31 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stat1	Signal transducer and activator of transcription. (763 aa)
	LOC101075732	Uncharacterized protein LOC101075732 isoform X1. (505 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1056 aa)
	LOC101063539	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (200 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101067191	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101069736	Zgc:55558. (187 aa)
	pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
	LOC101067369	Growth factor receptor bound protein 7. (497 aa)
	pdgfrb	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...] (1129 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	nedd9	Neural precursor cell expressed, developmentally down-regulated 9. (803 aa)
	LOC101065989	CRK proto-oncogene, adaptor protein. (319 aa)
	nck2	Cytoplasmic protein. (396 aa)
	LOC101071345	Signal transducer and activator of transcription. (785 aa)
	LOC101065277	Signal transducer and activator of transcription. (794 aa)
	nck1	Cytoplasmic protein. (399 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1194 aa)
	src	Tyrosine-protein kinase. (552 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (542 aa)
	LOC101061204	Uncharacterized protein. (205 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1253 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
	LOC115253205	PiggyBac transposable element-derived protein 4-like. (411 aa)
	ENSTRUP00000078829	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (905 aa)
	LOC101065281	Tyrosine-protein kinase. (552 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1224 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSTRUP00000078829	ENSTRUP00000080673	ENSTRUP00000078829	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.509
CSDE1	LOC101061204	ENSTRUP00000080673	ENSTRUP00000049272	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.593
CSDE1	LOC101067191	ENSTRUP00000080673	ENSTRUP00000016050	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.509
CSDE1	PIK3CA	ENSTRUP00000080673	ENSTRUP00000009530	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.509
CSDE1	grb2	ENSTRUP00000080673	ENSTRUP00000020659	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.593
CSDE1	pdgfrb	ENSTRUP00000080673	ENSTRUP00000018654	Cold shock domain containing E1, RNA-binding.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]	0.509
CSDE1	pik3cb	ENSTRUP00000080673	ENSTRUP00000017655	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.509
CSDE1	rapgef1	ENSTRUP00000080673	ENSTRUP00000046911	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.469
CSDE1	rasa1	ENSTRUP00000080673	ENSTRUP00000003275	Cold shock domain containing E1, RNA-binding.	RAS p21 protein activator (GTPase activating protein) 1a.	0.794
ENSTRUP00000078829	CSDE1	ENSTRUP00000078829	ENSTRUP00000080673	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cold shock domain containing E1, RNA-binding.	0.509
ENSTRUP00000078829	LOC101061204	ENSTRUP00000078829	ENSTRUP00000049272	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.540
ENSTRUP00000078829	LOC101063539	ENSTRUP00000078829	ENSTRUP00000006263	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.412
ENSTRUP00000078829	LOC101067369	ENSTRUP00000078829	ENSTRUP00000017696	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Growth factor receptor bound protein 7.	0.415
ENSTRUP00000078829	LOC101069736	ENSTRUP00000078829	ENSTRUP00000016293	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zgc:55558.	0.543
ENSTRUP00000078829	LOC115253205	ENSTRUP00000078829	ENSTRUP00000062504	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PiggyBac transposable element-derived protein 4-like.	0.502
ENSTRUP00000078829	grb2	ENSTRUP00000078829	ENSTRUP00000020659	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Growth factor receptor-bound protein 2b.	0.540
ENSTRUP00000078829	hras	ENSTRUP00000078829	ENSTRUP00000052118	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	HRas proto-oncogene, GTPase a.	0.542
ENSTRUP00000078829	kras	ENSTRUP00000078829	ENSTRUP00000052814	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.543
ENSTRUP00000078829	pdgfrb	ENSTRUP00000078829	ENSTRUP00000018654	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]	0.522
LOC101061204	CSDE1	ENSTRUP00000049272	ENSTRUP00000080673	Uncharacterized protein.	Cold shock domain containing E1, RNA-binding.	0.593