STRINGSTRING
BMPR1A BMPR1A PRDM1 PRDM1 CPLANE1 CPLANE1 SAV1 SAV1 LOC103001360 LOC103001360 BMP4 BMP4 WNT11 WNT11 FRS2 FRS2 HES1 HES1 TGFBR1 TGFBR1 SMAD4 SMAD4 SMAD7 SMAD7 STRA6 STRA6 PTK7 PTK7 TRIP11 TRIP11 NOTCH1 NOTCH1 APLNR APLNR MATR3 MATR3 EGLN1 EGLN1 NOG NOG LOC103006490 LOC103006490 HEYL HEYL SMAD6 SMAD6 GATA3 GATA3 RBM15 RBM15 TBX5 TBX5 SLIT3 SLIT3 HOXA13 HOXA13 ZFPM1 ZFPM1 CCN1 CCN1 LOC103006469 LOC103006469 LUZP1 LUZP1 PROX1 PROX1 TBX3 TBX3 FZD2 FZD2 HECTD1 HECTD1 NSD2 NSD2 NPRL3 NPRL3 GJA5 GJA5 HEG1 HEG1 XIRP2 XIRP2 LRP2 LRP2 SALL4 SALL4 DCTN5 DCTN5 SUFU SUFU ZFPM2 ZFPM2 NKX2-5 NKX2-5 BMPR2 BMPR2 HEY2 HEY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PRDM1PR domain zinc finger protein 1. (672 aa)
CPLANE1Ciliogenesis and planar polarity effector 1 isoform X7. (3250 aa)
SAV1Protein salvador homolog 1. (351 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
HES1Transcription factor HES-1. (280 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
STRA6Receptor for retinol uptake STRA6 isoform X1. (685 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
TRIP11LOW QUALITY PROTEIN: thyroid receptor-interacting protein 11. (1980 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (400 aa)
MATR3Matrin-3 isoform X2. (511 aa)
EGLN1Egl nine homolog 1 isoform X1. (225 aa)
NOGNoggin. (154 aa)
LOC103006490LOW QUALITY PROTEIN: sal-like protein 4. (901 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
SMAD6Mothers against decapentaplegic homolog. (321 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
RBM15RNA-binding protein 15. (962 aa)
TBX5T-box transcription factor TBX5 isoform X1. (536 aa)
SLIT3Slit homolog 3 protein isoform X1. (1523 aa)
HOXA13Homeobox protein Hox-A13. (294 aa)
ZFPM1Zinc finger protein ZFPM1. (874 aa)
CCN1Protein CYR61. (382 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
LUZP1Leucine zipper protein 1. (1071 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
TBX3T-box transcription factor TBX3. (670 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
HECTD1LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HECTD1. (2609 aa)
NSD2Histone-lysine N-methyltransferase NSD2 isoform X4. (1358 aa)
NPRL3GATOR complex protein NPRL3 isoform X1. (569 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
HEG1Protein HEG homolog 1. (1339 aa)
XIRP2Xin actin-binding repeat-containing protein 2 isoform X1. (3319 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4651 aa)
SALL4Sal-like protein 4. (1068 aa)
DCTN5Dynactin subunit 5. (182 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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