100 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101072673	Tubulin alpha-1B chain-like. (463 aa)
	map3k2	Mitogen-activated protein kinase kinase kinase 2. (613 aa)
	LOC101076768	Uncharacterized protein. (359 aa)
	LOC101077978	Guanine nucleotide binding protein (G protein), alpha 14. (354 aa)
	adcy6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1246 aa)
	LOC101073369	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1178 aa)
	LOC101063539	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (200 aa)
	LOC101064374	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (301 aa)
	LOC101070302	D(1)-like dopamine receptor; Receptor for dopamine; Belongs to the G-protein coupled receptor 1 family. (459 aa)
	LOC101075588	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	LOC101061130	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1025 aa)
	LOC101077175	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1157 aa)
	LOC101063263	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (306 aa)
	itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (2679 aa)
	LOC101069736	Zgc:55558. (187 aa)
	LOC101062460	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
	LOC101061293	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (433 aa)
	GUCY1A2	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (798 aa)
	pdgfrb	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...] (1129 aa)
	grb2	Growth factor receptor-bound protein 2b. (220 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1232 aa)
	LOC101065234	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
	LOC101074739	Inositol 1,4,5-trisphosphate receptor, type 1a. (2743 aa)
	LOC101071755	Uncharacterized protein. (2728 aa)
	LOC101080197	Uncharacterized protein. (354 aa)
	adrb1	Adrenoceptor beta 1. (455 aa)
	LOC101065996	GNAS complex locus. (379 aa)
	LOC101072579	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (469 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1313 aa)
	gucy1a1	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (675 aa)
	GJD2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
	drd2	D(2)-like dopamine receptor; Receptor for dopamine; Belongs to the G-protein coupled receptor 1 family. (463 aa)
	pdgfc	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
	LOC101064713	Uncharacterized protein. (368 aa)
	LOC101069449	Tight junction protein 1a; Belongs to the MAGUK family. (1781 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (471 aa)
	src	Tyrosine-protein kinase. (552 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (542 aa)
	LOC101061790	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
	LOC101067442	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (557 aa)
	LOC101079871	Tubulin alpha chain-like. (474 aa)
	LOC101061204	Uncharacterized protein. (205 aa)
	gja1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (293 aa)
	LOC101072775	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (580 aa)
	LOC101074770	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa)
	LOC101074285	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	ENSTRUP00000052460	Ins145_P3_rec domain-containing protein. (206 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1147 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
	LOC101068452	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
	LOC101067763	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	LOC101061990	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	LOC101066563	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
	Pdgfd	Platelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family. (334 aa)
	LOC101074678	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (484 aa)
	LOC101069591	PH_14 domain-containing protein. (1160 aa)
	grm1	Glutamate receptor, metabotropic 1a. (1170 aa)
	LOC101066291	Uncharacterized protein. (359 aa)
	LOC101064815	Protein kinase C. (687 aa)
	grm5	Glutamate receptor, metabotropic 5b. (1229 aa)
	PRKCB	Non-specific serine/threonine protein kinase. (682 aa)
	gnas	Uncharacterized protein. (392 aa)
	LOC101066292	Uncharacterized protein; Belongs to the protein kinase superfamily. (372 aa)
	adcy1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	LOC101069201	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (432 aa)
	sos2	Son of sevenless homolog 2 (Drosophila). (1336 aa)
	adcy5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1193 aa)
	egfr	Receptor protein-tyrosine kinase. (1189 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	PRKG1	Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (691 aa)
	ENSTRUP00000069361	Tubulin beta chain-like. (100 aa)
	FrGCS-beta1	Soluble guanylyl cyclase beta1 subunit; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (648 aa)
	LOC101069822	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (384 aa)
	adcy7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
	LOC101074943	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1156 aa)
	ENSTRUP00000071237	CGMP-dependent protein kinase 2-like. (735 aa)
	LOC101062287	Tubulin domain-containing protein. (453 aa)
	pdgfra	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...] (1499 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1247 aa)
	ENSTRUP00000075210	Guanylate cyclase soluble subunit beta-1-like. (582 aa)
	LOC101072310	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (314 aa)
	LOC101067856	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (353 aa)
	LOC101062302	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
	adcy3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1132 aa)
	LOC101079922	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (412 aa)
	LOC101071408	Glutamate receptor, metabotropic 1b. (1166 aa)
	LOC101067605	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1186 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	csnk1d	Casein kinase 1, delta b; Belongs to the protein kinase superfamily. (405 aa)
	tubb	Tubulin domain-containing protein. (451 aa)
	LOC101077225	Tubulin, beta 6 class V. (446 aa)
	LOC101065281	Tyrosine-protein kinase. (552 aa)
	LOC101079823	Classical protein kinase C gamma type. (700 aa)
	LOC101068084	G_PROTEIN_RECEP_F1_2 domain-containing protein. (395 aa)
	LOC101073390	Guanylate cyclase domain-containing protein. (1182 aa)
	LOC101065811	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (486 aa)
	prkg2	AGC-kinase C-terminal domain-containing protein. (775 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000052460	LOC101064815	ENSTRUP00000052460	ENSTRUP00000061887	Ins145_P3_rec domain-containing protein.	Protein kinase C.	0.910
ENSTRUP00000052460	LOC101065234	ENSTRUP00000052460	ENSTRUP00000024076	Ins145_P3_rec domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.910
ENSTRUP00000052460	LOC101066292	ENSTRUP00000052460	ENSTRUP00000063491	Ins145_P3_rec domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	LOC101067856	ENSTRUP00000052460	ENSTRUP00000076783	Ins145_P3_rec domain-containing protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	LOC101069591	ENSTRUP00000052460	ENSTRUP00000059163	Ins145_P3_rec domain-containing protein.	PH_14 domain-containing protein.	0.925
ENSTRUP00000052460	LOC101069822	ENSTRUP00000052460	ENSTRUP00000070462	Ins145_P3_rec domain-containing protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.944
ENSTRUP00000052460	LOC101079823	ENSTRUP00000052460	ENSTRUP00000085876	Ins145_P3_rec domain-containing protein.	Classical protein kinase C gamma type.	0.910
ENSTRUP00000052460	PLCB1	ENSTRUP00000052460	ENSTRUP00000074377	Ins145_P3_rec domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.925
ENSTRUP00000052460	PLCB4	ENSTRUP00000052460	ENSTRUP00000023269	Ins145_P3_rec domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.927
ENSTRUP00000052460	PRKCB	ENSTRUP00000052460	ENSTRUP00000063174	Ins145_P3_rec domain-containing protein.	Non-specific serine/threonine protein kinase.	0.910
ENSTRUP00000069361	LOC101061790	ENSTRUP00000069361	ENSTRUP00000048378	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882
ENSTRUP00000069361	LOC101061990	ENSTRUP00000069361	ENSTRUP00000054721	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.883
ENSTRUP00000069361	LOC101062302	ENSTRUP00000069361	ENSTRUP00000078816	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882
ENSTRUP00000069361	LOC101062460	ENSTRUP00000069361	ENSTRUP00000016807	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.884
ENSTRUP00000069361	LOC101067442	ENSTRUP00000069361	ENSTRUP00000048935	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882
ENSTRUP00000069361	LOC101067763	ENSTRUP00000069361	ENSTRUP00000053820	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882
ENSTRUP00000069361	LOC101072310	ENSTRUP00000069361	ENSTRUP00000075687	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.927
ENSTRUP00000069361	LOC101072673	ENSTRUP00000069361	ENSTRUP00000000266	Tubulin beta chain-like.	Tubulin alpha-1B chain-like.	0.882
ENSTRUP00000069361	LOC101074678	ENSTRUP00000069361	ENSTRUP00000059010	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882
ENSTRUP00000069361	LOC101074770	ENSTRUP00000069361	ENSTRUP00000050280	Tubulin beta chain-like.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.882