STRINGSTRING
TGFBR1 TGFBR1 TGFB3 TGFB3 TGFBR2 TGFBR2 FERMT2 FERMT2 ENG ENG TGFB2 TGFB2 TGFBRAP1 TGFBRAP1 TGFBR3L TGFBR3L LRG1 LRG1 LOC103005758 LOC103005758 LOC103002500 LOC103002500 SMAD6 SMAD6 SMAD3 SMAD3 TGFBR3 TGFBR3 SMAD7 SMAD7 TGFB1 TGFB1 RASL11B RASL11B USP15 USP15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
TGFB3Transforming growth factor beta-3 proprotein. (456 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
FERMT2Fermitin family homolog 2 isoform X1. (706 aa)
ENGEndoglin isoform X1. (652 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TGFBRAP1Transforming growth factor-beta receptor-associated protein 1 isoform X1. (866 aa)
TGFBR3LLOW QUALITY PROTEIN: transforming growth factor-beta receptor type 3-like protein. (478 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
LOC103005758Left-right determination factor 2. (226 aa)
LOC103002500Left-right determination factor. (367 aa)
SMAD6Mothers against decapentaplegic homolog. (321 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X1. (863 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
RASL11BRas-like protein family member 11B. (248 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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