STRINGSTRING
LRWD1 LRWD1 RING1 RING1 BAZ1B BAZ1B HELLS HELLS SMARCA5 SMARCA5 BMI1 BMI1 SUZ12 SUZ12 ORC2 ORC2 BEND3 BEND3 DNMT3A DNMT3A TASOR TASOR ESCO2 ESCO2 CENPC CENPC CENPB CENPB PHC1 PHC1 TNKS1BP1 TNKS1BP1 PML PML MBD3L1 MBD3L1 WDR76 WDR76 DNMT1 DNMT1 MORC2 MORC2 LOC103014251 LOC103014251 PSIP1 PSIP1 ZNF618 ZNF618 LOC103003208 LOC103003208 LOC103006490 LOC103006490 LOC103010526 LOC103010526 CBX6 CBX6 MBD2 MBD2 SIRT6 SIRT6 PCGF2 PCGF2 IKZF1 IKZF1 CBX5 CBX5 HMGA2 HMGA2 BAZ2A BAZ2A SUV39H1 SUV39H1 BAZ1A BAZ1A KMT5C KMT5C ZBTB18 ZBTB18 PHC2 PHC2 NCAPD3 NCAPD3 UBA1 UBA1 CBX1 CBX1 SMARCAD1 SMARCAD1 ATRX ATRX EZH2 EZH2 SNAI1 SNAI1 SALL4 SALL4 MECP2 MECP2 CBX8 CBX8 CBX2 CBX2 TCP1 TCP1 RRP8 RRP8 DNMT3L DNMT3L TOP2B TOP2B INCENP INCENP TRIM28 TRIM28 EME1 EME1 MBD3 MBD3 KDM4A KDM4A RNF2 RNF2 CHRAC1 CHRAC1 SALL1 SALL1 SIRT1 SIRT1 NOP53 NOP53 LOC102997638 LOC102997638 KDM4B KDM4B UHRF1 UHRF1 HDAC1 HDAC1 CBX3 CBX3 LOC103002265 LOC103002265
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRWD1Leucine-rich repeat and WD repeat-containing protein 1. (651 aa)
RING1E3 ubiquitin-protein ligase RING1. (406 aa)
BAZ1BTyrosine-protein kinase BAZ1B. (1452 aa)
HELLSLOW QUALITY PROTEIN: lymphoid-specific helicase. (875 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
SUZ12Polycomb protein SUZ12. (694 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
BEND3BEN domain-containing protein 3. (828 aa)
DNMT3ADNA (Cytosine-5)-methyltransferase 3A; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (910 aa)
TASORProtein TASOR isoform X1. (1672 aa)
ESCO2N-acetyltransferase ESCO2. (612 aa)
CENPCCentromere protein C. (943 aa)
CENPBMajor centromere autoantigen B. (460 aa)
PHC1Polyhomeotic-like protein 1. (997 aa)
TNKS1BP1182 kDa tankyrase-1-binding protein. (1721 aa)
PMLProtein PML isoform X1. (871 aa)
MBD3L1LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 3-like 1. (192 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (632 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1348 aa)
MORC2MORC family CW-type zinc finger protein 2. (1015 aa)
LOC103014251LOW QUALITY PROTEIN: inner centromere protein-like. (810 aa)
PSIP1PC4 and SFRS1-interacting protein isoform X1. (530 aa)
ZNF618Zinc finger protein 618 isoform X1. (900 aa)
LOC103003208LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RING1-like. (406 aa)
LOC103006490LOW QUALITY PROTEIN: sal-like protein 4. (901 aa)
LOC103010526LOW QUALITY PROTEIN: ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1074 aa)
CBX6Chromobox protein homolog 6 isoform X1. (415 aa)
MBD2methyl-CpG-binding domain protein 2. (262 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (345 aa)
IKZF1DNA-binding protein Ikaros. (507 aa)
CBX5Chromobox protein homolog 5. (191 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
BAZ2ABromodomain adjacent to zinc finger domain protein 2A isoform X1. (1911 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
BAZ1ABromodomain adjacent to zinc finger domain protein 1A isoform X1. (1557 aa)
KMT5CHistone-lysine N-methyltransferase KMT5C. (351 aa)
ZBTB18Zinc finger and BTB domain-containing protein 18 isoform X1. (535 aa)
PHC2LOW QUALITY PROTEIN: polyhomeotic-like protein 2. (851 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1514 aa)
UBA1Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
CBX1Chromobox protein homolog 1. (185 aa)
SMARCAD1annotation not available (1028 aa)
ATRXLOW QUALITY PROTEIN: transcriptional regulator ATRX. (2488 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (746 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
SALL4Sal-like protein 4. (1068 aa)
MECP2methyl-CpG-binding protein 2. (459 aa)
CBX8Chromobox protein homolog 8. (371 aa)
CBX2Chromobox protein homolog 2. (494 aa)
TCP1T-complex protein 1 subunit alpha isoform X1. (556 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (458 aa)
DNMT3LDNA (Cytosine-5)-methyltransferase 3-like. (417 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1541 aa)
INCENPInner centromere protein. (889 aa)
TRIM28Transcription intermediary factor 1-beta. (700 aa)
EME1Crossover junction endonuclease EME1 isoform X1. (581 aa)
MBD3methyl-CpG-binding domain protein 3. (233 aa)
KDM4ALysine-specific demethylase 4A isoform X1. (1072 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (344 aa)
CHRAC1Chromatin accessibility complex protein 1. (132 aa)
SALL1Sal-like protein 1. (1217 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (472 aa)
LOC102997638DNA (Cytosine-5)-methyltransferase 1-like. (185 aa)
KDM4BLysine-specific demethylase 4B isoform X1. (1121 aa)
UHRF1E3 ubiquitin-protein ligase UHRF1. (750 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
CBX3Chromobox protein homolog 3. (183 aa)
LOC103002265Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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