STRINGSTRING
NADK NADK CD38 CD38 BST1 BST1 NMRK2 NMRK2 SIRT6 SIRT6 NMNAT1 NMNAT1 SIRT3 SIRT3 NADSYN1 NADSYN1 LOC103010251 LOC103010251 LOC103000152 LOC103000152 SIRT5 SIRT5 NMNAT2 NMNAT2 SIRT2 SIRT2 NAMPT NAMPT NMRK1 NMRK1 SIRT4 SIRT4 SIRT7 SIRT7 QPRT QPRT NMNAT3 NMNAT3 NUDT12 NUDT12 NADK2 NADK2 NNT NNT NT5E NT5E
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NADKNAD kinase isoform X3. (453 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (291 aa)
BST1ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (357 aa)
NMRK2Nicotinamide riboside kinase 2 isoform X1. (227 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (281 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (260 aa)
NADSYN1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa)
LOC103010251Nicotinamide N-methyltransferase. (264 aa)
LOC103000152NAD(P)(+)--arginine ADP-ribosyltransferase. (292 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (358 aa)
NMNAT2Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2. (307 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (520 aa)
NMRK1Nicotinamide riboside kinase 1 isoform X1. (199 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7. (345 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (322 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (239 aa)
NUDT12Peroxisomal NADH pyrophosphatase NUDT12. (461 aa)
NADK2NAD kinase 2, mitochondrial isoform X1. (301 aa)
NNTNAD(P) transhydrogenase, mitochondrial. (1086 aa)
NT5E5'-nucleotidase isoform X1; Belongs to the 5'-nucleotidase family. (470 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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