(104 nodes) Oocyte meiosis network (Takifugu rubripes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101063185	Uncharacterized protein; Belongs to the cyclin family. (380 aa)
	cdc27	Cell division cycle 27. (839 aa)
	adcy6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1246 aa)
	LOC101073369	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1178 aa)
	mos	V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily. (337 aa)
	LOC101064374	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (301 aa)
	LOC101070983	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (248 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (817 aa)
	LOC101077175	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1157 aa)
	LOC101067852	Uncharacterized protein. (678 aa)
	itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (2679 aa)
	smc3	Structural maintenance of chromosomes protein. (1162 aa)
	ccne2	Cyclin E2; Belongs to the cyclin family. (416 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	rps6ka6	Ribosomal protein S6 kinase. (700 aa)
	slk	STE20-like kinase a. (1142 aa)
	LOC101073968	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	LOC101074739	Inositol 1,4,5-trisphosphate receptor, type 1a. (2743 aa)
	LOC101071755	Uncharacterized protein. (2728 aa)
	LOC101071645	Ribosomal protein S6 kinase. (750 aa)
	LOC101068848	Cytoplasmic polyadenylation element binding protein 4a. (744 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	ccnb1	Cyclin B1; Belongs to the cyclin family. (403 aa)
	LOC101071292	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (178 aa)
	LOC101080066	Androgen receptor. (784 aa)
	LOC101069307	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (588 aa)
	LOC101079369	Cysteine three histidine 1. (317 aa)
	pgr	Progesterone receptor. (718 aa)
	aurka	Aurora kinase A; Belongs to the protein kinase superfamily. (418 aa)
	ywhaq	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
	smc1a	Structural maintenance of chromosomes protein. (1232 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (813 aa)
	bub1	BUB1 mitotic checkpoint serine/threonine kinase. (1153 aa)
	mad1l1	Mitotic arrest deficient 1 like 1. (719 aa)
	LOC101079603	Tyrosine-protein kinase receptor. (1416 aa)
	LOC101067377	Mitogen-activated protein kinase. (408 aa)
	anapc5	Anaphase promoting complex subunit 5. (770 aa)
	cpeb1	Cytoplasmic polyadenylation element binding protein 1b. (572 aa)
	calml4	Calmodulin-like 4a. (153 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (182 aa)
	sgo1	Shugoshin_C domain-containing protein. (654 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (620 aa)
	ppp1cb	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
	LOC101072182	Uncharacterized protein. (178 aa)
	LOC101074416	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (391 aa)
	spdya	Speedy/RINGO cell cycle regulator family member A. (314 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
	ENSTRUP00000052460	Ins145_P3_rec domain-containing protein. (206 aa)
	LOC101064018	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
	LOC101076205	Cyclin B2; Belongs to the cyclin family. (416 aa)
	calm2	Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	pkmyt1	Protein kinase, membrane associated tyrosine/threonine 1. (588 aa)
	LOC101063623	14_3_3 domain-containing protein. (245 aa)
	fbxo5	F-box protein 5. (438 aa)
	LOC101079903	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa)
	LOC101066563	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
	LOC101070452	Serine/threonine-protein phosphatase. (531 aa)
	espl1	Extra spindle pole bodies like 1, separase. (1956 aa)
	LOC101073266	Uncharacterized protein. (485 aa)
	H2RYE3_TAKRU	EF-hand domain-containing protein. (176 aa)
	LOC101071995	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2; Belongs to the protein kinase superfamily. (520 aa)
	LOC101065671	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (385 aa)
	LOC115248454	RING-box protein 1. (126 aa)
	LOC101071993	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (777 aa)
	LOC101066292	Uncharacterized protein; Belongs to the protein kinase superfamily. (372 aa)
	adcy1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	igf1	IlGF domain-containing protein. (188 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	LOC101063427	Tyrosine-protein kinase receptor. (1426 aa)
	anapc7	Anaphase promoting complex subunit 7. (567 aa)
	LOC101065632	G1/S-specific cyclin-E1-like isoform X1. (502 aa)
	YWHAE	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	LOC101072650	Serine/threonine-protein phosphatase. (520 aa)
	adcy5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1193 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (776 aa)
	anapc13	Anaphase promoting complex subunit 13. (74 aa)
	LOC101079814	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	LOC101070821	Ribosomal protein S6 kinase. (755 aa)
	ppp2r5c	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (598 aa)
	LOC101069822	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (384 aa)
	adcy7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC101074783	Serine/threonine-protein phosphatase. (532 aa)
	LOC101074943	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1156 aa)
	cpeb3	Cytoplasmic polyadenylation element binding protein 3. (669 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (619 aa)
	mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
	ywhaz	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (241 aa)
	LOC101077875	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (257 aa)
	LOC101067856	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (353 aa)
	ppp2r5a	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (531 aa)
	adcy3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1132 aa)
	LOC101064045	Mitogen-activated protein kinase. (383 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	LOC101067605	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1186 aa)
	LOC101078653	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	LOC101074428	Mitogen-activated protein kinase. (412 aa)
	LOC101062695	Mitogen-activated protein kinase 12a. (361 aa)
	LOC101074026	Mitogen-activated protein kinase. (364 aa)
	LOC115251941	Cyclin E1; Belongs to the cyclin family. (502 aa)
	ppp2r5e	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa)
	LOC101073390	Guanylate cyclase domain-containing protein. (1182 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPEB4	LOC101064374	ENSTRUP00000067023	ENSTRUP00000007140	Cytoplasmic polyadenylation element binding protein 4.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.905
CPEB4	LOC101065671	ENSTRUP00000067023	ENSTRUP00000061681	Cytoplasmic polyadenylation element binding protein 4.	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	0.903
CPEB4	LOC101074416	ENSTRUP00000067023	ENSTRUP00000049485	Cytoplasmic polyadenylation element binding protein 4.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.903
CPEB4	LOC101076205	ENSTRUP00000067023	ENSTRUP00000053618	Cytoplasmic polyadenylation element binding protein 4.	Cyclin B2; Belongs to the cyclin family.	0.903
CPEB4	aurka	ENSTRUP00000067023	ENSTRUP00000033876	Cytoplasmic polyadenylation element binding protein 4.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.911
CPEB4	mos	ENSTRUP00000067023	ENSTRUP00000006765	Cytoplasmic polyadenylation element binding protein 4.	V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily.	0.434
ENSTRUP00000052460	H2RYE3_TAKRU	ENSTRUP00000052460	ENSTRUP00000059292	Ins145_P3_rec domain-containing protein.	EF-hand domain-containing protein.	0.916
ENSTRUP00000052460	LOC101066292	ENSTRUP00000052460	ENSTRUP00000063491	Ins145_P3_rec domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	LOC101067856	ENSTRUP00000052460	ENSTRUP00000076783	Ins145_P3_rec domain-containing protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	LOC101069822	ENSTRUP00000052460	ENSTRUP00000070462	Ins145_P3_rec domain-containing protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	calm2	ENSTRUP00000052460	ENSTRUP00000054207	Ins145_P3_rec domain-containing protein.	Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.	0.927
ENSTRUP00000052460	calml4	ENSTRUP00000052460	ENSTRUP00000042758	Ins145_P3_rec domain-containing protein.	Calmodulin-like 4a.	0.916
H2RYE3_TAKRU	ENSTRUP00000052460	ENSTRUP00000059292	ENSTRUP00000052460	EF-hand domain-containing protein.	Ins145_P3_rec domain-containing protein.	0.916
H2RYE3_TAKRU	LOC101064018	ENSTRUP00000059292	ENSTRUP00000052883	EF-hand domain-containing protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.740
H2RYE3_TAKRU	LOC101070452	ENSTRUP00000059292	ENSTRUP00000057879	EF-hand domain-containing protein.	Serine/threonine-protein phosphatase.	0.935
H2RYE3_TAKRU	LOC101071292	ENSTRUP00000059292	ENSTRUP00000031163	EF-hand domain-containing protein.	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.	0.922
H2RYE3_TAKRU	LOC101071755	ENSTRUP00000059292	ENSTRUP00000024995	EF-hand domain-containing protein.	Uncharacterized protein.	0.916
H2RYE3_TAKRU	LOC101071995	ENSTRUP00000059292	ENSTRUP00000060090	EF-hand domain-containing protein.	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2; Belongs to the protein kinase superfamily.	0.941
H2RYE3_TAKRU	LOC101072650	ENSTRUP00000059292	ENSTRUP00000066842	EF-hand domain-containing protein.	Serine/threonine-protein phosphatase.	0.935
H2RYE3_TAKRU	LOC101073266	ENSTRUP00000059292	ENSTRUP00000059265	EF-hand domain-containing protein.	Uncharacterized protein.	0.935