STRINGSTRING
SNAI1 SNAI1 MAP2K6 MAP2K6 AXIN2 AXIN2 SIRT7 SIRT7 ACHE ACHE IGFBP3 IGFBP3 GLI3 GLI3 IHH IHH WWTR1 WWTR1 LOX LOX CCN4 CCN4 MAPK11 MAPK11 SMAD1 SMAD1 UCMA UCMA LOC103001880 LOC103001880 BMPR2 BMPR2 LOC103020748 LOC103020748 ASF1A ASF1A BMP2 BMP2 LOC103016570 LOC103016570 HAND2 HAND2 MEF2C MEF2C BMP4 BMP4 CTNNB1 CTNNB1 FGF9 FGF9 GLIS1 GLIS1 DLX5 DLX5 TWIST1 TWIST1 MYOC MYOC TNN TNN BMP3 BMP3 SMAD3 SMAD3 LOC103000311 LOC103000311 SNAI2 SNAI2 LIMD1 LIMD1 PTH1R PTH1R WNT3A WNT3A MEF2D MEF2D BGLAP BGLAP JUNB JUNB SMAD5 SMAD5 FHL2 FHL2 CCN1 CCN1 CTHRC1 CTHRC1 BMP6 BMP6 MEN1 MEN1 BMPR1A BMPR1A EPHA2 EPHA2 LOC103011144 LOC103011144 WNT3 WNT3 FIGNL1 FIGNL1 ADAR ADAR GDF10 GDF10 GDF2 GDF2 WNT10B WNT10B SP7 SP7 GLI1 GLI1 DHH DHH TMEM119 TMEM119 LGR4 LGR4 SOX8 SOX8 SFRP1 SFRP1 WWOX WWOX LOC103004151 LOC103004151 BMPR1B BMPR1B HDAC4 HDAC4 LOC103015403 LOC103015403 TP53INP2 TP53INP2 WNT11 WNT11 RUNX2 RUNX2 LOC103013794 LOC103013794 LOC103010562 LOC103010562 JUND JUND FZD1 FZD1 LOC103016126 LOC103016126 LOC103014627 LOC103014627 CBFB CBFB LRP5 LRP5 LRP5L LRP5L HOXA2 HOXA2 FGF2 FGF2 SHOX2 SHOX2 NOG NOG COL1A1 COL1A1 SMO SMO SHH SHH LOC114238459 LOC114238459 IFT80 IFT80 NF1 NF1 SATB2 SATB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNAI1Zinc finger protein SNAI1. (264 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (368 aa)
AXIN2Axin-2. (543 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7. (345 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (615 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (146 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
IHHIndian hedgehog protein. (309 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
LOXProtein-lysine 6-oxidase. (284 aa)
CCN4WNT1-inducible-signaling pathway protein 1. (323 aa)
MAPK11Mitogen-activated protein kinase. (281 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
UCMAUnique cartilage matrix-associated protein isoform X1. (138 aa)
LOC103001880C-C motif chemokine. (93 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LOC103020748Histone chaperone ASF1A-like. (197 aa)
ASF1AHistone chaperone ASF1A. (153 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
LOC103016570Peroxisomal multifunctional enzyme type 2-like. (121 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (130 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
CTNNB1Catenin beta-1. (767 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GLIS1Zinc finger protein GLIS1. (818 aa)
DLX5Homeobox protein DLX-5. (289 aa)
TWIST1Twist-related protein 1. (153 aa)
MYOCMyocilin. (473 aa)
TNNtenascin-N. (1266 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC103000311Histone H3; Belongs to the histone H3 family. (136 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
LIMD1LIM domain-containing protein 1. (188 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (530 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MEF2DLOW QUALITY PROTEIN: myocyte-specific enhancer factor 2D. (512 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
JUNBTranscription factor jun-B. (254 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
FHL2Four and a half LIM domains protein 2. (279 aa)
CCN1Protein CYR61. (382 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
BMP6Bone morphogenetic protein 6. (388 aa)
MEN1Menin. (517 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
LOC103011144Histone H3.3-like. (136 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa)
ADARDouble-stranded RNA-specific adenosine deaminase isoform X1. (1176 aa)
GDF10Growth/differentiation factor 10. (544 aa)
GDF2Growth/differentiation factor 2. (432 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SP7Transcription factor Sp7. (431 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
TMEM119Transmembrane protein 119. (304 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (921 aa)
SOX8LOW QUALITY PROTEIN: transcription factor SOX-8. (474 aa)
SFRP1Secreted frizzled-related protein 1. (295 aa)
WWOXWW domain-containing oxidoreductase. (414 aa)
LOC103004151LIM domain-containing protein 1-like. (279 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1149 aa)
LOC1030154031,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
TP53INP2Tumor protein p53-inducible nuclear protein 2 isoform X1. (220 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
RUNX2Runt-related transcription factor 2. (343 aa)
LOC103013794Peroxisomal multifunctional enzyme type 2-like. (190 aa)
LOC103010562Histone H3; Belongs to the histone H3 family. (136 aa)
JUNDTranscription factor jun-D. (262 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC103016126Peroxisomal multifunctional enzyme type 2-like. (145 aa)
LOC103014627Uncharacterized protein LOC103014627 isoform X1. (142 aa)
CBFBCore-binding factor subunit beta. (151 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1080 aa)
LRP5LLOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein. (469 aa)
HOXA2LOW QUALITY PROTEIN: homeobox protein Hox-A2. (369 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (332 aa)
NOGNoggin. (154 aa)
COL1A1LOW QUALITY PROTEIN: collagen alpha-1(I) chain. (1462 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
LOC114238459Histone H3.3-like. (127 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (808 aa)
NF1Neurofibromin. (2821 aa)
SATB2DNA-binding protein SATB. (853 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.