46 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBX20	T-box transcription factor TBX20. (449 aa)
	ARL13B	ADP-ribosylation factor-like protein 13B isoform X1. (430 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	SOX17	Transcription factor SOX-17. (296 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	LOC103006469	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
	MICALCL	MICAL C-terminal-like protein. (710 aa)
	MICAL2	F-actin-monooxygenase MICAL2 isoform X1. (1114 aa)
	ZIC3	Zinc finger protein ZIC 3. (163 aa)
	TBX3	T-box transcription factor TBX3. (670 aa)
	CCDC103	Coiled-coil domain-containing protein 103. (235 aa)
	NPHP3	Nephrocystin-3 isoform X1. (1191 aa)
	PKD2	Polycystin-2. (763 aa)
	CLUAP1	Clusterin-associated protein 1 isoform X1. (457 aa)
	HAND1	Heart- and neural crest derivatives-expressed protein 1 isoform X1. (217 aa)
	SHH	LOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
	C2CD3	C2 domain-containing protein 3 isoform X1. (2349 aa)
	LOC114236675	LOW QUALITY PROTEIN: folate receptor alpha-like. (249 aa)
	NOTCH2	Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
	NODAL	Nodal homolog. (280 aa)
	SRF	Serum response factor. (464 aa)
	MIB1	E3 ubiquitin-protein ligase MIB1. (923 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	NOTCH1	LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
	CCDC39	Coiled-coil domain-containing protein 39. (941 aa)
	LOC103015737	Mesoderm posterior protein 1. (126 aa)
	ENG	Endoglin isoform X1. (652 aa)
	IFT52	Intraflagellar transport protein 52 homolog isoform X1. (461 aa)
	MEF2C	Myocyte-specific enhancer factor 2C isoform X5. (483 aa)
	LOC103001360	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
	HAND2	Heart- and neural crest derivatives-expressed protein 2. (130 aa)
	AHI1	Jouberin isoform X1. (1197 aa)
	IHH	Indian hedgehog protein. (309 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	LBX1	Transcription factor LBX1. (282 aa)
	SUFU	Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
	IFT57	Intraflagellar transport protein 57 homolog. (427 aa)
	TBX6	T-box transcription factor TBX6. (436 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
	CCDC40	Coiled-coil domain-containing protein 40. (1131 aa)
	FOXH1	Forkhead box protein H1. (360 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (469 aa)
	ASB2	Ankyrin repeat and SOCS box protein 2. (633 aa)
	DNAAF1	Dynein assembly factor 1, axonemal. (648 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	ARL13B	A0A384AUJ6	A0A383YMX6	Jouberin isoform X1.	ADP-ribosylation factor-like protein 13B isoform X1.	0.521
AHI1	NPHP3	A0A384AUJ6	A0A384A0W1	Jouberin isoform X1.	Nephrocystin-3 isoform X1.	0.418
ARL13B	AHI1	A0A383YMX6	A0A384AUJ6	ADP-ribosylation factor-like protein 13B isoform X1.	Jouberin isoform X1.	0.521
ARL13B	C2CD3	A0A383YMX6	A0A452CB71	ADP-ribosylation factor-like protein 13B isoform X1.	C2 domain-containing protein 3 isoform X1.	0.699
ARL13B	IFT52	A0A383YMX6	A0A384B1J0	ADP-ribosylation factor-like protein 13B isoform X1.	Intraflagellar transport protein 52 homolog isoform X1.	0.666
ARL13B	IFT57	A0A383YMX6	A0A384AIL9	ADP-ribosylation factor-like protein 13B isoform X1.	Intraflagellar transport protein 57 homolog.	0.690
ARL13B	IHH	A0A383YMX6	A0A384AKW1	ADP-ribosylation factor-like protein 13B isoform X1.	Indian hedgehog protein.	0.580
ARL13B	NPHP3	A0A383YMX6	A0A384A0W1	ADP-ribosylation factor-like protein 13B isoform X1.	Nephrocystin-3 isoform X1.	0.720
ARL13B	PKD2	A0A383YMX6	A0A452CIE9	ADP-ribosylation factor-like protein 13B isoform X1.	Polycystin-2.	0.752
ARL13B	SHH	A0A383YMX6	A0A452CFB9	ADP-ribosylation factor-like protein 13B isoform X1.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.583
ARL13B	SMO	A0A383YMX6	A0A452CD94	ADP-ribosylation factor-like protein 13B isoform X1.	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.	0.786
ARL13B	SUFU	A0A383YMX6	A0A384AJ11	ADP-ribosylation factor-like protein 13B isoform X1.	Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]	0.436
C2CD3	ARL13B	A0A452CB71	A0A383YMX6	C2 domain-containing protein 3 isoform X1.	ADP-ribosylation factor-like protein 13B isoform X1.	0.699
CCDC103	CCDC39	A0A383ZYN7	A0A384B700	Coiled-coil domain-containing protein 103.	Coiled-coil domain-containing protein 39.	0.741
CCDC103	CCDC40	A0A383ZYN7	A0A384AF32	Coiled-coil domain-containing protein 103.	Coiled-coil domain-containing protein 40.	0.762
CCDC103	DNAAF1	A0A383ZYN7	A0A384A5W4	Coiled-coil domain-containing protein 103.	Dynein assembly factor 1, axonemal.	0.786
CCDC39	CCDC103	A0A384B700	A0A383ZYN7	Coiled-coil domain-containing protein 39.	Coiled-coil domain-containing protein 103.	0.741
CCDC39	CCDC40	A0A384B700	A0A384AF32	Coiled-coil domain-containing protein 39.	Coiled-coil domain-containing protein 40.	0.779
CCDC39	DNAAF1	A0A384B700	A0A384A5W4	Coiled-coil domain-containing protein 39.	Dynein assembly factor 1, axonemal.	0.525
CCDC40	CCDC103	A0A384AF32	A0A383ZYN7	Coiled-coil domain-containing protein 40.	Coiled-coil domain-containing protein 103.	0.762