(20 nodes) Phospholipase C, catalytic domain (part) network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	plcl2	Phosphoinositide phospholipase C. (1108 aa)
	plcd1	Phosphoinositide phospholipase C. (827 aa)
	LOC101065481	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like. (1307 aa)
	LOC101078575	Phosphoinositide phospholipase C. (822 aa)
	plcd4	Phosphoinositide phospholipase C. (785 aa)
	plce1	Phospholipase C, epsilon 1. (2329 aa)
	LOC101078092	Phosphoinositide phospholipase C. (1213 aa)
	plch1	Phosphoinositide phospholipase C. (1881 aa)
	plch2	Phospholipase C eta 2. (1614 aa)
	plcl1	Phosphoinositide phospholipase C. (1183 aa)
	LOC101069591	PH_14 domain-containing protein. (1160 aa)
	LOC101066005	Phosphoinositide phospholipase C. (787 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
	PLCZ1	Phosphoinositide phospholipase C. (573 aa)
	plcd3	Phosphoinositide phospholipase C. (784 aa)
	LOC101071575	Phosphoinositide phospholipase C. (1210 aa)
	LOC101076439	Phosphoinositide phospholipase C. (1094 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1232 aa)
	plcg2	Phosphoinositide phospholipase C. (1248 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101065481	LOC101066005	ENSTRUP00000077824	ENSTRUP00000058292	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.771
LOC101065481	LOC101069591	ENSTRUP00000077824	ENSTRUP00000059163	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	PH_14 domain-containing protein.	0.684
LOC101065481	LOC101076439	ENSTRUP00000077824	ENSTRUP00000036231	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.432
LOC101065481	PLCB1	ENSTRUP00000077824	ENSTRUP00000074377	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.684
LOC101065481	PLCB4	ENSTRUP00000077824	ENSTRUP00000023269	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.684
LOC101065481	plcd1	ENSTRUP00000077824	ENSTRUP00000074581	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.771
LOC101065481	plcd3	ENSTRUP00000077824	ENSTRUP00000042343	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.771
LOC101065481	plcd4	ENSTRUP00000077824	ENSTRUP00000081452	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.771
LOC101065481	plce1	ENSTRUP00000077824	ENSTRUP00000082051	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phospholipase C, epsilon 1.	0.808
LOC101065481	plcg1	ENSTRUP00000077824	ENSTRUP00000058192	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.901
LOC101065481	plcg2	ENSTRUP00000077824	ENSTRUP00000017918	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.903
LOC101065481	plch1	ENSTRUP00000077824	ENSTRUP00000087432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phosphoinositide phospholipase C.	0.476
LOC101065481	plch2	ENSTRUP00000077824	ENSTRUP00000071111	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	Phospholipase C eta 2.	0.432
LOC101066005	LOC101065481	ENSTRUP00000058292	ENSTRUP00000077824	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	0.771
LOC101066005	LOC101069591	ENSTRUP00000058292	ENSTRUP00000059163	Phosphoinositide phospholipase C.	PH_14 domain-containing protein.	0.766
LOC101066005	LOC101076439	ENSTRUP00000058292	ENSTRUP00000036231	Phosphoinositide phospholipase C.	Phosphoinositide phospholipase C.	0.431
LOC101066005	PLCB1	ENSTRUP00000058292	ENSTRUP00000074377	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.761
LOC101066005	PLCB4	ENSTRUP00000058292	ENSTRUP00000023269	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.744
LOC101066005	plcd1	ENSTRUP00000058292	ENSTRUP00000074581	Phosphoinositide phospholipase C.	Phosphoinositide phospholipase C.	0.663
LOC101066005	plcd3	ENSTRUP00000058292	ENSTRUP00000042343	Phosphoinositide phospholipase C.	Phosphoinositide phospholipase C.	0.655