STRINGSTRING
HSD11B1 HSD11B1 DHCR24 DHCR24 LOC103000297 LOC103000297 LRRC72 LRRC72 FAXDC2 FAXDC2 NIPAL4 NIPAL4 ALDH1A2 ALDH1A2 LOC102998369 LOC102998369 KRBA2 KRBA2 LOC103011863 LOC103011863 LOC103009357 LOC103009357 PTGS2 PTGS2 LOC103006319 LOC103006319 LOC103002145 LOC103002145 LOC103003050 LOC103003050 PTGIR PTGIR LOC103001239 LOC103001239 SULT2B1 SULT2B1 SRD5A3 SRD5A3 LOC102998844 LOC102998844 LOC103000587 LOC103000587 LOC103014598 LOC103014598 RDH8 RDH8 LOC103015346 LOC103015346 DHRS3 DHRS3 LOC103012080 LOC103012080 LOC103011787 LOC103011787 DHCR7 DHCR7 CRABP2 CRABP2 PGRMC2 PGRMC2 PDXK PDXK CRABP1 CRABP1 LOC103020472 LOC103020472 RARB RARB PNPLA4 PNPLA4 STS STS TM7SF2 TM7SF2 CCDC160 CCDC160 LOC103007249 LOC103007249 RETSAT RETSAT LOC102997198 LOC102997198 HMGCR HMGCR LRAT LRAT SIGMAR1 SIGMAR1 MSMO1 MSMO1 HSD17B3 HSD17B3 TBXAS1 TBXAS1 AKR1D1 AKR1D1 LOC103017434 LOC103017434 LOC103019221 LOC103019221 PTGS1 PTGS1 PMVK PMVK LOC103014370 LOC103014370 LIPA LIPA ALDH1A3 ALDH1A3 CH25H CH25H VDR VDR SOAT2 SOAT2 PTGES3 PTGES3 LOC103009423 LOC103009423 LOC103001013 LOC103001013 RDH5 RDH5 LOC103008169 LOC103008169 MVK MVK EBP EBP LOC103020890 LOC103020890 LOC103017836 LOC103017836 ZNF280C ZNF280C ZNF169 ZNF169 ALDH1A1 ALDH1A1 SDR42E1 SDR42E1 BCO1 BCO1 HSD17B2 HSD17B2 LOC103009603 LOC103009603 LOC103017184 LOC103017184 RPE65 RPE65 PHOSPHO2 PHOSPHO2 NSDHL NSDHL RDH14 RDH14 PNPO PNPO CBR3 CBR3 LOC103007396 LOC103007396 HPGDS HPGDS RDH11 RDH11 RDH12 RDH12 ERG28 ERG28 LOC103011957 LOC103011957 AWAT2 AWAT2 RDH10 RDH10 LOC103015403 LOC103015403 PTGIS PTGIS LOC103015680 LOC103015680 HSD3B7 HSD3B7 LOC103014682 LOC103014682 LOC103007900 LOC103007900 LOC103017669 LOC103017669 LOC103018236 LOC103018236 RBP4 RBP4 LOC103016462 LOC103016462 LOC103016735 LOC103016735 LOC102999025 LOC102999025 SOAT1 SOAT1 SQLE SQLE LOC103007607 LOC103007607 LOC103000968 LOC103000968 AOX1 AOX1 HSD17B7 HSD17B7 LOC103005044 LOC103005044 SRD5A1 SRD5A1 FDFT1 FDFT1 LOC103000983 LOC103000983 SULT1E1 SULT1E1 LOC103015178 LOC103015178 DHRS12 DHRS12 LOC103008900 LOC103008900 RLBP1 RLBP1 PTGES PTGES PTGDS PTGDS SLC27A4 SLC27A4 PTGES2 PTGES2 CLCN2 CLCN2 SLC27A1 SLC27A1 LOC103016503 LOC103016503 LOC103007461 LOC103007461 HMGCS1 HMGCS1 SERINC4 SERINC4 SC5D SC5D LOC103007560 LOC103007560 STRA6 STRA6 LOC103011342 LOC103011342 LOC103008057 LOC103008057 PNPLA1 PNPLA1 HSD11B2 HSD11B2 LOC102998555 LOC102998555 LOC103009971 LOC103009971 LOC103003841 LOC103003841 LOC103011560 LOC103011560 TTR TTR LSS LSS DHRSX DHRSX TTC39B TTC39B SEMA6C SEMA6C SDR9C7 SDR9C7 LOC103016150 LOC103016150 LOC103009132 LOC103009132 LOC103016806 LOC103016806 DHRS9 DHRS9 LOC103014952 LOC103014952 RBP1 RBP1 LOC103019435 LOC103019435 LOC103019987 LOC103019987 LOC102999115 LOC102999115 LOC102999399 LOC102999399
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
HSD11B1Corticosteroid 11-beta-dehydrogenase isozyme 1. (294 aa)
DHCR24Delta(24)-sterol reductase. (516 aa)
LOC103000297Taurochenodeoxycholic 6 alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
LRRC72Leucine-rich repeat-containing protein 72. (288 aa)
FAXDC2Fatty acid hydroxylase domain-containing protein 2 isoform X1; Belongs to the sterol desaturase family. (343 aa)
NIPAL4Magnesium transporter NIPA4. (388 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
LOC102998369LOW QUALITY PROTEIN: hydroperoxide isomerase ALOXE3. (711 aa)
KRBA2KRAB-A domain-containing protein 2. (522 aa)
LOC103011863Cytochrome P450 2G1; Belongs to the cytochrome P450 family. (494 aa)
LOC103009357Cytochrome P450 11B1, mitochondrial; Belongs to the cytochrome P450 family. (412 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
LOC103006319Cytochrome P450 1A2-like; Belongs to the cytochrome P450 family. (159 aa)
LOC103002145Dihydrodiol dehydrogenase 3 isoform X1. (323 aa)
LOC103003050Aldo-keto reductase family 1 member C3 homolog isoform X1. (324 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LOC103001239Retinol dehydrogenase 16-like. (233 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (338 aa)
SRD5A3Polyprenol reductase. (289 aa)
LOC102998844Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
LOC103000587Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
LOC10301459825-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (468 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
LOC1030153463 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (373 aa)
DHRS3Short-chain dehydrogenase/reductase 3 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
LOC103012080Aromatase; Belongs to the cytochrome P450 family. (503 aa)
LOC103011787Aromatase-like; Belongs to the cytochrome P450 family. (503 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
PGRMC2Membrane-associated progesterone receptor component 2; Belongs to the cytochrome b5 family. (145 aa)
PDXKPyridoxal kinase. (422 aa)
CRABP1Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
LOC103020472Cytochrome P450 4F22; Belongs to the cytochrome P450 family. (531 aa)
RARBRetinoic acid receptor beta. (584 aa)
PNPLA4Patatin-like phospholipase domain-containing protein 4 isoform X1. (289 aa)
STSSteryl-sulfatase isoform X1. (578 aa)
TM7SF2Delta(14)-sterol reductase. (399 aa)
CCDC160Coiled-coil domain-containing protein 160. (325 aa)
LOC103007249Vitamin D 25-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
RETSATAll-trans-retinol 13,14-reductase isoform X1. (609 aa)
LOC102997198Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
LRATLecithin retinol acyltransferase isoform X1. (230 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
MSMO1Methylsterol monooxygenase 1 isoform X1; Belongs to the sterol desaturase family. (293 aa)
HSD17B3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
TBXAS1thromboxane-A synthase; Belongs to the cytochrome P450 family. (533 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase isoform X1. (326 aa)
LOC103017434Estradiol 17-beta-dehydrogenase 1-like isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (337 aa)
LOC103019221Estradiol 17-beta-dehydrogenase 1-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (622 aa)
PMVKPhosphomevalonate kinase. (192 aa)
LOC103014370Cholesterol 24-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
LIPALysosomal acid lipase/cholesteryl ester hydrolase isoform X1. (482 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa)
VDRVitamin D3 receptor. (427 aa)
SOAT2O-acyltransferase. (535 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
LOC103009423Retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC10300101325-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (508 aa)
RDH511-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)
LOC10300816917-beta-hydroxysteroid dehydrogenase type 6 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
EBPLOW QUALITY PROTEIN: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase. (233 aa)
LOC1030208903-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (194 aa)
LOC103017836Dehydrogenase/reductase SDR family member 4 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
ZNF280CLOW QUALITY PROTEIN: zinc finger protein 280C. (854 aa)
ZNF169Zinc finger protein 169. (599 aa)
ALDH1A1Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (476 aa)
SDR42E1Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa)
BCO1Beta,beta-carotene 15,15'-dioxygenase. (547 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa)
LOC103009603Magnesium transporter NIPA2. (360 aa)
LOC103017184Cytochrome P450 27C1; Belongs to the cytochrome P450 family. (466 aa)
RPE65Retinoid isomerohydrolase. (533 aa)
PHOSPHO2Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (361 aa)
RDH14Retinol dehydrogenase 14 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
PNPOPyridoxine-5'-phosphate oxidase isoform X1. (261 aa)
CBR3Carbonyl reductase [NADPH] 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
LOC103007396Carbonyl reductase [NADPH] 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
HPGDSHematopoietic prostaglandin D synthase. (200 aa)
RDH11Retinol dehydrogenase 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
ERG28Probable ergosterol biosynthetic protein 28. (140 aa)
LOC103011957UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
AWAT2acyl-CoA wax alcohol acyltransferase 2. (333 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
LOC1030154031,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
PTGISProstacyclin synthase. (516 aa)
LOC103015680LOW QUALITY PROTEIN: carbonyl reductase [NADPH] 2-like. (244 aa)
HSD3B73 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa)
LOC103014682Cytochrome P450 3A29-like. (503 aa)
LOC103007900Steroid 17-alpha-hydroxylase/17,20 lyase isoform X1; Belongs to the cytochrome P450 family. (509 aa)
LOC103017669Cytochrome P450 2C23-like; Belongs to the cytochrome P450 family. (504 aa)
LOC103018236Cytochrome P450 2C18-like. (254 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (196 aa)
LOC103016462Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (461 aa)
LOC103016735Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (523 aa)
LOC102999025Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (537 aa)
SOAT1O-acyltransferase. (550 aa)
SQLESqualene monooxygenase. (574 aa)
LOC103007607Cytochrome P450 2D14 isoform X1; Belongs to the cytochrome P450 family. (499 aa)
LOC1030009683-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (498 aa)
AOX1LOW QUALITY PROTEIN: aldehyde oxidase. (1338 aa)
HSD17B73-keto-steroid reductase isoform X1. (334 aa)
LOC1030050443-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (254 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
FDFT1Squalene synthase isoform X1. (417 aa)
LOC1030009835-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
SULT1E1Sulfotransferase; Belongs to the sulfotransferase 1 family. (300 aa)
LOC10301517824-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (469 aa)
DHRS12Dehydrogenase/reductase SDR family member 12 isoform X1. (317 aa)
LOC103008900UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
RLBP1Retinaldehyde-binding protein 1. (317 aa)
PTGESProstaglandin E synthase. (153 aa)
PTGDSprostaglandin-H2 D-isomerase isoform X1; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
SLC27A4Long-chain fatty acid transport protein 4. (643 aa)
PTGES2Prostaglandin E synthase 2 isoform X1. (394 aa)
CLCN2Chloride channel protein 2 isoform X1. (891 aa)
SLC27A1Long-chain fatty acid transport protein 1 isoform X1. (646 aa)
LOC103016503Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa)
LOC103007461Cytochrome P450 2J6-like; Belongs to the cytochrome P450 family. (468 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
SERINC4LOW QUALITY PROTEIN: serine incorporator 4. (519 aa)
SC5DLathosterol oxidase; Belongs to the sterol desaturase family. (299 aa)
LOC103007560Cytochrome P450 1A2 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
STRA6Receptor for retinol uptake STRA6 isoform X1. (685 aa)
LOC103011342Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC103008057Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
PNPLA1Patatin-like phospholipase domain-containing protein 1. (519 aa)
HSD11B2Corticosteroid 11-beta-dehydrogenase isozyme 2. (509 aa)
LOC102998555LOW QUALITY PROTEIN: cytochrome P450 2A13-like. (479 aa)
LOC103009971UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
LOC103003841Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (529 aa)
LOC103011560LOW QUALITY PROTEIN: cytochrome P450 2S1-like; Belongs to the cytochrome P450 family. (494 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (146 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (655 aa)
DHRSXDehydrogenase/reductase SDR family member on chromosome X. (268 aa)
TTC39BTetratricopeptide repeat protein 39B isoform X1. (645 aa)
SEMA6Csemaphorin-6C; Belongs to the semaphorin family. (876 aa)
SDR9C7Short-chain dehydrogenase/reductase family 9C member 7 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa)
LOC103016150Retinol dehydrogenase 16-like. (182 aa)
LOC103009132LOW QUALITY PROTEIN: retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC103016806LOW QUALITY PROTEIN: retinoic acid receptor beta-like. (358 aa)
DHRS9Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
LOC103014952Cytochrome P450 3A24. (503 aa)
RBP1Retinol-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
LOC103019435LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (375 aa)
LOC103019987LOW QUALITY PROTEIN: phylloquinone omega-hydroxylase CYP4F2-like. (327 aa)
LOC102999115LOW QUALITY PROTEIN: cytochrome P450 2F3. (433 aa)
LOC102999399LOW QUALITY PROTEIN: cytochrome P450 2F2-like. (558 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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