STRINGSTRING
RASGRP1 RASGRP1 RHOV RHOV PRKD1 PRKD1 ARHGAP5 ARHGAP5 KPNB1 KPNB1 CNKSR1 CNKSR1 RHOH RHOH RACGAP1 RACGAP1 RAPGEF3 RAPGEF3 CDK2 CDK2 RASGRF2 RASGRF2 RASGRP4 RASGRP4 ERAS ERAS CUNH15orf62 CUNH15orf62 BRAP BRAP KSR2 KSR2 PPP1R21 PPP1R21 NCKAP1 NCKAP1 WASF1 WASF1 ROCK1 ROCK1 RASGRP3 RASGRP3 BRK1 BRK1 SOS2 SOS2 RHOJ RHOJ AIF1 AIF1 RALGDS RALGDS RALGPS1 RALGPS1 KRAS KRAS TMEM19 TMEM19 RAP1B RAP1B RAB21 RAB21 ELMO1 ELMO1 BCL6 BCL6 RFXANK RFXANK LOC102997675 LOC102997675 ROCK2 ROCK2 COL1A2 COL1A2 ARHGDIB ARHGDIB EPS8 EPS8 RAB12 RAB12 RERG RERG ARHGEF12 ARHGEF12 LOC103019571 LOC103019571 CDKN1A CDKN1A RAB4B RAB4B RASGRP2 RASGRP2 RAP2C RAP2C NISCH NISCH RRAS2 RRAS2 LOC103018737 LOC103018737 PDPN PDPN CDC42 CDC42 LOC103013709 LOC103013709 LOC103015276 LOC103015276 TRIM28 TRIM28 RAPGEF1 RAPGEF1 LOC103009504 LOC103009504 RRAS RRAS GPSM2 GPSM2 DNMT1 DNMT1 LOC103016648 LOC103016648 DOK3 DOK3 EPS8L2 EPS8L2 GNA12 GNA12 RGL1 RGL1 LOC103000260 LOC103000260 LOC103016504 LOC103016504 ITGA3 ITGA3 DGKI DGKI CTNNAL1 CTNNAL1 LOC114237157 LOC114237157 WAS WAS RAB33A RAB33A CDC42EP5 CDC42EP5 KSR1 KSR1 NGFR NGFR TAX1BP3 TAX1BP3 RAPGEFL1 RAPGEFL1 RAPGEF5 RAPGEF5 SYNJ2BP SYNJ2BP FARP2 FARP2 SYNGAP1 SYNGAP1 LOC103005203 LOC103005203 LOC103000875 LOC103000875 LOC114238716 LOC114238716 LOC103005590 LOC103005590 NF1 NF1 LOC103001290 LOC103001290 LOC103014668 LOC103014668 RAP2B RAP2B LOC103001311 LOC103001311 KIAA0355 KIAA0355 RASGEF1B RASGEF1B CDC42EP1 CDC42EP1 RAC2 RAC2 PLEKHG7 PLEKHG7 HACD3 HACD3 CUNH12orf74 CUNH12orf74 PLEKHG5 PLEKHG5 RANGRF RANGRF SOS1 SOS1 CDC42EP3 CDC42EP3 RASGRF1 RASGRF1 ADGRG1 ADGRG1 DOK2 DOK2 ARHGAP35 ARHGAP35 RHOA RHOA LOC102998293 LOC102998293 RASSF1 RASSF1 LOC102997638 LOC102997638 NRAS NRAS EPS8L3 EPS8L3 RAP1A RAP1A CSF1 CSF1 MRAS MRAS USP8 USP8 WASF2 WASF2 USP50 USP50 PHACTR4 PHACTR4 RASGEF1A RASGEF1A LOC103004363 LOC103004363 CDC42EP2 CDC42EP2 HRAS HRAS MAPKAPK5 MAPKAPK5 RAB35 RAB35 RIT1 RIT1 ARHGEF11 ARHGEF11 IQGAP3 IQGAP3 CCNA2 CCNA2 RAB33B RAB33B RIT2 RIT2 SHTN1 SHTN1 RHOG RHOG NKIRAS1 NKIRAS1 RALB RALB EPS8L1 EPS8L1 PDIA2 PDIA2 ARHGDIG ARHGDIG RAB9A RAB9A RHOU RHOU RAB4A RAB4A CDH13 CDH13 CYFIP1 CYFIP1 RAPGEF4 RAPGEF4 LOC103019676 LOC103019676 DOK1 DOK1 LOC103005459 LOC103005459 LOC103013083 LOC103013083 RAB15 RAB15 RAB39B RAB39B RAB39A RAB39A RAB9B RAB9B GDI1 GDI1 GNA13 GNA13 CDC42EP4 CDC42EP4 ARHGDIA ARHGDIA RAC3 RAC3 LAT LAT RABGEF1 RABGEF1 RAC1 RAC1 RB1 RB1 RGL2 RGL2 PLCE1 PLCE1 RAB30 RAB30 DBNL DBNL RALA RALA AGTR1 AGTR1 RALGPS2 RALGPS2 SGSM3 SGSM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (797 aa)
RHOVRho-related GTP-binding protein RhoV. (236 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
ARHGAP5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
KPNB1Importin subunit beta-1. (731 aa)
CNKSR1Connector enhancer of kinase suppressor of ras 1 isoform X1. (710 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X1. (936 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
RASGRP4RAS guanyl-releasing protein 4. (660 aa)
ERASGTPase ERas. (233 aa)
CUNH15orf62Uncharacterized protein C15orf62 homolog, mitochondrial. (175 aa)
BRAPBRCA1-associated protein isoform X1. (592 aa)
KSR2Kinase suppressor of Ras 2. (949 aa)
PPP1R21Protein phosphatase 1 regulatory subunit 21 isoform X1. (780 aa)
NCKAP1Nck-associated protein 1 isoform X2. (1102 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
RASGRP3Ras guanyl-releasing protein 3 isoform X1. (740 aa)
BRK1Protein BRICK1. (75 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1272 aa)
RHOJRho-related GTP-binding protein RhoJ. (236 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
RALGDSLOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator. (813 aa)
RALGPS1Ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X1. (608 aa)
KRASGTPase KRas isoform X3. (227 aa)
TMEM19Transmembrane protein 19. (358 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
RAB21Ras-related protein Rab-21. (222 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
RFXANKDNA-binding protein RFXANK isoform X1. (260 aa)
LOC102997675LOW QUALITY PROTEIN: unconventional myosin-IXb-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2021 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (200 aa)
EPS8LOW QUALITY PROTEIN: epidermal growth factor receptor kinase substrate 8. (818 aa)
RAB12Ras-related protein Rab-12. (221 aa)
RERGRas-related and estrogen-regulated growth inhibitor. (199 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1545 aa)
LOC103019571Zinc finger protein 304. (590 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
RAB4BRas-related protein Rab-4B. (153 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X3. (608 aa)
RAP2CRas-related protein Rap-2c isoform X1. (183 aa)
NISCHNischarin isoform X1. (1532 aa)
RRAS2Ras-related protein R-Ras2. (169 aa)
LOC103018737Ras-related protein Rap-1b-like isoform X1. (142 aa)
PDPNPodoplanin isoform X1. (162 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
LOC103013709Zinc finger protein 304-like. (660 aa)
LOC103015276Zinc finger protein 304-like. (689 aa)
TRIM28Transcription intermediary factor 1-beta. (700 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1238 aa)
LOC103009504LOW QUALITY PROTEIN: cdc42 effector protein 3-like. (254 aa)
RRASRas-related protein R-Ras. (251 aa)
GPSM2G-protein-signaling modulator 2 isoform X1. (681 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1348 aa)
LOC103016648LOW QUALITY PROTEIN: alpha-catulin-like. (620 aa)
DOK3Docking protein 3. (338 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2. (421 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (253 aa)
RGL1Ral guanine nucleotide dissociation stimulator-like 1. (814 aa)
LOC103000260Ras-related protein Rap-2a-like. (200 aa)
LOC103016504LOW QUALITY PROTEIN: ras-related protein R-Ras2-like. (260 aa)
ITGA3Integrin alpha-3; Belongs to the integrin alpha chain family. (1048 aa)
DGKIDiacylglycerol kinase. (731 aa)
CTNNAL1Alpha-catulin. (623 aa)
LOC114237157Alpha-catulin-like. (141 aa)
WASwiskott-Aldrich syndrome protein. (516 aa)
RAB33ARas-related protein Rab-33A isoform X1. (241 aa)
CDC42EP5Cdc42 effector protein 5. (148 aa)
KSR1Kinase suppressor of Ras 1 isoform X1. (842 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
RAPGEFL1Rap guanine nucleotide exchange factor-like 1. (559 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (612 aa)
SYNJ2BPSynaptojanin-2-binding protein. (145 aa)
FARP2FERM, ARHGEF and pleckstrin domain-containing protein 2. (1678 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1384 aa)
LOC103005203LOW QUALITY PROTEIN: cdc42 effector protein 3-like. (303 aa)
LOC103000875NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
LOC114238716Cadherin EGF LAG seven-pass G-type receptor 1-like isoform X1. (79 aa)
LOC103005590Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2674 aa)
NF1Neurofibromin. (2821 aa)
LOC103001290NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (191 aa)
LOC103014668Transcription factor AP-1; Belongs to the bZIP family. (253 aa)
RAP2BRas-related protein Rap-2b. (183 aa)
LOC103001311Transcription factor AP-1-like. (199 aa)
KIAA0355Uncharacterized protein KIAA0355 homolog isoform X1. (1070 aa)
RASGEF1Bras-GEF domain-containing family member 1B isoform X1. (479 aa)
CDC42EP1Cdc42 effector protein 1. (361 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
PLEKHG7Pleckstrin homology domain-containing family G member 7. (532 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
CUNH12orf74LOW QUALITY PROTEIN: uncharacterized protein C12orf74 homolog. (295 aa)
PLEKHG5Pleckstrin homology domain-containing family G member 5 isoform X1. (1049 aa)
RANGRFRan guanine nucleotide release factor isoform X1. (186 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1001 aa)
CDC42EP3Cdc42 effector protein 3. (254 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1. (1257 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (686 aa)
DOK2Docking protein 2 isoform X1. (411 aa)
ARHGAP35Rho GTPase-activating protein 35 isoform X1. (1500 aa)
RHOATransforming protein RhoA. (193 aa)
LOC102998293Death domain-containing membrane protein NRADD-like isoform X1. (303 aa)
RASSF1Ras association domain-containing protein 1. (295 aa)
LOC102997638DNA (Cytosine-5)-methyltransferase 1-like. (185 aa)
NRASGTPase NRas. (189 aa)
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (594 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
MRASRas-related protein M-Ras isoform X1. (208 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1087 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
USP50Inactive ubiquitin carboxyl-terminal hydrolase 50; Belongs to the peptidase C19 family. (373 aa)
PHACTR4Phosphatase and actin regulator. (725 aa)
RASGEF1Aras-GEF domain-containing family member 1A. (491 aa)
LOC103004363Ral guanine nucleotide dissociation stimulator-like. (128 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
HRASGTPase HRas isoform X1. (196 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (473 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
RIT1GTP-binding protein Rit1. (218 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform X1. (1587 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1612 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (435 aa)
RAB33BRas-related protein Rab-33B. (229 aa)
RIT2LOW QUALITY PROTEIN: GTP-binding protein Rit2. (223 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
RHOGRho-related GTP-binding protein RhoG. (191 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
RALBRas-related protein Ral-B isoform X1. (163 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (757 aa)
PDIA2Protein disulfide-isomerase A2 isoform X1. (528 aa)
ARHGDIGRho GDP-dissociation inhibitor 3. (212 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
RHOURho-related GTP-binding protein RhoU. (188 aa)
RAB4ARas-related protein Rab-4A. (113 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (858 aa)
LOC103019676Rho-related GTP-binding protein RhoG-like. (191 aa)
DOK1Docking protein 1 isoform X1. (483 aa)
LOC103005459Rap guanine nucleotide exchange factor 2. (1407 aa)
LOC103013083Rap guanine nucleotide exchange factor 6-like isoform X1. (183 aa)
RAB15Ras-related protein Rab-15 isoform X1. (212 aa)
RAB39BRas-related protein Rab-39B. (213 aa)
RAB39ARas-related protein Rab-39A. (217 aa)
RAB9BRas-related protein Rab-9B. (201 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (425 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
CDC42EP4Cdc42 effector protein 4. (355 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (204 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (206 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (261 aa)
RABGEF1Rab5 GDP/GTP exchange factor isoform X1. (783 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (194 aa)
RB1Retinoblastoma-associated protein. (816 aa)
RGL2Ral guanine nucleotide dissociation stimulator-like 2. (779 aa)
PLCE1Phosphoinositide phospholipase C. (1973 aa)
RAB30Ras-related protein Rab-30. (203 aa)
DBNLDrebrin-like protein isoform X1. (448 aa)
RALARas-related protein Ral-A. (206 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
RALGPS2Ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1. (583 aa)
SGSM3Small G protein signaling modulator 3. (747 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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