14 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	LOC101074250	RAP1A, member of RAS oncogene family a. (185 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
	LOC101065989	CRK proto-oncogene, adaptor protein. (319 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1194 aa)
	LOC101078435	PH domain-containing protein. (744 aa)
	Dock7	Dedicator of cytokinesis 7; Belongs to the DOCK family. (2115 aa)
	LOC101061204	Uncharacterized protein. (205 aa)
	LOC101064935	Uncharacterized protein. (185 aa)
	LOC101070080	Uncharacterized protein. (184 aa)
	rap1a	Uncharacterized protein. (145 aa)
	met	Uncharacterized protein. (1425 aa)
	gab1	GRB2-associated binding protein 1. (749 aa)
	LOC101064315	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (756 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dock7	LOC101061204	ENSTRUP00000047368	ENSTRUP00000049272	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Uncharacterized protein.	0.414
Dock7	LOC101065989	ENSTRUP00000047368	ENSTRUP00000030297	Dedicator of cytokinesis 7; Belongs to the DOCK family.	CRK proto-oncogene, adaptor protein.	0.436
Dock7	LOC101078435	ENSTRUP00000047368	ENSTRUP00000044729	Dedicator of cytokinesis 7; Belongs to the DOCK family.	PH domain-containing protein.	0.417
Dock7	crkl	ENSTRUP00000047368	ENSTRUP00000009233	Dedicator of cytokinesis 7; Belongs to the DOCK family.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.436
Dock7	gab1	ENSTRUP00000047368	ENSTRUP00000035712	Dedicator of cytokinesis 7; Belongs to the DOCK family.	GRB2-associated binding protein 1.	0.417
Dock7	grb2	ENSTRUP00000047368	ENSTRUP00000020659	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Growth factor receptor-bound protein 2b.	0.414
Dock7	met	ENSTRUP00000047368	ENSTRUP00000078415	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Uncharacterized protein.	0.576
LOC101061204	Dock7	ENSTRUP00000049272	ENSTRUP00000047368	Uncharacterized protein.	Dedicator of cytokinesis 7; Belongs to the DOCK family.	0.414
LOC101061204	LOC101064315	ENSTRUP00000049272	ENSTRUP00000034166	Uncharacterized protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.461
LOC101061204	LOC101064935	ENSTRUP00000049272	ENSTRUP00000052446	Uncharacterized protein.	Uncharacterized protein.	0.556
LOC101061204	LOC101065989	ENSTRUP00000049272	ENSTRUP00000030297	Uncharacterized protein.	CRK proto-oncogene, adaptor protein.	0.755
LOC101061204	LOC101070080	ENSTRUP00000049272	ENSTRUP00000055897	Uncharacterized protein.	Uncharacterized protein.	0.556
LOC101061204	LOC101074250	ENSTRUP00000049272	ENSTRUP00000016335	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.556
LOC101061204	LOC101078435	ENSTRUP00000049272	ENSTRUP00000044729	Uncharacterized protein.	PH domain-containing protein.	0.990
LOC101061204	crkl	ENSTRUP00000049272	ENSTRUP00000009233	Uncharacterized protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.755
LOC101061204	gab1	ENSTRUP00000049272	ENSTRUP00000035712	Uncharacterized protein.	GRB2-associated binding protein 1.	0.990
LOC101061204	grb2	ENSTRUP00000049272	ENSTRUP00000020659	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.903
LOC101061204	met	ENSTRUP00000049272	ENSTRUP00000078415	Uncharacterized protein.	Uncharacterized protein.	0.938
LOC101061204	rap1a	ENSTRUP00000049272	ENSTRUP00000073508	Uncharacterized protein.	Uncharacterized protein.	0.556
LOC101061204	rapgef1	ENSTRUP00000049272	ENSTRUP00000046911	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.817