STRINGSTRING
ENSTRUP00000081534 ENSTRUP00000081534 ENSTRUP00000001508 ENSTRUP00000001508 GRB14 GRB14 LOC101066865 LOC101066865 LOC101075115 LOC101075115 PIK3CA PIK3CA dok6 dok6 pdlim5 pdlim5 LOC101069496 LOC101069496 LOC101067191 LOC101067191 shank1 shank1 PSPN PSPN pik3cb pik3cb ENSTRUP00000078829 ENSTRUP00000078829 LOC101067369 LOC101067369 grb2 grb2 LOC101076043 LOC101076043 SHC3 SHC3 LOC101063692 LOC101063692 LOC101067085 LOC101067085 LOC101061527 LOC101061527 gab2 gab2 gdnf gdnf LOC101074872 LOC101074872 gab1 gab1 LOC101073659 LOC101073659 LOC101079530 LOC101079530 LOC101078435 LOC101078435 src src LOC101075301 LOC101075301 LOC101061204 LOC101061204 dok1 dok1 LOC101067016 LOC101067016 mapk7 mapk7 pik3cd pik3cd LOC101064722 LOC101064722 shc1 shc1 fndc3a fndc3a plcg1 plcg1 LOC101065244 LOC101065244 shank3 shank3 ENSTRUP00000059081 ENSTRUP00000059081 ENSTRUP00000062106 ENSTRUP00000062106 LOC101066292 LOC101066292 LOC105418145 LOC105418145 pik3r3 pik3r3 LOC101069822 LOC101069822 pdlim7 pdlim7 ret ret LOC101075382 LOC101075382 LOC101062512 LOC101062512 LOC101067856 LOC101067856 LOC101065281 LOC101065281 LOC101062935 LOC101062935 ENSTRUP00000085490 ENSTRUP00000085490 NRTN NRTN shc4 shc4 fndc3b fndc3b frs2 frs2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTRUP00000081534Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1. (505 aa)
ENSTRUP00000001508GDNF family receptor alpha 2a. (405 aa)
GRB14Growth factor receptor bound protein 14. (528 aa)
LOC101066865GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (513 aa)
LOC101075115Uncharacterized protein. (452 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
dok6Docking protein 6. (332 aa)
pdlim5PDZ and LIM domain 5a. (450 aa)
LOC101069496Insulin receptor substrate 2b. (1096 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (1611 aa)
PSPNPersephin. (184 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
ENSTRUP00000078829Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (967 aa)
LOC101067369Growth factor receptor bound protein 7. (497 aa)
grb2Growth factor receptor-bound protein 2b. (220 aa)
LOC101076043Insulin receptor substrate 2a. (1054 aa)
SHC3SHC adaptor protein 3. (660 aa)
LOC101063692Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (736 aa)
LOC101067085GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (473 aa)
LOC101061527Uncharacterized protein. (465 aa)
gab2GRB2-associated binding protein 2. (679 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (253 aa)
LOC101074872GDNF family receptor alpha 4b. (434 aa)
gab1GRB2-associated binding protein 1. (749 aa)
LOC101073659Uncharacterized protein. (1693 aa)
LOC101079530Uncharacterized protein. (451 aa)
LOC101078435PH domain-containing protein. (744 aa)
srcTyrosine-protein kinase. (552 aa)
LOC101075301GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (457 aa)
LOC101061204Uncharacterized protein. (205 aa)
dok1Docking protein 1b. (652 aa)
LOC101067016Growth factor receptor-bound protein 10b. (630 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1147 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1040 aa)
LOC101064722Docking protein 2. (591 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (594 aa)
fndc3aFibronectin type III domain containing 3A. (1253 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
LOC101065244Uncharacterized protein. (730 aa)
shank3SH3 and multiple ankyrin repeat domains protein 3 isoform X1. (1985 aa)
ENSTRUP00000059081GDNF family receptor alpha 4a. (383 aa)
ENSTRUP00000062106SH3 and multiple ankyrin repeat domains protein 3-like isoform X1. (1683 aa)
LOC101066292Uncharacterized protein; Belongs to the protein kinase superfamily. (372 aa)
LOC105418145TGF_BETA_2 domain-containing protein. (300 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (497 aa)
LOC101069822Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (384 aa)
pdlim7PDZ and LIM domain 7. (424 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)
LOC101075382Growth factor receptor-bound protein 10a. (606 aa)
LOC101062512Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
LOC101067856Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (353 aa)
LOC101065281Tyrosine-protein kinase. (552 aa)
LOC101062935Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (385 aa)
ENSTRUP00000085490annotation not available (91 aa)
NRTNNeurturin. (234 aa)
shc4SHC-transforming protein 4 isoform X2. (470 aa)
fndc3bFibronectin type III domain containing 3Ba. (1224 aa)
frs2Fibroblast growth factor receptor substrate 2b. (1049 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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