isoform X1.	PH domain-containing protein.	0.454
CSK-2	PXN	ENSTRUP00000071992	ENSTRUP00000040413	Tyrosine-protein kinase CSK isoform X1.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.595
CSK-2	TGFB1I1	ENSTRUP00000071992	ENSTRUP00000013270	Tyrosine-protein kinase CSK isoform X1.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.595