STRINGSTRING
edn1 edn1 LOC101078125 LOC101078125 grk1 grk1 PXN PXN GRK1 GRK1 vcl vcl pik3cg pik3cg LOC101072042 LOC101072042 rho rho ednrb ednrb LOC101067191 LOC101067191 HDAC1 HDAC1 LOC778011 LOC778011 PIK3CA PIK3CA gapdh gapdh nox1 nox1 LOC619285 LOC619285 pkm pkm LOC445899 LOC445899 LOC446067 LOC446067 gapdh-2 gapdh-2 LOC101079163 LOC101079163 pxn pxn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
edn1Endothelin 1. (137 aa)
LOC101078125Sphingosine kinase 2. (889 aa)
grk1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (563 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (522 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (561 aa)
vclVinculin b. (1017 aa)
pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1127 aa)
LOC101072042Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
rhoRhodopsin. (353 aa)
ednrbEndothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (419 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HDAC1Histone deacetylase 1. (442 aa)
LOC778011Rhodopsin. (353 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
nox1FAD-binding FR-type domain-containing protein. (574 aa)
LOC619285Rhodopsin. (352 aa)
pkmPyruvate kinase; Belongs to the pyruvate kinase family. (578 aa)
LOC445899Pyruvate kinase; Belongs to the pyruvate kinase family. (563 aa)
LOC446067Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
gapdh-2Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
LOC101079163Rhodopsin. (349 aa)
pxnUncharacterized protein. (1106 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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