STRINGSTRING
PIK3CA PIK3CA ptgs2 ptgs2 nfatc2 nfatc2 LOC101067191 LOC101067191 LOC101069736 LOC101069736 pik3cb pik3cb plcg2 plcg2 LOC101070662 LOC101070662 AKT2 AKT2 shc2 shc2 MAPKAPK3 MAPKAPK3 LOC101065234 LOC101065234 LOC101063692 LOC101063692 LOC101065438 LOC101065438 SPHK1 SPHK1 LOC101061527 LOC101061527 LOC101071292 LOC101071292 LOC101065347 LOC101065347 PXN PXN H2UWV7_TAKRU H2UWV7_TAKRU LOC101067377 LOC101067377 RAC1 RAC1 casp9 casp9 LOC101068861 LOC101068861 src src LOC101067160 LOC101067160 mapk1 mapk1 hras hras LOC101078125 LOC101078125 kras kras pik3cd pik3cd mapkapk2 mapkapk2 pxn pxn vegfb vegfb LOC101066563 LOC101066563 LOC101070452 LOC101070452 plcg1 plcg1 LOC101073266 LOC101073266 LOC101066672 LOC101066672 LOC101064815 LOC101064815 PRKCB PRKCB ENSTRUP00000064457 ENSTRUP00000064457 pik3r3 pik3r3 LOC101072650 LOC101072650 map2k2 map2k2 LOC101074783 LOC101074783 LOC101062512 LOC101062512 ENSTRUP00000075091 ENSTRUP00000075091 kdr kdr LOC101065481 LOC101065481 LOC101067723 LOC101067723 LOC101064045 LOC101064045 LOC105418743 LOC105418743 LOC101068145 LOC101068145 LOC101073734 LOC101073734 ENSTRUP00000081534 ENSTRUP00000081534 map2k1 map2k1 LOC101074428 LOC101074428 LOC101062695 LOC101062695 LOC101074026 LOC101074026 LOC101065281 LOC101065281 akt1 akt1 LOC101079823 LOC101079823 hspb1 hspb1 rac2 rac2 LOC101071975 LOC101071975
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ptgs2Prostaglandin-endoperoxide synthase 2b. (617 aa)
nfatc2Nuclear factor of activated T cells 2a. (884 aa)
LOC101067191Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101069736Zgc:55558. (187 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
plcg2Phosphoinositide phospholipase C. (1248 aa)
LOC101070662PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (718 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (404 aa)
LOC101065234Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC101063692Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (736 aa)
LOC101065438Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SPHK1Sphingosine kinase 1. (565 aa)
LOC101061527Uncharacterized protein. (465 aa)
LOC101071292Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (178 aa)
LOC101065347PLA2c domain-containing protein. (326 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (522 aa)
H2UWV7_TAKRUSHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (126 aa)
LOC101067377Mitogen-activated protein kinase. (408 aa)
RAC1Uncharacterized protein. (214 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (432 aa)
LOC101068861RHD domain-containing protein. (875 aa)
srcTyrosine-protein kinase. (552 aa)
LOC101067160Rac family small GTPase 1b. (192 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC101078125Sphingosine kinase 2. (889 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1040 aa)
mapkapk2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (383 aa)
pxnUncharacterized protein. (1106 aa)
vegfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (258 aa)
LOC101066563Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC101070452Serine/threonine-protein phosphatase. (531 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
LOC101073266Uncharacterized protein. (485 aa)
LOC101066672MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (401 aa)
LOC101064815Protein kinase C. (687 aa)
PRKCBNon-specific serine/threonine protein kinase. (682 aa)
ENSTRUP00000064457Ras-related C3 botulinum toxin substrate 3 isoform X1. (218 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (497 aa)
LOC101072650Serine/threonine-protein phosphatase. (520 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC101074783Serine/threonine-protein phosphatase. (532 aa)
LOC101062512Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
ENSTRUP00000075091Cytosolic phospholipase A2 gamma-like. (545 aa)
kdrKinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1365 aa)
LOC1010654811-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like. (1307 aa)
LOC101067723Cell division cycle 42. (191 aa)
LOC101064045Mitogen-activated protein kinase. (383 aa)
LOC105418743BCL2 associated agonist of cell death b. (168 aa)
LOC101068145Uncharacterized protein. (191 aa)
LOC101073734Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ENSTRUP00000081534Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1. (505 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC101074428Mitogen-activated protein kinase. (412 aa)
LOC101062695Mitogen-activated protein kinase 12a. (361 aa)
LOC101074026Mitogen-activated protein kinase. (364 aa)
LOC101065281Tyrosine-protein kinase. (552 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
LOC101079823Classical protein kinase C gamma type. (700 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (200 aa)
rac2Rac family small GTPase 2. (218 aa)
LOC101071975Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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