STRINGSTRING
homer3 homer3 LOC101067063 LOC101067063 LOC101079262 LOC101079262 LOC101061984 LOC101061984 foxo3 foxo3 plk3 plk3 LOC101073562 LOC101073562 araf araf prkab1 prkab1 cdkn2d cdkn2d PIK3CA PIK3CA fbxo32 fbxo32 LOC101072756 LOC101072756 LOC101069496 LOC101069496 LOC101067191 LOC101067191 nlk nlk LOC101069736 LOC101069736 g6pc g6pc pik3cb pik3cb plk4 plk4 TGFBR2 TGFBR2 prkag3 prkag3 LOC101061973 LOC101061973 LOC101071000 LOC101071000 grb2 grb2 mdm2 mdm2 setd7 setd7 LOC101068373 LOC101068373 AKT2 AKT2 il-6 il-6 LOC101077955 LOC101077955 LOC101070065 LOC101070065 s1pr1 s1pr1 stk11 stk11 LOC101076043 LOC101076043 LOC101063692 LOC101063692 LOC101065438 LOC101065438 LOC101080220 LOC101080220 ccnb1 ccnb1 LOC101079677 LOC101079677 H2TZ36_TAKRU H2TZ36_TAKRU LOC101080225 LOC101080225 slc2a4 slc2a4 LOC101061527 LOC101061527 foxo4 foxo4 LOC101070901 LOC101070901 GADD45B GADD45B LOC101077171 LOC101077171 LOC101073984 LOC101073984 LOC101074584 LOC101074584 LOC101064978 LOC101064978 SOS1 SOS1 LOC101079603 LOC101079603 pdpk1 pdpk1 ccnd1 ccnd1 tgf-beta1 tgf-beta1 cat cat LOC101067377 LOC101067377 ikbkb ikbkb LOC101073915 LOC101073915 CCNG2 CCNG2 Prkag2 Prkag2 sirt1 sirt1 LOC101061036 LOC101061036 prkaa1 prkaa1 LOC101074300 LOC101074300 LOC101076880 LOC101076880 SMAD4 SMAD4 LOC101061204 LOC101061204 LOC101074416 LOC101074416 LOC101068020 LOC101068020 LOC101074788 LOC101074788 ENSTRUP00000050866 ENSTRUP00000050866 mapk1 mapk1 hras hras tgfb3 tgfb3 LOC101069368 LOC101069368 LOC101074744 LOC101074744 kras kras LOC101066787 LOC101066787 LOC101068466 LOC101068466 cdkn1b cdkn1b LOC101076205 LOC101076205 LOC101079162 LOC101079162 pik3cd pik3cd LOC101076354 LOC101076354 stat3 stat3 LOC101072794 LOC101072794 LOC101077778 LOC101077778 RAG2 RAG2 GADD45B-2 GADD45B-2 LOC101062282 LOC101062282 rag1 rag1 LOC101066563 LOC101066563 LOC101073575 LOC101073575 HOMER2 HOMER2 grm1 grm1 LOC105417819 LOC105417819 LOC101070190 LOC101070190 LOC101065671 LOC101065671 prmt1 prmt1 prkaa2 prkaa2 igf1 igf1 LOC101063427 LOC101063427 pik3r3 pik3r3 sos2 sos2 LOC101068125 LOC101068125 LOC101061688 LOC101061688 egfr egfr map2k2 map2k2 LOC115248448 LOC115248448 HOMER1 HOMER1 pck2 pck2 LOC101061420 LOC101061420 bcl6 bcl6 SGK1 SGK1 usp7 usp7 g6pc3 g6pc3 LOC101062512 LOC101062512 AGAP2 AGAP2 CHUK CHUK LOC101074083 LOC101074083 LOC101074212 LOC101074212 gadd45a gadd45a LOC101078548 LOC101078548 atg12 atg12 LOC101064045 LOC101064045 cdk2 cdk2 LOC101076947 LOC101076947 sgk3 sgk3 LOC101068225 LOC101068225 LOC101071408 LOC101071408 LOC101063351 LOC101063351 LOC101073734 LOC101073734 ENSTRUP00000081534 ENSTRUP00000081534 map2k1 map2k1 LOC101074428 LOC101074428 LOC101072654 LOC101072654 LOC101062695 LOC101062695 LOC101074026 LOC101074026 PRKAB2 PRKAB2 LOC101072628 LOC101072628 akt1 akt1 LOC101072519 LOC101072519 fbxo25 fbxo25 il7r il7r mapk10 mapk10 cdkn2A/B cdkn2A/B atm atm LOC101071975 LOC101071975
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
homer3Homer scaffold protein 3b. (358 aa)
LOC101067063WH1 domain-containing protein. (360 aa)
LOC101079262ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (845 aa)
LOC101061984Protein kinase domain-containing protein. (479 aa)
foxo3Forkhead box O3b. (659 aa)
plk3Serine/threonine-protein kinase PLK. (667 aa)
LOC101073562Cyclin D2, a; Belongs to the cyclin family. (296 aa)
arafUncharacterized protein. (597 aa)
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (299 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
fbxo32F-box protein 32. (395 aa)
LOC101072756Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (353 aa)
LOC101069496Insulin receptor substrate 2b. (1096 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (441 aa)
LOC101069736Zgc:55558. (187 aa)
g6pcGlucose-6-phosphatase a, catalytic subunit, tandem duplicate 2. (358 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
plk4Polo-like kinase 4 (Drosophila). (915 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
prkag3Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (391 aa)
LOC101061973Uncharacterized protein. (146 aa)
LOC101071000Phosphoenolpyruvate carboxykinase 1 (soluble). (623 aa)
grb2Growth factor receptor-bound protein 2b. (220 aa)
mdm2MDM2 proto-oncogene. (495 aa)
setd7SET domain containing 7, histone lysine methyltransferase. (370 aa)
LOC101068373Protein kinase domain-containing protein. (414 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
il-6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (227 aa)
LOC101077955Transforming growth factor beta; Belongs to the TGF-beta family. (406 aa)
LOC101070065Forkhead box O6 b. (729 aa)
s1pr1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
LOC101076043Insulin receptor substrate 2a. (1054 aa)
LOC101063692Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (736 aa)
LOC101065438Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC101080220Cyclin D2, b; Belongs to the cyclin family. (294 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (403 aa)
LOC101079677Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (426 aa)
H2TZ36_TAKRUFork-head domain-containing protein. (415 aa)
LOC101080225Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (412 aa)
slc2a4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (502 aa)
LOC101061527Uncharacterized protein. (465 aa)
foxo4Forkhead box O4. (648 aa)
LOC101070901Retinoblastoma-like 2 (p130). (1084 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (173 aa)
LOC101077171Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
LOC101073984CREB binding protein a. (3609 aa)
LOC101074584Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101064978TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (577 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1313 aa)
LOC101079603Tyrosine-protein kinase receptor. (1416 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (559 aa)
ccnd1Cyclin D1. (292 aa)
tgf-beta1Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (544 aa)
LOC101067377Mitogen-activated protein kinase. (408 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (736 aa)
LOC101073915Fork-head domain-containing protein. (647 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (334 aa)
Prkag2Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (325 aa)
sirt1Sirtuin 1. (689 aa)
LOC101061036Zgc:73226. (181 aa)
prkaa1Non-specific serine/threonine protein kinase. (572 aa)
LOC101074300Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (260 aa)
LOC101076880Zgc:92606. (117 aa)
SMAD4Mothers against decapentaplegic homolog. (521 aa)
LOC101061204Uncharacterized protein. (205 aa)
LOC101074416Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (391 aa)
LOC101068020CD40 ligand; Belongs to the tumor necrosis factor family. (232 aa)
LOC101074788Insulin receptor substrate 4a. (1378 aa)
ENSTRUP00000050866Uncharacterized protein. (177 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (404 aa)
LOC101069368Si:ch73-335l21.1. (1274 aa)
LOC101074744Uncharacterized protein. (386 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
LOC101066787Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC101068466Mothers against decapentaplegic homolog 4-like. (557 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
LOC101076205Cyclin B2; Belongs to the cyclin family. (416 aa)
LOC101079162Cyclin-dependent kinase inhibitor 1D. (181 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1040 aa)
LOC101076354Fork-head domain-containing protein. (382 aa)
stat3Signal transducer and activator of transcription. (784 aa)
LOC101072794Si:ch211-284e13.4. (1133 aa)
LOC101077778Cyclin G2; Belongs to the cyclin family. (331 aa)
RAG2Recombination-activating protein 2. (546 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (164 aa)
LOC101062282Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1086 aa)
LOC101066563Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC101073575Mitogen-activated protein kinase. (427 aa)
HOMER2Homer scaffold protein 2. (363 aa)
grm1Glutamate receptor, metabotropic 1a. (1170 aa)
LOC105417819Cyclin-dependent kinase inhibitor 1A. (205 aa)
LOC101070190Mitogen-activated protein kinase. (462 aa)
LOC101065671Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (385 aa)
prmt1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (367 aa)
prkaa2Non-specific serine/threonine protein kinase. (588 aa)
igf1IlGF domain-containing protein. (188 aa)
LOC101063427Tyrosine-protein kinase receptor. (1426 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (497 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1336 aa)
LOC101068125TPTEP2-CSNK1E readthrough; Belongs to the protein kinase superfamily. (459 aa)
LOC101061688Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (618 aa)
egfrReceptor protein-tyrosine kinase. (1189 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC115248448E1A binding protein p300 b. (2795 aa)
HOMER1Homer scaffold protein 1. (374 aa)
pck2Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (669 aa)
LOC101061420TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (283 aa)
bcl6Uncharacterized protein. (748 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (623 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1137 aa)
g6pc3Glucose 6 phosphatase, catalytic, 3. (335 aa)
LOC101062512Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1206 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (790 aa)
LOC101074083Tyrosine-protein kinase receptor. (1393 aa)
LOC101074212Homer scaffold protein 1b. (358 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, a. (162 aa)
LOC101078548Mitogen-activated protein kinase. (456 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
LOC101064045Mitogen-activated protein kinase. (383 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC101076947Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (163 aa)
sgk3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
LOC101068225Component of inhibitor of nuclear factor kappa B kinase complex. (741 aa)
LOC101071408Glutamate receptor, metabotropic 1b. (1166 aa)
LOC101063351Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (496 aa)
LOC101073734Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ENSTRUP00000081534Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1. (505 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC101074428Mitogen-activated protein kinase. (412 aa)
LOC101072654Uncharacterized protein. (660 aa)
LOC101062695Mitogen-activated protein kinase 12a. (361 aa)
LOC101074026Mitogen-activated protein kinase. (364 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (284 aa)
LOC101072628Forkhead box O1 a. (680 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
LOC101072519Fork-head domain-containing protein. (619 aa)
fbxo25F-box protein 25. (397 aa)
il7rUncharacterized protein. (436 aa)
mapk10Mitogen-activated protein kinase. (537 aa)
cdkn2A/BCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (133 aa)
atmTAN domain-containing protein. (3087 aa)
LOC101071975Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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