9 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSTRUP00000078829	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101067191	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	LOC101064315	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (756 aa)
	gab1	GRB2-associated binding protein 1. (749 aa)
	LOC101078435	PH domain-containing protein. (744 aa)
	LOC101061204	Uncharacterized protein. (205 aa)
	met	Uncharacterized protein. (1425 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000078829	LOC101061204	ENSTRUP00000078829	ENSTRUP00000049272	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.540
ENSTRUP00000078829	LOC101078435	ENSTRUP00000078829	ENSTRUP00000044729	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PH domain-containing protein.	0.447
ENSTRUP00000078829	gab1	ENSTRUP00000078829	ENSTRUP00000035712	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	GRB2-associated binding protein 1.	0.447
ENSTRUP00000078829	grb2	ENSTRUP00000078829	ENSTRUP00000020659	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Growth factor receptor-bound protein 2b.	0.540
ENSTRUP00000078829	met	ENSTRUP00000078829	ENSTRUP00000078415	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.625
LOC101061204	ENSTRUP00000078829	ENSTRUP00000049272	ENSTRUP00000078829	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
LOC101061204	LOC101064315	ENSTRUP00000049272	ENSTRUP00000034166	Uncharacterized protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.461
LOC101061204	LOC101067191	ENSTRUP00000049272	ENSTRUP00000016050	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.540
LOC101061204	LOC101078435	ENSTRUP00000049272	ENSTRUP00000044729	Uncharacterized protein.	PH domain-containing protein.	0.990
LOC101061204	PIK3CA	ENSTRUP00000049272	ENSTRUP00000009530	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.540
LOC101061204	gab1	ENSTRUP00000049272	ENSTRUP00000035712	Uncharacterized protein.	GRB2-associated binding protein 1.	0.990
LOC101061204	grb2	ENSTRUP00000049272	ENSTRUP00000020659	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.903
LOC101061204	met	ENSTRUP00000049272	ENSTRUP00000078415	Uncharacterized protein.	Uncharacterized protein.	0.938
LOC101064315	LOC101061204	ENSTRUP00000034166	ENSTRUP00000049272	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.461
LOC101064315	LOC101078435	ENSTRUP00000034166	ENSTRUP00000044729	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	PH domain-containing protein.	0.550
LOC101064315	gab1	ENSTRUP00000034166	ENSTRUP00000035712	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GRB2-associated binding protein 1.	0.550
LOC101064315	grb2	ENSTRUP00000034166	ENSTRUP00000020659	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Growth factor receptor-bound protein 2b.	0.461
LOC101064315	met	ENSTRUP00000034166	ENSTRUP00000078415	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.962
LOC101067191	LOC101061204	ENSTRUP00000016050	ENSTRUP00000049272	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.540
LOC101067191	LOC101078435	ENSTRUP00000016050	ENSTRUP00000044729	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	PH domain-containing protein.	0.942