71 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IHH	Indian hedgehog protein. (309 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1591 aa)
	DMRTA2	Doublesex- and mab-3-related transcription factor A2. (390 aa)
	ASCL1	Achaete-scute homolog 1. (169 aa)
	KDM6B	LOW QUALITY PROTEIN: lysine-specific demethylase 6B. (1504 aa)
	GSX2	GS homeobox 2. (299 aa)
	SOX17	Transcription factor SOX-17. (296 aa)
	TBX15	T-box transcription factor TBX15 isoform X1. (602 aa)
	POU3F2	POU domain protein. (263 aa)
	TEAD4	Transcriptional enhancer factor TEF-3. (580 aa)
	TBX5	T-box transcription factor TBX5 isoform X1. (536 aa)
	TBX10	T-box transcription factor TBX10. (389 aa)
	TLX3	T-cell leukemia homeobox protein 3. (291 aa)
	HOXA11	Homeobox protein Hox-A11. (314 aa)
	HOXA13	Homeobox protein Hox-A13. (294 aa)
	TBX19	T-box transcription factor TBX19. (444 aa)
	ISL2	Insulin gene enhancer protein ISL-2. (359 aa)
	DBX1	Homeobox protein DBX1. (349 aa)
	TBX21	T-box transcription factor TBX21. (379 aa)
	FOXA1	Hepatocyte nuclear factor 3-alpha. (433 aa)
	HOXC10	Homeobox protein Hox-C10 isoform X1. (368 aa)
	DHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
	TBX3	T-box transcription factor TBX3. (670 aa)
	MGA	MAX gene-associated protein isoform X1. (3115 aa)
	PAX6	Paired box protein Pax-6 isoform X1. (493 aa)
	DMRT3	Doublesex- and mab-3-related transcription factor 3. (506 aa)
	TBX20	T-box transcription factor TBX20. (449 aa)
	TBR1	T-box brain protein 1. (798 aa)
	CDON	Cell adhesion molecule-related/down-regulated by oncogenes. (1251 aa)
	OLIG2	Oligodendrocyte transcription factor 2. (254 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (469 aa)
	PRDM14	PR domain zinc finger protein 14. (571 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (584 aa)
	SOX9	Transcription factor SOX-9. (432 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
	POU4F1	POU domain protein. (298 aa)
	TBX6	T-box transcription factor TBX6. (436 aa)
	MYL10	Myosin regulatory light chain 10. (167 aa)
	SUFU	Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
	TENM4	Teneurin-4. (2739 aa)
	TBX22	T-box transcription factor TBX22. (522 aa)
	PTCH2	Protein patched homolog 2 isoform X1. (1213 aa)
	TBXT	T-box transcription factor T isoform X2. (436 aa)
	KDM6A	Lysine-specific demethylase 6A. (1180 aa)
	SHH	LOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
	ETV2	ETS translocation variant 2 isoform X1. (333 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
	PTCH1	LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
	NODAL	Nodal homolog. (280 aa)
	NOTCH1	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
	TBX2	LOW QUALITY PROTEIN: T-box transcription factor TBX2. (592 aa)
	ATOH1	LOW QUALITY PROTEIN: protein atonal homolog 1. (348 aa)
	APC2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (1582 aa)
	TBX18	T-box transcription factor TBX18. (607 aa)
	MYT1L	Myelin transcription factor 1-like protein. (912 aa)
	ISL1	Insulin gene enhancer protein ISL-1. (349 aa)
	LHX3	LIM/homeobox protein Lhx3. (493 aa)
	EHMT2	Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
	CTNNB1	Catenin beta-1. (767 aa)
	SIX1	Homeobox protein SIX1. (284 aa)
	APC	Adenomatous polyposis coli protein isoform X1. (2865 aa)
	NKX2-2	Homeobox protein Nkx-2.2. (273 aa)
	EOMES	Eomesodermin homolog isoform X1. (419 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (281 aa)
	HOXD10	Homeobox protein Hox-D10. (343 aa)
	TBX4	T-box transcription factor TBX4. (557 aa)
	SIX2	Homeobox protein SIX2 isoform X1. (298 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	MYL2	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	FEV	Protein FEV. (184 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	APC2	A0A384AXK8	A0A384BFV4	Adenomatous polyposis coli protein isoform X1.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.902
APC	CTNNB1	A0A384AXK8	A0A384B1J6	Adenomatous polyposis coli protein isoform X1.	Catenin beta-1.	0.999
APC2	APC	A0A384BFV4	A0A384AXK8	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	Adenomatous polyposis coli protein isoform X1.	0.902
APC2	CTNNB1	A0A384BFV4	A0A384B1J6	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	Catenin beta-1.	0.988
ASCL1	ATOH1	A0A383YTI0	A0A384BGJ9	Achaete-scute homolog 1.	LOW QUALITY PROTEIN: protein atonal homolog 1.	0.497
ASCL1	DLL1	A0A383YTI0	A0A384AFJ6	Achaete-scute homolog 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.508
ASCL1	EOMES	A0A383YTI0	A0A384AWG4	Achaete-scute homolog 1.	Eomesodermin homolog isoform X1.	0.412
ASCL1	GSX2	A0A383YTI0	A0A383Z076	Achaete-scute homolog 1.	GS homeobox 2.	0.761
ASCL1	ISL1	A0A383YTI0	A0A384B7J6	Achaete-scute homolog 1.	Insulin gene enhancer protein ISL-1.	0.590
ASCL1	ISL2	A0A383YTI0	A0A383ZEI7	Achaete-scute homolog 1.	Insulin gene enhancer protein ISL-2.	0.471
ASCL1	LHX3	A0A383YTI0	A0A384B530	Achaete-scute homolog 1.	LIM/homeobox protein Lhx3.	0.451
ASCL1	MYT1L	A0A383YTI0	A0A384B7X9	Achaete-scute homolog 1.	Myelin transcription factor 1-like protein.	0.731
ASCL1	NKX2-2	A0A383YTI0	A0A384AXE8	Achaete-scute homolog 1.	Homeobox protein Nkx-2.2.	0.476
ASCL1	OLIG2	A0A383YTI0	A0A384A9I6	Achaete-scute homolog 1.	Oligodendrocyte transcription factor 2.	0.767
ASCL1	PAX6	A0A383YTI0	A0A384A1M2	Achaete-scute homolog 1.	Paired box protein Pax-6 isoform X1.	0.596
ASCL1	POU3F2	A0A383YTI0	A0A383Z4B8	Achaete-scute homolog 1.	POU domain protein.	0.511
ASCL1	SHH	A0A383YTI0	A0A452CFB9	Achaete-scute homolog 1.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.527
ASCL1	SOX9	A0A383YTI0	A0A384AFJ4	Achaete-scute homolog 1.	Transcription factor SOX-9.	0.593
ASCL1	TBR1	A0A383YTI0	A0A384A7Y6	Achaete-scute homolog 1.	T-box brain protein 1.	0.472
ASCL1	TLX3	A0A383YTI0	A0A383Z960	Achaete-scute homolog 1.	T-cell leukemia homeobox protein 3.	0.430