STRINGSTRING
SMAD4 SMAD4 ONECUT2 ONECUT2 ARRB2 ARRB2 ZMIZ1 ZMIZ1 LOC103007964 LOC103007964 LOC103008157 LOC103008157 ITGB5 ITGB5 LTBP3 LTBP3 TGFB1 TGFB1 NODAL NODAL SMAD9 SMAD9 LTBP4 LTBP4 GLG1 GLG1 CDH5 CDH5 PML PML SKIL SKIL SMAD7 SMAD7 SMAD2 SMAD2 TGFBR1 TGFBR1 LPXN LPXN CLDN5 CLDN5 TWSG1 TWSG1 COL3A1 COL3A1 COL1A2 COL1A2 CAV2 CAV2 ONECUT1 ONECUT1 ENG ENG SRC SRC LOC103014668 LOC103014668 ZFYVE9 ZFYVE9 LOC103001311 LOC103001311 APPL2 APPL2 CHST11 CHST11 SMAD3 SMAD3 SMAD6 SMAD6 SIRT1 SIRT1 TGFBR3L TGFBR3L PXN PXN MSTN MSTN NRROS NRROS SMAD5 SMAD5 TGFB2 TGFB2 LOC103010651 LOC103010651 LOC103007744 LOC103007744 FLCN FLCN TGFBR3 TGFBR3 WFIKKN2 WFIKKN2 HIPK2 HIPK2 LOC102997405 LOC102997405 ADAM9 ADAM9 ACVRL1 ACVRL1 USP15 USP15 ACVR1 ACVR1 ITGB8 ITGB8 NLK NLK FUT8 FUT8 TGFB3 TGFB3 ZYX ZYX LOC103015599 LOC103015599 CITED1 CITED1 FOXH1 FOXH1 USP9X USP9X LRRC32 LRRC32 TAB1 TAB1 SMAD1 SMAD1 MTMR4 MTMR4 PTPRK PTPRK TGFBR2 TGFBR2 APPL1 APPL1 HPGD HPGD FERMT2 FERMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD4Mothers against decapentaplegic homolog. (553 aa)
ONECUT2One cut domain family member. (433 aa)
ARRB2Beta-arrestin-2 isoform X1. (287 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1 isoform X1. (1071 aa)
LOC103007964EP300-interacting inhibitor of differentiation 2. (203 aa)
LOC103008157Signal transducer and activator of transcription. (793 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LTBP3LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 3. (1209 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
NODALNodal homolog. (280 aa)
SMAD9Mothers against decapentaplegic homolog. (440 aa)
LTBP4LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 4. (1391 aa)
GLG1LOW QUALITY PROTEIN: Golgi apparatus protein 1. (1204 aa)
CDH5Cadherin-5 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
PMLProtein PML isoform X1. (871 aa)
SKILSki-like protein isoform X2. (684 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
LPXNLeupaxin isoform X1; Belongs to the paxillin family. (392 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
TWSG1Twisted gastrulation protein homolog 1 isoform X1. (223 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (170 aa)
ONECUT1One cut domain family member. (470 aa)
ENGEndoglin isoform X1. (652 aa)
SRCTyrosine-protein kinase. (557 aa)
LOC103014668Transcription factor AP-1; Belongs to the bZIP family. (253 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1423 aa)
LOC103001311Transcription factor AP-1-like. (199 aa)
APPL2DCC-interacting protein 13-beta isoform X1. (662 aa)
CHST11Carbohydrate sulfotransferase. (347 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SMAD6Mothers against decapentaplegic homolog. (321 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
TGFBR3LLOW QUALITY PROTEIN: transforming growth factor-beta receptor type 3-like protein. (478 aa)
PXNPaxillin; Belongs to the paxillin family. (599 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
NRROSTransforming growth factor beta activator LRRC33. (692 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC103010651N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase isoform X1. (456 aa)
LOC103007744N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase-like. (264 aa)
FLCNFolliculin isoform X1. (579 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X1. (863 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (527 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1207 aa)
LOC102997405Signal transducer and activator of transcription. (783 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (819 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
TGFB3Transforming growth factor beta-3 proprotein. (456 aa)
ZYXZyxin isoform X1. (589 aa)
LOC103015599Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2559 aa)
CITED1LOW QUALITY PROTEIN: cbp/p300-interacting transactivator 1. (200 aa)
FOXH1Forkhead box protein H1. (360 aa)
USP9XProbable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2577 aa)
LRRC32Transforming growth factor beta activator LRRC32. (663 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (506 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1210 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1461 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
APPL1DCC-interacting protein 13-alpha isoform X1. (672 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]. (145 aa)
FERMT2Fermitin family homolog 2 isoform X1. (706 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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