(10 nodes) (2021) Stimulus-Specific Expression, Selective Generation and Novel Function of Grass Carp (Ctenopharyngodon idella) IL-12 Isoforms: New Insights Into the Heterodimeric Cytokines in Teleosts. network (Takifugu rubripes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	stat3	Signal transducer and activator of transcription. (784 aa)
	LOC101068057	Signal transducer and activator of transcription. (737 aa)
	ENSTRUP00000072341	Dihydrofolate reductase. (187 aa)
	IL-17A/F-1	Interleukin-17A/F-1. (163 aa)
	tyk2	Tyrosine-protein kinase. (1144 aa)
	il10	Interleukin 10. (227 aa)
	LOC101068778	Tyrosine-protein kinase. (1125 aa)
	il1b	Interleukin-1; Belongs to the IL-1 family. (256 aa)
	tgf-beta1	Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (418 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL-17A/F-1	il10	ENSTRUP00000070034	ENSTRUP00000054385	Interleukin-17A/F-1.	Interleukin 10.	0.566
IL-17A/F-1	il1b	ENSTRUP00000070034	ENSTRUP00000040920	Interleukin-17A/F-1.	Interleukin-1; Belongs to the IL-1 family.	0.600
IL-17A/F-1	stat3	ENSTRUP00000070034	ENSTRUP00000056136	Interleukin-17A/F-1.	Signal transducer and activator of transcription.	0.445
LOC101068057	LOC101068778	ENSTRUP00000076351	ENSTRUP00000043195	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.900
LOC101068057	il10	ENSTRUP00000076351	ENSTRUP00000054385	Signal transducer and activator of transcription.	Interleukin 10.	0.472
LOC101068057	il1b	ENSTRUP00000076351	ENSTRUP00000040920	Signal transducer and activator of transcription.	Interleukin-1; Belongs to the IL-1 family.	0.461
LOC101068057	tyk2	ENSTRUP00000076351	ENSTRUP00000060023	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.935
LOC101068778	LOC101068057	ENSTRUP00000043195	ENSTRUP00000076351	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.900
LOC101068778	stat3	ENSTRUP00000043195	ENSTRUP00000056136	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.978
LOC101068778	tyk2	ENSTRUP00000043195	ENSTRUP00000060023	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.949
il10	IL-17A/F-1	ENSTRUP00000054385	ENSTRUP00000070034	Interleukin 10.	Interleukin-17A/F-1.	0.566
il10	LOC101068057	ENSTRUP00000054385	ENSTRUP00000076351	Interleukin 10.	Signal transducer and activator of transcription.	0.472
il10	il1b	ENSTRUP00000054385	ENSTRUP00000040920	Interleukin 10.	Interleukin-1; Belongs to the IL-1 family.	0.915
il10	myc	ENSTRUP00000054385	ENSTRUP00000022101	Interleukin 10.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.407
il10	stat3	ENSTRUP00000054385	ENSTRUP00000056136	Interleukin 10.	Signal transducer and activator of transcription.	0.647
il10	tgf-beta1	ENSTRUP00000054385	ENSTRUP00000040849	Interleukin 10.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.767
il10	tyk2	ENSTRUP00000054385	ENSTRUP00000060023	Interleukin 10.	Tyrosine-protein kinase.	0.452
il1b	IL-17A/F-1	ENSTRUP00000040920	ENSTRUP00000070034	Interleukin-1; Belongs to the IL-1 family.	Interleukin-17A/F-1.	0.600
il1b	LOC101068057	ENSTRUP00000040920	ENSTRUP00000076351	Interleukin-1; Belongs to the IL-1 family.	Signal transducer and activator of transcription.	0.461
il1b	il10	ENSTRUP00000040920	ENSTRUP00000054385	Interleukin-1; Belongs to the IL-1 family.	Interleukin 10.	0.915