49 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (469 aa)
	PLXNA2	plexin-A2 isoform X2. (1894 aa)
	MEOX2	Homeobox protein MOX-2. (303 aa)
	XRCC2	DNA repair protein XRCC2. (280 aa)
	ALDH1A2	Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	FOXB1	Forkhead box protein B1. (325 aa)
	ABI1	Abl interactor 1 isoform X11. (508 aa)
	NKX3-1	Homeobox protein Nkx-3.1. (153 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	FOXF1	Forkhead box protein F1. (354 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
	TAF10	Transcription initiation factor TFIID subunit 10. (177 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	LFNG	Beta-1,3-N-acetylglucosaminyltransferase. (328 aa)
	LOC103006469	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
	TCAP	Telethonin. (167 aa)
	MEOX1	Homeobox protein MOX-1. (254 aa)
	EPB41L5	Band 4.1-like protein 5. (805 aa)
	POGLUT1	Protein O-glucosyltransferase 1 isoform X1. (392 aa)
	SFRP1	Secreted frizzled-related protein 1. (295 aa)
	NRARP	Notch-regulated ankyrin repeat-containing protein. (114 aa)
	MSGN1	Mesogenin-1. (193 aa)
	MED12	Mediator of RNA polymerase II transcription subunit 12. (2073 aa)
	AXIN2	Axin-2. (543 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
	TBX6	T-box transcription factor TBX6. (436 aa)
	LOC103004539	Protocadherin-8. (839 aa)
	LOC103004257	Protocadherin-8-like. (686 aa)
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	LHX1	LIM/homeobox protein Lhx1. (406 aa)
	NLE1	Notchless protein homolog 1 isoform X1. (444 aa)
	PAX1	Paired box protein Pax-1. (462 aa)
	LOC103001360	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
	POFUT1	GDP-fucose protein O-fucosyltransferase 1. (391 aa)
	LOC103015737	Mesoderm posterior protein 1. (126 aa)
	CRB2	Protein crumbs homolog 2. (1075 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	TBX18	T-box transcription factor TBX18. (607 aa)
	SMAD4	Mothers against decapentaplegic homolog. (553 aa)
	LRP6	Low-density lipoprotein receptor-related protein 6 isoform X1. (1463 aa)
	MIB1	E3 ubiquitin-protein ligase MIB1. (923 aa)
	KAT2A	LOW QUALITY PROTEIN: histone acetyltransferase KAT2A. (839 aa)
	LOC103012500	LOW QUALITY PROTEIN: histone acetyltransferase KAT2A-like. (732 aa)
	SEMA3C	semaphorin-3C; Belongs to the semaphorin family. (548 aa)
	DLL3	Delta-like protein 3. (587 aa)
	TBXT	T-box transcription factor T isoform X2. (436 aa)
	COBL	Protein cordon-bleu isoform X1. (1383 aa)
	EP300	Histone acetyltransferase p300. (2445 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	TBX18	A0A383YT04	A0A384B8E9	Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family.	T-box transcription factor TBX18.	0.438
ATM	EP300	A0A383ZCZ2	A0A452CM43	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Histone acetyltransferase p300.	0.485
ATM	XRCC2	A0A383ZCZ2	A0A383YRN1	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA repair protein XRCC2.	0.705
AXIN2	LOC103001360	A0A384AFA5	A0A384B074	Axin-2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.615
AXIN2	LOC103006469	A0A384AFA5	A0A383ZID1	Axin-2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.615
AXIN2	LRP6	A0A384AFA5	A0A452C5A4	Axin-2.	Low-density lipoprotein receptor-related protein 6 isoform X1.	0.873
AXIN2	SFRP1	A0A384AFA5	A0A384A4K5	Axin-2.	Secreted frizzled-related protein 1.	0.604
AXIN2	SFRP2	A0A384AFA5	A0A384AQ78	Axin-2.	Secreted frizzled-related protein 2.	0.548
AXIN2	WNT3A	A0A384AFA5	A0A383Z4E5	Axin-2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.659
BMPR1A	MEOX2	A0A383ZHP5	A0A383YQ29	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Homeobox protein MOX-2.	0.456
BMPR1A	SMAD3	A0A383ZHP5	A0A383YTC5	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.957
BMPR1A	SMAD4	A0A383ZHP5	A0A384BC65	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.820
CRB2	DLL3	A0A384B5K8	A0A452CFI6	Protein crumbs homolog 2.	Delta-like protein 3.	0.452
CRB2	NRARP	A0A384B5K8	A0A384A5Y8	Protein crumbs homolog 2.	Notch-regulated ankyrin repeat-containing protein.	0.429
CRB2	POGLUT1	A0A384B5K8	A0A384A3L9	Protein crumbs homolog 2.	Protein O-glucosyltransferase 1 isoform X1.	0.646
DLL1	LFNG	A0A384AFJ6	A0A383ZHT4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.552
DLL1	MIB1	A0A384AFJ6	A0A452C5Y0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	E3 ubiquitin-protein ligase MIB1.	0.428
DLL1	NRARP	A0A384AFJ6	A0A384A5Y8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch-regulated ankyrin repeat-containing protein.	0.488
DLL1	POFUT1	A0A384AFJ6	A0A384B129	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GDP-fucose protein O-fucosyltransferase 1.	0.537
DLL1	WNT3A	A0A384AFJ6	A0A383Z4E5	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.500