STRINGSTRING
LOC101072673 LOC101072673 LOC101066261 LOC101066261 LOC101066490 LOC101066490 LOC101075512 LOC101075512 ctsd2 ctsd2 LOC101072522 LOC101072522 LOC115249985 LOC115249985 H2RZ55_TAKRU H2RZ55_TAKRU parp3 parp3 LOC101067511 LOC101067511 LOC101064143 LOC101064143 PIK3CA PIK3CA tnfrsf1a tnfrsf1a lmnb1 lmnb1 H2SIR7_TAKRU H2SIR7_TAKRU LOC101073909 LOC101073909 LOC101068795 LOC101068795 tnfa tnfa itpr2 itpr2 LOC101064444 LOC101064444 LOC101067191 LOC101067191 LOC101069736 LOC101069736 ctsc ctsc LOC101062460 LOC101062460 pik3cb pik3cb LOC101066041 LOC101066041 LOC101075977 LOC101075977 LOC101064754 LOC101064754 LOC101064467 LOC101064467 LOC101063922 LOC101063922 AKT2 AKT2 casp6 casp6 LOC101075191 LOC101075191 casp8 casp8 LOC101074739 LOC101074739 LOC101071755 LOC101071755 LOC101071039 LOC101071039 LOC101068404 LOC101068404 LOC101063692 LOC101063692 LOC101065438 LOC101065438 LOC101078177 LOC101078177 parp2 parp2 ripk1 ripk1 LOC101061527 LOC101061527 LOC101077542 LOC101077542 LOC101079595 LOC101079595 LOC101070919 LOC101070919 cflar cflar LOC101069689 LOC101069689 LOC101076595 LOC101076595 GADD45B GADD45B ntrk1 ntrk1 LOC101077171 LOC101077171 ctsz ctsz LOC101068369 LOC101068369 ENSTRUP00000036531 ENSTRUP00000036531 H2UHW1_TAKRU H2UHW1_TAKRU casp2 casp2 pdpk1 pdpk1 CASP3 CASP3 LOC101076903 LOC101076903 ikbkb ikbkb LOC101062741 LOC101062741 LOC101075537 LOC101075537 casp9 casp9 eif2s1 eif2s1 tradd tradd LOC101076370 LOC101076370 LOC101067832 LOC101067832 LOC101074300 LOC101074300 LOC101074856 LOC101074856 traf2 traf2 LOC101061790 LOC101061790 LOC101064682 LOC101064682 LOC101077059 LOC101077059 LOC101075957 LOC101075957 LOC101067442 LOC101067442 LOC101079871 LOC101079871 parp1 parp1 LOC101068020 LOC101068020 ddit3 ddit3 LOC101074770 LOC101074770 LOC105418899 LOC105418899 LOC101068711 LOC101068711 LOC101064478 LOC101064478 htra2 htra2 dffa dffa mapk1 mapk1 hras hras ENSTRUP00000052460 ENSTRUP00000052460 bax bax kras kras LOC101077993 LOC101077993 LOC101067763 LOC101067763 c-JunL c-JunL dab2ip dab2ip pik3cd pik3cd LOC101067333 LOC101067333 LOC101061990 LOC101061990 ctsl ctsl ctso ctso casp7 casp7 GADD45B-2 GADD45B-2 LOC101066563 LOC101066563 LOC101073575 LOC101073575 LOC101067048 LOC101067048 LOC101074678 LOC101074678 nfkb1 nfkb1 LOC101070190 LOC101070190 LOC101067067 LOC101067067 LOC101075779 LOC101075779 apaf1 apaf1 ptpn13 ptpn13 LOC101076659 LOC101076659 pik3r3 pik3r3 LOC101064386 LOC101064386 LOC101077373 LOC101077373 sptan1 sptan1 map2k2 map2k2 LOC101067596 LOC101067596 Parp4 Parp4 LOC101070832 LOC101070832 LOC101061420 LOC101061420 LOC101062512 LOC101062512 lmnb2 lmnb2 LOC101062648 LOC101062648 nfkbia nfkbia CHUK CHUK tnfrsf1a-2 tnfrsf1a-2 LMNA LMNA map3k5 map3k5 LOC101072310 LOC101072310 LOC101073743 LOC101073743 gadd45a gadd45a LOC101076691 LOC101076691 atf4 atf4 ENSTRUP00000077943 ENSTRUP00000077943 LOC101078548 LOC101078548 LOC101062302 LOC101062302 LOC101073992 LOC101073992 LOC101076947 LOC101076947 LOC101068225 LOC101068225 LOC105418743 LOC105418743 LOC101073734 LOC101073734 ENSTRUP00000081534 ENSTRUP00000081534 map2k1 map2k1 ern1 ern1 akt1 akt1 ENSTRUP00000084969 ENSTRUP00000084969 LOC101072129 LOC101072129 LOC101069436 LOC101069436 LOC101069964 LOC101069964 mapk10 mapk10 CTSD1 CTSD1 atm atm LOC101071975 LOC101071975
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101072673Tubulin alpha-1B chain-like. (463 aa)
LOC101066261Cathepsin K; Belongs to the peptidase C1 family. (331 aa)
LOC101066490Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (334 aa)
LOC101075512Uncharacterized protein. (703 aa)
ctsd2Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (386 aa)
LOC101072522Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (509 aa)
LOC115249985Perforin 1.3. (576 aa)
H2RZ55_TAKRUBH4_2 domain-containing protein. (165 aa)
parp3Poly [ADP-ribose] polymerase. (528 aa)
LOC101067511Zgc:153993. (202 aa)
LOC101064143Lamin L3; Belongs to the intermediate filament family. (593 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (378 aa)
lmnb1Lamin B1; Belongs to the intermediate filament family. (584 aa)
H2SIR7_TAKRUBH4_2 domain-containing protein. (215 aa)
LOC101073909Cathepsin S, ortholog 1; Belongs to the peptidase C1 family. (337 aa)
LOC101068795Uncharacterized protein. (538 aa)
tnfaTumor necrosis factor alpha. (250 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2679 aa)
LOC101064444TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101069736Zgc:55558. (187 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (462 aa)
LOC101062460Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
LOC101066041Diablo, IAP-binding mitochondrial protein a. (237 aa)
LOC101075977Cathepsin F; Belongs to the peptidase C1 family. (476 aa)
LOC101064754Uncharacterized protein; Belongs to the peptidase C2 family. (700 aa)
LOC101064467Perforin 1.9. (587 aa)
LOC101063922Zgc:55262; Belongs to the peptidase C2 family. (786 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (303 aa)
LOC101075191Uncharacterized protein; Belongs to the peptidase C14A family. (388 aa)
casp8Uncharacterized protein; Belongs to the peptidase C14A family. (526 aa)
LOC101074739Inositol 1,4,5-trisphosphate receptor, type 1a. (2743 aa)
LOC101071755Uncharacterized protein. (2728 aa)
LOC101071039Si:ch211-1i11.3. (1324 aa)
LOC101068404Si:ch211-153j24.3. (378 aa)
LOC101063692Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (736 aa)
LOC101065438Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC101078177Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). (389 aa)
parp2Poly [ADP-ribose] polymerase. (643 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (661 aa)
LOC101061527Uncharacterized protein. (465 aa)
LOC101077542Cathepsin L.1; Belongs to the peptidase C1 family. (337 aa)
LOC101079595Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
LOC101070919Cathepsin Bb; Belongs to the peptidase C1 family. (328 aa)
cflarUncharacterized protein; Belongs to the peptidase C14A family. (470 aa)
LOC101069689BH4_2 domain-containing protein. (218 aa)
LOC101076595Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (701 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (173 aa)
ntrk1Tyrosine-protein kinase receptor. (624 aa)
LOC101077171Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
LOC101068369Mitogen-activated protein kinase kinase kinase 14a. (887 aa)
ENSTRUP00000036531Bcl-2-like 1 (apoptosis regulator Bcl-X). (211 aa)
H2UHW1_TAKRUBH4_2 domain-containing protein. (209 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (449 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (559 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (280 aa)
LOC101076903Cathepsin 12; Belongs to the peptidase C1 family. (361 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (736 aa)
LOC101062741Baculoviral IAP repeat containing 5a. (142 aa)
LOC101075537Baculoviral IAP repeat containing 2. (639 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (432 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
traddTnfrsf1a-associated via death domain. (305 aa)
LOC101076370Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (190 aa)
LOC101067832V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (379 aa)
LOC101074300Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (260 aa)
LOC101074856Uncharacterized protein; Belongs to the peptidase C14A family. (275 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
LOC101061790Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
LOC101064682Baculoviral IAP repeat containing 5b. (152 aa)
LOC101077059Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
LOC101075957Activating transcription factor 4b. (433 aa)
LOC101067442Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (557 aa)
LOC101079871Tubulin alpha chain-like. (474 aa)
parp1Poly [ADP-ribose] polymerase. (1047 aa)
LOC101068020CD40 ligand; Belongs to the tumor necrosis factor family. (232 aa)
ddit3DNA-damage-inducible transcript 3. (309 aa)
LOC101074770Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa)
LOC105418899IL2RB_N1 domain-containing protein. (553 aa)
LOC101068711Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
LOC101064478Diablo, IAP-binding mitochondrial protein a. (258 aa)
htra2Si:dkey-33c12.12. (443 aa)
dffaDNA fragmentation factor, alpha polypeptide. (287 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSTRUP00000052460Ins145_P3_rec domain-containing protein. (206 aa)
baxBCL2 associated X, apoptosis regulator a. (193 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
LOC101077993Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC101067763Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
c-JunLC-JunL protein; Belongs to the bZIP family. (293 aa)
dab2ipDAB2 interacting protein b. (1250 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1040 aa)
LOC101067333Cytochrome c-a; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
LOC101061990Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ctslSi:dkey-26g8.5; Belongs to the peptidase C1 family. (350 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (337 aa)
casp7Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (315 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (164 aa)
LOC101066563Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC101073575Mitogen-activated protein kinase. (427 aa)
LOC101067048Endoplasmic reticulum to nucleus signaling 2. (1011 aa)
LOC101074678Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (484 aa)
nfkb1Nuclear factor NF-kappa-B p105 subunit. (1506 aa)
LOC101070190Mitogen-activated protein kinase. (462 aa)
LOC101067067DED domain-containing protein. (196 aa)
LOC101075779TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
apaf1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1292 aa)
ptpn13Protein tyrosine phosphatase non-receptor type 13. (2550 aa)
LOC101076659Cathepsin Ba; Belongs to the peptidase C1 family. (337 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (497 aa)
LOC101064386Cytochrome c-b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
LOC101077373Lamin A; Belongs to the intermediate filament family. (675 aa)
sptan1Uncharacterized protein. (2479 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC101067596Mitogen-activated protein kinase kinase kinase 14. (933 aa)
Parp4Uncharacterized protein. (1927 aa)
LOC101070832Uncharacterized protein; Belongs to the peptidase C2 family. (765 aa)
LOC101061420TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (283 aa)
LOC101062512Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
lmnb2Lamin B2; Belongs to the intermediate filament family. (587 aa)
LOC101062648Perforin 1.5. (549 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (790 aa)
tnfrsf1a-2Tumor necrosis factor receptor superfamily, member 1a. (378 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (648 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1350 aa)
LOC101072310Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (314 aa)
LOC101073743V-rel avian reticuloendotheliosis viral oncogene homolog A. (626 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, a. (162 aa)
LOC101076691BCL2 like 1. (218 aa)
atf4Activating transcription factor 4a. (442 aa)
ENSTRUP00000077943Disabled homolog 2-interacting protein-like isoform X1. (1037 aa)
LOC101078548Mitogen-activated protein kinase. (456 aa)
LOC101062302Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
LOC101073992Uncharacterized protein. (456 aa)
LOC101076947Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (163 aa)
LOC101068225Component of inhibitor of nuclear factor kappa B kinase complex. (741 aa)
LOC105418743BCL2 associated agonist of cell death b. (168 aa)
LOC101073734Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ENSTRUP00000081534Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1. (505 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1017 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
ENSTRUP00000084969Perforin-1-like. (497 aa)
LOC101072129Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
LOC101069436MCL1 apoptosis regulator, BCL2 family member b. (272 aa)
LOC101069964Uncharacterized protein. (202 aa)
mapk10Mitogen-activated protein kinase. (537 aa)
CTSD1Cathepsin D1; Belongs to the peptidase A1 family. (416 aa)
atmTAN domain-containing protein. (3087 aa)
LOC101071975Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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