107 items (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stat1	Signal transducer and activator of transcription. (763 aa)
	ENSTRUP00000000520	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (668 aa)
	cblb	Cbl proto-oncogene B, E3 ubiquitin protein ligase. (949 aa)
	egr2	Early growth response 2b. (430 aa)
	plk3	Serine/threonine-protein kinase PLK. (667 aa)
	egr3	Early growth response 3. (412 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (617 aa)
	LOC101075171	Interferon regulatory factor. (308 aa)
	LOC105416219	MALT paracaspase 3. (589 aa)
	pak1	Non-specific serine/threonine protein kinase. (562 aa)
	LOC101062626	Uncharacterized protein; Belongs to the peptidase C14A family. (382 aa)
	mras	Muscle RAS oncogene homolog. (208 aa)
	tnfa	Tumor necrosis factor alpha. (250 aa)
	itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (2679 aa)
	nfatc2	Nuclear factor of activated T cells 2a. (884 aa)
	LOC101067191	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101069736	Zgc:55558. (187 aa)
	pik3cb	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)
	plcg2	Phosphoinositide phospholipase C. (1248 aa)
	LOC101064415	Uncharacterized protein; Belongs to the peptidase C14A family. (384 aa)
	mdm2	MDM2 proto-oncogene. (495 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	il-6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (227 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (359 aa)
	LOC101075191	Uncharacterized protein; Belongs to the peptidase C14A family. (388 aa)
	casp8	Uncharacterized protein; Belongs to the peptidase C14A family. (526 aa)
	syk	Tyrosine-protein kinase. (619 aa)
	LOC101074739	Inositol 1,4,5-trisphosphate receptor, type 1a. (2743 aa)
	LOC101071755	Uncharacterized protein. (2728 aa)
	LOC101063692	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (736 aa)
	LOC101065438	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	bcl10	BCL10 immune signaling adaptor. (247 aa)
	LOC101076147	Uncharacterized protein. (193 aa)
	relb	V-rel avian reticuloendotheliosis viral oncogene homolog B. (591 aa)
	ksr1	Kinase suppressor of ras 1a. (987 aa)
	LOC101061527	Uncharacterized protein. (465 aa)
	LOC101071500	Uncharacterized protein. (257 aa)
	LOC101071292	Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (178 aa)
	LOC101071462	Signal transducer and activator of transcription. (794 aa)
	LOC101068369	Mitogen-activated protein kinase kinase kinase 14a. (887 aa)
	arhgef12	Rho guanine nucleotide exchange factor (GEF) 12a. (1437 aa)
	il17d	Interleukin-17D. (200 aa)
	il1b	Interleukin-1; Belongs to the IL-1 family. (256 aa)
	LOC101067377	Mitogen-activated protein kinase. (408 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (736 aa)
	calml4	Calmodulin-like 4a. (153 aa)
	NFATC1	Nuclear factor of activated T cells 1. (928 aa)
	LOC101068861	RHD domain-containing protein. (875 aa)
	src	Tyrosine-protein kinase. (552 aa)
	LOC101077059	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
	il12a	Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (234 aa)
	LOC101068711	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
	LOC101070117	Ras homolog gene family, member Aa. (193 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (390 aa)
	LOC101078121	C-type lectin domain-containing protein. (194 aa)
	LOC105417929	SCY domain-containing protein. (126 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	ENSTRUP00000052460	Ins145_P3_rec domain-containing protein. (206 aa)
	LOC101078865	Cylindromatosis (turban tumor syndrome), b. (689 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (210 aa)
	c-JunL	C-JunL protein; Belongs to the bZIP family. (293 aa)
	calm2	Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1040 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (383 aa)
	ENSTRUP00000056046	Nuclear factor of activated T cells 1. (813 aa)
	LOC101066563	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
	LOC101070452	Serine/threonine-protein phosphatase. (531 aa)
	LOC101073575	Mitogen-activated protein kinase. (427 aa)
	LOC101073266	Uncharacterized protein. (485 aa)
	H2RYE3_TAKRU	EF-hand domain-containing protein. (176 aa)
	nfkb1	Nuclear factor NF-kappa-B p105 subunit. (1506 aa)
	LOC101070190	Mitogen-activated protein kinase. (462 aa)
	LOC101064166	Uncharacterized protein. (193 aa)
	LOC101076232	Uncharacterized protein. (228 aa)
	LOC101079646	Signal transducer and activator of transcription. (761 aa)
	nfatc4	Uncharacterized protein. (893 aa)
	bcl3	ANK_REP_REGION domain-containing protein. (257 aa)
	pik3r3	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (497 aa)
	LOC101072650	Serine/threonine-protein phosphatase. (520 aa)
	lsp1	Lymphocyte-specific protein 1. (449 aa)
	LOC101067596	Mitogen-activated protein kinase kinase kinase 14. (933 aa)
	LOC101074783	Serine/threonine-protein phosphatase. (532 aa)
	nfatc3	Nuclear factor of activated T cells 3a. (1109 aa)
	LOC101062512	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (790 aa)
	LOC101069090	MALT paracaspase 2. (816 aa)
	LOC101073743	V-rel avian reticuloendotheliosis viral oncogene homolog A. (626 aa)
	ikbke	Protein kinase domain-containing protein. (721 aa)
	malt1	MALT paracaspase 1. (836 aa)
	LOC101078548	Mitogen-activated protein kinase. (456 aa)
	LOC101064045	Mitogen-activated protein kinase. (383 aa)
	LOC101068225	Component of inhibitor of nuclear factor kappa B kinase complex. (741 aa)
	rras2	RAS related 2. (202 aa)
	LOC101073734	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	ENSTRUP00000081534	Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1. (505 aa)
	LOC101076633	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (633 aa)
	LOC101074428	Mitogen-activated protein kinase. (412 aa)
	LOC101062695	Mitogen-activated protein kinase 12a. (361 aa)
	LOC101074026	Mitogen-activated protein kinase. (364 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (980 aa)
	ENSTRUP00000084409	NACHT, LRR and PYD domains-containing protein 3-like. (713 aa)
	LOC101065281	Tyrosine-protein kinase. (552 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
	mapk10	Mitogen-activated protein kinase. (537 aa)
	LOC101071975	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	CHUK	ENSTRUP00000021654	ENSTRUP00000073782	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.956
AKT2	ENSTRUP00000081534	ENSTRUP00000021654	ENSTRUP00000081534	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1.	0.814
AKT2	LOC101061527	ENSTRUP00000021654	ENSTRUP00000030225	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.814
AKT2	LOC101062512	ENSTRUP00000021654	ENSTRUP00000072960	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.814
AKT2	LOC101063692	ENSTRUP00000021654	ENSTRUP00000026411	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.814
AKT2	LOC101065281	ENSTRUP00000021654	ENSTRUP00000084615	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.433
AKT2	LOC101066563	ENSTRUP00000021654	ENSTRUP00000057781	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.926
AKT2	LOC101067191	ENSTRUP00000021654	ENSTRUP00000016050	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.823
AKT2	LOC101068225	ENSTRUP00000021654	ENSTRUP00000079843	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.961
AKT2	PIK3CA	ENSTRUP00000021654	ENSTRUP00000009530	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.823
AKT2	ikbkb	ENSTRUP00000021654	ENSTRUP00000041917	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.961
AKT2	ikbke	ENSTRUP00000021654	ENSTRUP00000077589	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.520
AKT2	mapk1	ENSTRUP00000021654	ENSTRUP00000051554	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.926
AKT2	mdm2	ENSTRUP00000021654	ENSTRUP00000020876	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MDM2 proto-oncogene.	0.973
AKT2	pik3cb	ENSTRUP00000021654	ENSTRUP00000017655	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.823
AKT2	pik3cd	ENSTRUP00000021654	ENSTRUP00000054260	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.823
AKT2	pik3r3	ENSTRUP00000021654	ENSTRUP00000066604	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.814
AKT2	src	ENSTRUP00000021654	ENSTRUP00000047001	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.431
CHUK	AKT2	ENSTRUP00000073782	ENSTRUP00000021654	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.956
CHUK	ENSTRUP00000000520	ENSTRUP00000073782	ENSTRUP00000000520	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	0.548