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BMP6 BMP6 VHL VHL LOC103016465 LOC103016465 LOC114238582 LOC114238582 LOC103017032 LOC103017032 LOC103012535 LOC103012535 LOC103016806 LOC103016806 LOC114237893 LOC114237893 PAX4 PAX4 SMO SMO FGF2 FGF2 TP63 TP63 NOTCH1 NOTCH1 IL31RA IL31RA GATA6 GATA6 CDH2 CDH2 SIDT2 SIDT2 CDK6 CDK6 HES1 HES1 CLCN2 CLCN2 CAV1 CAV1 ONECUT1 ONECUT1 LHX3 LHX3 CTNNB1 CTNNB1 HNF4A HNF4A BMP4 BMP4 LOC103001360 LOC103001360 HIF1A HIF1A NKX2-2 NKX2-2 BMP2 BMP2 RFX6 RFX6 NEUROD1 NEUROD1 EXT1 EXT1 FGF8 FGF8 BMP5 BMP5 BHLHA15 BHLHA15 SPDEF SPDEF DLL1 DLL1 SOX9 SOX9 LOC103017465 LOC103017465 NKX6-3 NKX6-3 GPAT4 GPAT4 PDPK1 PDPK1 PAX6 PAX6 GDF11 GDF11 RARG RARG FOXA1 FOXA1 RARA RARA NFIB NFIB PROX1 PROX1 LOC103006469 LOC103006469 RARB RARB NKX6-2 NKX6-2 SLC9A4 SLC9A4 HOXA5 HOXA5 LOC103013017 LOC103013017 WDR77 WDR77 NKX6-1 NKX6-1 NR5A2 NR5A2 ASCL1 ASCL1 AGR2 AGR2 PDX1 PDX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP6Bone morphogenetic protein 6. (388 aa)
VHLVon Hippel-Lindau disease tumor suppressor. (166 aa)
LOC103016465LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
LOC114238582Frizzled-5-like. (204 aa)
LOC103017032LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (320 aa)
LOC103012535LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (481 aa)
LOC103016806LOW QUALITY PROTEIN: retinoic acid receptor beta-like. (358 aa)
LOC114237893Myelin transcription factor 1. (270 aa)
PAX4LOW QUALITY PROTEIN: paired box protein Pax-4. (373 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
IL31RALOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha. (653 aa)
GATA6Transcription factor GATA-6. (357 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (887 aa)
SIDT2SID1 transmembrane family member 2 isoform X1. (839 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
HES1Transcription factor HES-1. (280 aa)
CLCN2Chloride channel protein 2 isoform X1. (891 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ONECUT1One cut domain family member. (470 aa)
LHX3LIM/homeobox protein Lhx3. (493 aa)
CTNNB1Catenin beta-1. (767 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (474 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
RFX6DNA-binding protein RFX6. (928 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (138 aa)
SPDEFSAM pointed domain-containing Ets transcription factor. (337 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
SOX9Transcription factor SOX-9. (432 aa)
LOC103017465Fatty acid synthase-like isoform X1. (3457 aa)
NKX6-3Homeobox protein Nkx-6.3. (357 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4 isoform X1. (456 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
GDF11Growth/differentiation factor 11. (418 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (433 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
RARBRetinoic acid receptor beta. (584 aa)
NKX6-2Homeobox protein Nkx-6.2. (120 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
LOC103013017RNA-binding protein 4. (363 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
NKX6-1Homeobox protein Nkx-6.1. (366 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (495 aa)
ASCL1Achaete-scute homolog 1. (169 aa)
AGR2Anterior gradient protein 2 homolog. (175 aa)
PDX1LOW QUALITY PROTEIN: pancreas/duodenum homeobox protein 1. (280 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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