25 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tifa	Si:ch211-15b10.6. (193 aa)
	LOC101073185	FHA domain-containing protein. (1631 aa)
	nbn	Nibrin. (831 aa)
	KIF16B	Kinesin family member 16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1336 aa)
	ENSTRUP00000080659	annotation not available (237 aa)
	kif13a	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1893 aa)
	LOC101066561	Uncharacterized protein LOC101066561 isoform X1. (1325 aa)
	kif1b	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1818 aa)
	ENSTRUP00000072642	FHA domain-containing protein. (1211 aa)
	slmap	Sarcolemma associated protein. (898 aa)
	LOC101078769	PH domain-containing protein. (1399 aa)
	ppp1r8	Protein phosphatase 1, regulatory subunit 8b. (351 aa)
	LOC101075878	Marker of proliferation Ki-67. (1882 aa)
	tcf19	Transcription factor 19 (SC1), like. (547 aa)
	aggf1	Angiogenic factor with G patch and FHA domains 1. (684 aa)
	chek2	Checkpoint kinase 2. (538 aa)
	cep170b	Centrosomal protein 170B. (1621 aa)
	chfr	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (627 aa)
	foxk1	Forkhead box K1. (677 aa)
	kif14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1335 aa)
	slc4a1ap	Solute carrier family 4 member 1 adaptor protein. (794 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (473 aa)
	LOC101074946	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1812 aa)
	kif1a	Kinesin family member 1Ab; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1695 aa)
	foxk2	Uncharacterized protein. (642 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000080659	chek2	ENSTRUP00000080659	ENSTRUP00000035807	annotation not available	Checkpoint kinase 2.	0.654
ENSTRUP00000080659	rnf8	ENSTRUP00000080659	ENSTRUP00000014191	annotation not available	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.802
LOC101074946	kif14	ENSTRUP00000013782	ENSTRUP00000025219	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.477
LOC101074946	kif1a	ENSTRUP00000013782	ENSTRUP00000012452	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 1Ab; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
LOC101074946	kif1b	ENSTRUP00000013782	ENSTRUP00000073888	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
LOC101075878	kif14	ENSTRUP00000053078	ENSTRUP00000025219	Marker of proliferation Ki-67.	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.746
chek2	ENSTRUP00000080659	ENSTRUP00000035807	ENSTRUP00000080659	Checkpoint kinase 2.	annotation not available	0.654
chek2	rnf8	ENSTRUP00000035807	ENSTRUP00000014191	Checkpoint kinase 2.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.770
kif13a	kif14	ENSTRUP00000079078	ENSTRUP00000025219	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.477
kif13a	kif1a	ENSTRUP00000079078	ENSTRUP00000012452	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 1Ab; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
kif13a	kif1b	ENSTRUP00000079078	ENSTRUP00000073888	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
kif14	LOC101074946	ENSTRUP00000025219	ENSTRUP00000013782	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.477
kif14	LOC101075878	ENSTRUP00000025219	ENSTRUP00000053078	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Marker of proliferation Ki-67.	0.746
kif14	kif13a	ENSTRUP00000025219	ENSTRUP00000079078	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.477
kif1a	LOC101074946	ENSTRUP00000012452	ENSTRUP00000013782	Kinesin family member 1Ab; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
kif1a	kif13a	ENSTRUP00000012452	ENSTRUP00000079078	Kinesin family member 1Ab; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
kif1b	LOC101074946	ENSTRUP00000073888	ENSTRUP00000013782	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 13Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
kif1b	kif13a	ENSTRUP00000073888	ENSTRUP00000079078	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.478
rnf8	ENSTRUP00000080659	ENSTRUP00000014191	ENSTRUP00000080659	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	annotation not available	0.802
rnf8	chek2	ENSTRUP00000014191	ENSTRUP00000035807	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Checkpoint kinase 2.	0.770