STRINGSTRING
ERCC2 ERCC2 NF1 NF1 LOC103005590 LOC103005590 LOC114238716 LOC114238716 LAMA5 LAMA5 EDA EDA DNASE1L2 DNASE1L2 SHH SHH SMO SMO SOX21 SOX21 DSG4 DSG4 LOC103015272 LOC103015272 TP63 TP63 NOTCH1 NOTCH1 LOC103016577 LOC103016577 LHX2 LHX2 FOXE1 FOXE1 APCDD1 APCDD1 FST FST FGF10 FGF10 LGR5 LGR5 CTNNB1 CTNNB1 TRPC4AP TRPC4AP FZD3 FZD3 SAV1 SAV1 BCL2 BCL2 NSUN2 NSUN2 EXT1 EXT1 LOC103017310 LOC103017310 WNT10A WNT10A INHBA INHBA LDB1 LDB1 SOX9 SOX9 SNAI1 SNAI1 FUZ FUZ FOXN1 FOXN1 NSDHL NSDHL PUM2 PUM2 LRP4 LRP4 ALX4 ALX4 LGR4 LGR4 ACVR1B ACVR1B LOC103017521 LOC103017521 ZDHHC21 ZDHHC21 DLX3 DLX3 NGFR NGFR TGFB2 TGFB2 FZD6 FZD6 GORAB GORAB INTU INTU TMEM79 TMEM79 RELA RELA HDAC1 HDAC1 FGF7 FGF7 PIAS4 PIAS4 LDB2 LDB2 SOS1 SOS1 CD109 CD109 NOM1 NOM1 SOSTDC1 SOSTDC1 ZMPSTE24 ZMPSTE24 TNFRSF19 TNFRSF19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD. (760 aa)
NF1Neurofibromin. (2821 aa)
LOC103005590Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2674 aa)
LOC114238716Cadherin EGF LAG seven-pass G-type receptor 1-like isoform X1. (79 aa)
LAMA5LOW QUALITY PROTEIN: laminin subunit alpha-5. (3531 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (308 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
SOX21Transcription factor SOX-21. (181 aa)
DSG4LOW QUALITY PROTEIN: desmoglein-4. (679 aa)
LOC103015272LOW QUALITY PROTEIN: LIM domain-binding protein 2-like. (246 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
LOC103016577Keratin, type I cytoskeletal 25-like; Belongs to the intermediate filament family. (215 aa)
LHX2LOW QUALITY PROTEIN: LIM/homeobox protein Lhx2. (406 aa)
FOXE1LOW QUALITY PROTEIN: forkhead box protein E1. (331 aa)
APCDD1Protein APCDD1. (527 aa)
FSTFollistatin isoform X1. (344 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1. (907 aa)
CTNNB1Catenin beta-1. (767 aa)
TRPC4APShort transient receptor potential channel 4-associated protein isoform X1. (797 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SAV1Protein salvador homolog 1. (351 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
NSUN2tRNA (Cytosine(34)-C(5))-methyltransferase isoform X2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (742 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LOC103017310Phospholipase A(2). (159 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
INHBAInhibin beta A chain. (425 aa)
LDB1LIM domain-binding protein 1 isoform X2. (375 aa)
SOX9Transcription factor SOX-9. (432 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
FUZProtein fuzzy homolog. (389 aa)
FOXN1Forkhead box protein N1. (645 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (361 aa)
PUM2Pumilio homolog 2 isoform X1. (1065 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1901 aa)
ALX4Homeobox protein aristaless-like 4. (406 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (921 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
LOC103017521Keratin, type I cytoskeletal 17 isoform X1; Belongs to the intermediate filament family. (463 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
DLX3Homeobox protein DLX-3. (287 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
GORABLOW QUALITY PROTEIN: RAB6-interacting golgin. (396 aa)
INTUProtein inturned. (935 aa)
TMEM79Transmembrane protein 79. (395 aa)
RELATranscription factor p65 isoform X1. (520 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (491 aa)
LDB2LIM domain-binding protein 2 isoform X1. (373 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1001 aa)
CD109CD109 antigen. (1312 aa)
NOM1Nucleolar MIF4G domain-containing protein 1. (722 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
TNFRSF19Tumor necrosis factor receptor superfamily member 19 isoform X1. (428 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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