22 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ptn	Pleiotrophin. (165 aa)
	prdm1	Uncharacterized protein. (837 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	H2SMC4_TAKRU	PR domain containing 1b, with ZNF domain. (730 aa)
	HDAC3	Histone deacetylase 3. (476 aa)
	LOC101067191	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
	LOC101074732	Uncharacterized protein. (749 aa)
	LOC101073316	Tyrosine-protein kinase. (1110 aa)
	LOC101071688	Protein tyrosine phosphatase receptor type Z1b. (1254 aa)
	LOC101070643	E1A binding protein p300 a. (2046 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (594 aa)
	alk	Tyrosine-protein kinase receptor. (1740 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
	ENSTRUP00000064066	E1A binding protein p300 b. (2625 aa)
	ltk	Tyrosine-protein kinase receptor. (1520 aa)
	LOC115248448	E1A binding protein p300 b. (2795 aa)
	LOC101071379	MYCN proto-oncogene, bHLH transcription factor. (467 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (652 aa)
	ENSTRUP00000078829	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
	mdk	Midkine b. (232 aa)
	shc4	SHC-transforming protein 4 isoform X2. (470 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000064066	HDAC3	ENSTRUP00000064066	ENSTRUP00000015206	E1A binding protein p300 b.	Histone deacetylase 3.	0.662
ENSTRUP00000078829	alk	ENSTRUP00000078829	ENSTRUP00000057849	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase receptor.	0.470
ENSTRUP00000078829	ltk	ENSTRUP00000078829	ENSTRUP00000068449	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase receptor.	0.470
ENSTRUP00000078829	mdk	ENSTRUP00000078829	ENSTRUP00000081574	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Midkine b.	0.451
ENSTRUP00000078829	ptpn6	ENSTRUP00000078829	ENSTRUP00000069984	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein tyrosine phosphatase non-receptor type 6.	0.456
HDAC3	ENSTRUP00000064066	ENSTRUP00000015206	ENSTRUP00000064066	Histone deacetylase 3.	E1A binding protein p300 b.	0.662
HDAC3	LOC101070643	ENSTRUP00000015206	ENSTRUP00000043685	Histone deacetylase 3.	E1A binding protein p300 a.	0.662
HDAC3	LOC115248448	ENSTRUP00000015206	ENSTRUP00000069118	Histone deacetylase 3.	E1A binding protein p300 b.	0.662
LOC101067191	PIK3CA	ENSTRUP00000016050	ENSTRUP00000009530	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.900
LOC101067191	alk	ENSTRUP00000016050	ENSTRUP00000057849	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Tyrosine-protein kinase receptor.	0.470
LOC101067191	ltk	ENSTRUP00000016050	ENSTRUP00000068449	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Tyrosine-protein kinase receptor.	0.470
LOC101067191	mdk	ENSTRUP00000016050	ENSTRUP00000081574	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Midkine b.	0.451
LOC101067191	pik3cb	ENSTRUP00000016050	ENSTRUP00000017655	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.904
LOC101067191	plcg1	ENSTRUP00000016050	ENSTRUP00000058192	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.747
LOC101067191	ptpn6	ENSTRUP00000016050	ENSTRUP00000069984	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Protein tyrosine phosphatase non-receptor type 6.	0.456
LOC101070643	HDAC3	ENSTRUP00000043685	ENSTRUP00000015206	E1A binding protein p300 a.	Histone deacetylase 3.	0.662
LOC101071379	alk	ENSTRUP00000069294	ENSTRUP00000057849	MYCN proto-oncogene, bHLH transcription factor.	Tyrosine-protein kinase receptor.	0.555
LOC101071379	ltk	ENSTRUP00000069294	ENSTRUP00000068449	MYCN proto-oncogene, bHLH transcription factor.	Tyrosine-protein kinase receptor.	0.555
LOC101071688	alk	ENSTRUP00000030441	ENSTRUP00000057849	Protein tyrosine phosphatase receptor type Z1b.	Tyrosine-protein kinase receptor.	0.562
LOC101071688	ltk	ENSTRUP00000030441	ENSTRUP00000068449	Protein tyrosine phosphatase receptor type Z1b.	Tyrosine-protein kinase receptor.	0.562