STRINGSTRING
fgf22 fgf22 LOC101067016 LOC101067016 ENSTRUP00000084403 ENSTRUP00000084403 shc4 shc4 frs2 frs2 LOC101075629 LOC101075629 ENSTRUP00000088182 ENSTRUP00000088182 LOC101077596 LOC101077596 atp6v1e1 atp6v1e1 LOC101064999 LOC101064999 PIK3CA PIK3CA LOC101071950 LOC101071950 LOC101079556 LOC101079556 LOC101063545 LOC101063545 LOC101069496 LOC101069496 LOC101067191 LOC101067191 atp6v1f atp6v1f fgf5 fgf5 atp6v1a atp6v1a LOC101067940 LOC101067940 ENSTRUP00000004692 ENSTRUP00000004692 H2SIS4_TAKRU H2SIS4_TAKRU LOC101064761 LOC101064761 pik3cb pik3cb grb2 grb2 LOC101076816 LOC101076816 AKT2 AKT2 LOC101076056 LOC101076056 LOC101071264 LOC101071264 ENSTRUP00000023848 ENSTRUP00000023848 LOC101076043 LOC101076043 klb klb FGF6 FGF6 LOC101065438 LOC101065438 LOC101068171 LOC101068171 LOC101061209 LOC101061209 FGF6-2 FGF6-2 atp6v1h atp6v1h atp6ap1 atp6ap1 LOC101074430 LOC101074430 gab2 gab2 ptpn1 ptpn1 ENSTRUP00000052849 ENSTRUP00000052849 LOC101075539 LOC101075539 LOC101065833 LOC101065833 fgf16 fgf16 atp6v1d atp6v1d LOC101068011 LOC101068011 LOC101069856 LOC101069856 ide ide LOC115253299 LOC115253299 shc1 shc1 LOC101068538 LOC101068538 fgf7 fgf7 fgf8 fgf8 LOC101078100 LOC101078100 LOC101077596-2 LOC101077596-2 LOC101064814 LOC101064814 ENSTRUP00000065063 ENSTRUP00000065063 LOC101065226 LOC101065226 LOC101071373 LOC101071373 FGF13 FGF13 LOC105418820 LOC105418820 LOC101075382 LOC101075382 LOC101062972 LOC101062972 ENSTRUP00000073441 ENSTRUP00000073441 H2VAJ3_TAKRU H2VAJ3_TAKRU fgf3 fgf3 LOC101074083 LOC101074083 pde3b pde3b LOC101063084 LOC101063084 atp6v0a2 atp6v0a2 atp6v0b atp6v0b gab1 gab1 LOC101073070 LOC101073070 atp6v0a1 atp6v0a1 LOC101070231 LOC101070231 pdpk1 pdpk1 LOC101064303 LOC101064303 fgfr1 fgfr1 fgf10 fgf10 LOC101072050 LOC101072050 LOC101078435 LOC101078435 fgf17 fgf17 fgfr2 fgfr2 LOC101073964 LOC101073964 ATP6V1B2 ATP6V1B2 LOC101072524 LOC101072524 LOC101067042 LOC101067042 LOC101061204 LOC101061204 cnst cnst LOC101075728 LOC101075728 LOC101069995 LOC101069995 ENSTRUP00000078829 ENSTRUP00000078829 LOC101061664 LOC101061664 atp6v1g1 atp6v1g1 LCT LCT LOC101063860 LOC101063860 H2S3Y8_TAKRU H2S3Y8_TAKRU LOC101070196 LOC101070196
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
LOC101067016Growth factor receptor-bound protein 10b. (630 aa)
ENSTRUP00000084403Fibroblast growth factor 23-like. (141 aa)
shc4SHC-transforming protein 4 isoform X2. (470 aa)
frs2Fibroblast growth factor receptor substrate 2b. (1049 aa)
LOC101075629Protein tyrosine phosphatase receptor type Fb. (1911 aa)
ENSTRUP00000088182annotation not available (138 aa)
LOC101077596Klotho; Belongs to the glycosyl hydrolase 1 family. (976 aa)
atp6v1e1ATPase H+ transporting V1 subunit E1a. (226 aa)
LOC101064999Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101071950V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
LOC101079556Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (179 aa)
LOC101063545Lens intrinsic membrane protein 2.1. (173 aa)
LOC101069496Insulin receptor substrate 2b. (1096 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
LOC101067940Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
ENSTRUP00000004692LOW QUALITY PROTEIN: lactase-phlorizin hydrolase-like. (606 aa)
H2SIS4_TAKRUUncharacterized protein. (229 aa)
LOC101064761Thioesterase superfamily member 4. (253 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
grb2Growth factor receptor-bound protein 2b. (220 aa)
LOC101076816V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (407 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101076056V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (826 aa)
LOC101071264ATPase H+ transporting accessory protein 1b. (467 aa)
ENSTRUP00000023848Lactase-like protein isoform X2. (291 aa)
LOC101076043Insulin receptor substrate 2a. (1054 aa)
klbKlotho beta. (1046 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101065438Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC101068171V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
LOC101061209Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (474 aa)
LOC101074430Tyrosine-protein kinase receptor. (1394 aa)
gab2GRB2-associated binding protein 2. (679 aa)
ptpn1Tyrosine-protein phosphatase non-receptor type. (440 aa)
ENSTRUP00000052849Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (148 aa)
LOC101075539Consortin, connexin sorting protein b. (371 aa)
LOC101065833Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
LOC101068011Lens intrinsic membrane protein 2.3. (173 aa)
LOC101069856Tribbles pseudokinase 3. (349 aa)
ideInsulin-degrading enzyme; Belongs to the peptidase M16 family. (1056 aa)
LOC115253299V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (594 aa)
LOC101068538Fibroblast growth factor receptor 4. (1053 aa)
fgf7Fibroblast growth factor 7; Belongs to the heparin-binding growth factors family. (238 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC101078100Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (302 aa)
LOC101077596-2Klotho-like. (976 aa)
LOC101064814V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (871 aa)
ENSTRUP00000065063ATPase H+ transporting V1 subunit C2. (338 aa)
LOC101065226Insulin-like. (172 aa)
LOC101071373Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (284 aa)
LOC105418820Insulin. (114 aa)
LOC101075382Growth factor receptor-bound protein 10a. (606 aa)
LOC101062972V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
ENSTRUP00000073441ATPase H+ transporting accessory protein 1a. (460 aa)
H2VAJ3_TAKRUPeptidase_M16_C domain-containing protein. (1087 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
LOC101074083Tyrosine-protein kinase receptor. (1393 aa)
pde3bPhosphodiesterase. (1108 aa)
LOC101063084Protein tyrosine phosphatase receptor type Fa. (1906 aa)
atp6v0a2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (852 aa)
atp6v0bATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
gab1GRB2-associated binding protein 1. (749 aa)
LOC101073070Lactase-like b; Belongs to the glycosyl hydrolase 1 family. (539 aa)
atp6v0a1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (850 aa)
LOC101070231Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (559 aa)
LOC101064303Nardilysin a (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (971 aa)
fgfr1Fibroblast growth factor receptor. (845 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
LOC101072050Uncharacterized protein. (618 aa)
LOC101078435PH domain-containing protein. (744 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa)
fgfr2Fibroblast growth factor receptor. (838 aa)
LOC101073964Fibroblast growth factor receptor. (729 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (537 aa)
LOC101072524V-type proton ATPase subunit B, brain isoform. (504 aa)
LOC101067042Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
LOC101061204Uncharacterized protein. (205 aa)
cnstConsortin_C domain-containing protein. (788 aa)
LOC101075728ATPase H+ transporting accessory protein 1 like b. (341 aa)
LOC101069995Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
ENSTRUP00000078829Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
LOC101061664ATPase H+ transporting V1 subunit E1b. (246 aa)
atp6v1g1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (114 aa)
LCTUncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (1924 aa)
LOC101063860Fibroblast growth factor receptor 3. (842 aa)
H2S3Y8_TAKRUFibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC101070196Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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