47 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	il7r	Uncharacterized protein. (436 aa)
	LOC101061159-2	CD81 antigen-like. (282 aa)
	LOC101064444	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
	c8b	Complement component 8, beta polypeptide. (591 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (648 aa)
	traf3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (614 aa)
	tlr5	TIR domain-containing protein; Belongs to the Toll-like receptor family. (884 aa)
	LOC105416219	MALT paracaspase 3. (589 aa)
	il6r	Fibronectin type-III domain-containing protein. (539 aa)
	LOC101080143	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...] (1023 aa)
	inpp5d	Inositol polyphosphate-5-phosphatase D. (1105 aa)
	tlr2	Toll-like receptor 2. (810 aa)
	cd40	CD40. (307 aa)
	plg	Uncharacterized protein; Belongs to the peptidase S1 family. (759 aa)
	cxcr4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	CSF3R	Colony stimulating factor 3 receptor. (818 aa)
	irf7	Interferon regulatory factor 7. (469 aa)
	cxcr5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	il1b	Interleukin-1; Belongs to the IL-1 family. (256 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
	RAC1	Uncharacterized protein. (214 aa)
	LOC101071242	Interleukin 10 receptor, beta. (407 aa)
	traf2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
	ccr7	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	tlr3	Toll-like receptor 3. (913 aa)
	irak4	Interleukin-1 receptor-associated kinase 4. (460 aa)
	cxcl14	Chemokine (C-X-C motif) ligand 14. (217 aa)
	c8g	Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family. (266 aa)
	LOC101067160	Rac family small GTPase 1b. (192 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	cd44	Link domain-containing protein. (357 aa)
	LOC105417801	Uncharacterized protein. (367 aa)
	masp2	Mannan-binding lectin serine peptidase 2. (303 aa)
	traf4	TNF receptor-associated factor. (470 aa)
	cd79a	CD79a molecule, immunoglobulin-associated alpha. (211 aa)
	LOC101078355	Toll interacting protein. (275 aa)
	LOC105418528	Uncharacterized protein. (1035 aa)
	LOC101061159	Tetraspanin. (239 aa)
	LOC101075779	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
	TOLLIP	Toll-interacting protein. (275 aa)
	cxcl12	Chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	LOC101069090	MALT paracaspase 2. (816 aa)
	malt1	MALT paracaspase 1. (836 aa)
	LOC101071398	Coagulation factor XIII, A1 polypeptide b. (794 aa)
	LOC101061773	Interleukin-1 receptor-associated kinase 1. (721 aa)
	csf1r	Macrophage colony-stimulating factor 1 receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...] (980 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSF3R	CXCR3	ENSTRUP00000028149	ENSTRUP00000083358	Colony stimulating factor 3 receptor.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.445
CSF3R	LOC101080143	ENSTRUP00000028149	ENSTRUP00000006673	Colony stimulating factor 3 receptor.	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	0.590
CSF3R	csf1r	ENSTRUP00000028149	ENSTRUP00000082354	Colony stimulating factor 3 receptor.	Macrophage colony-stimulating factor 1 receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	0.587
CSF3R	il6r	ENSTRUP00000028149	ENSTRUP00000007361	Colony stimulating factor 3 receptor.	Fibronectin type-III domain-containing protein.	0.758
CSF3R	il7r	ENSTRUP00000028149	ENSTRUP00000086252	Colony stimulating factor 3 receptor.	Uncharacterized protein.	0.630
CXCR3	CSF3R	ENSTRUP00000083358	ENSTRUP00000028149	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Colony stimulating factor 3 receptor.	0.445
CXCR3	ccr7	ENSTRUP00000083358	ENSTRUP00000048094	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.456
CXCR3	cd44	ENSTRUP00000083358	ENSTRUP00000051098	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Link domain-containing protein.	0.403
CXCR3	cxcl12	ENSTRUP00000083358	ENSTRUP00000074506	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.	0.813
CXCR3	cxcl14	ENSTRUP00000083358	ENSTRUP00000049733	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Chemokine (C-X-C motif) ligand 14.	0.526
CXCR3	cxcr4	ENSTRUP00000083358	ENSTRUP00000022640	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.600
CXCR3	cxcr5	ENSTRUP00000083358	ENSTRUP00000029841	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.497
CXCR3	il1b	ENSTRUP00000083358	ENSTRUP00000040920	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Interleukin-1; Belongs to the IL-1 family.	0.562
CXCR3	myd88	ENSTRUP00000083358	ENSTRUP00000050655	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.410
LOC101061159	LOC101067160	ENSTRUP00000061412	ENSTRUP00000050549	Tetraspanin.	Rac family small GTPase 1b.	0.411
LOC101061159	LOC105418528	ENSTRUP00000061412	ENSTRUP00000059013	Tetraspanin.	Uncharacterized protein.	0.492
LOC101061159	cd44	ENSTRUP00000061412	ENSTRUP00000051098	Tetraspanin.	Link domain-containing protein.	0.442
LOC101061159-2	LOC101067160	ENSTRUP00000087031	ENSTRUP00000050549	CD81 antigen-like.	Rac family small GTPase 1b.	0.411
LOC101061159-2	LOC105418528	ENSTRUP00000087031	ENSTRUP00000059013	CD81 antigen-like.	Uncharacterized protein.	0.492
LOC101061159-2	cd44	ENSTRUP00000087031	ENSTRUP00000051098	CD81 antigen-like.	Link domain-containing protein.	0.442