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| | LRP2 | Low-density lipoprotein receptor-related protein 2. (4651 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | LOC103016503 | Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa) |
| | LOC103013794 | Peroxisomal multifunctional enzyme type 2-like. (190 aa) |
| | EBPL | Emopamil-binding protein-like. (189 aa) |
| | LOC103015178 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (469 aa) |
| | SULT1E1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (300 aa) |
| | GC | Vitamin D-binding protein. (475 aa) |
| | LOC103000983 | 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa) |
| | FDFT1 | Squalene synthase isoform X1. (417 aa) |
| | AMACR | alpha-methylacyl-CoA racemase. (386 aa) |
| | LOC103016570 | Peroxisomal multifunctional enzyme type 2-like. (121 aa) |
| | ATP8B1 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1273 aa) |
| | SCP2D1 | SCP2 sterol-binding domain-containing protein 1. (156 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa) |
| | ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa) |
| | LOC103005044 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (254 aa) |
| | HSD17B7 | 3-keto-steroid reductase isoform X1. (334 aa) |
| | DHRS11 | Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | LOC103000968 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (498 aa) |
| | SDR42E2 | Putative short-chain dehydrogenase/reductase family 42E member 2. (417 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (487 aa) |
| | CLN8 | Protein CLN8. (284 aa) |
| | SQLE | Squalene monooxygenase. (574 aa) |
| | SOAT1 | O-acyltransferase. (550 aa) |
| | LOC102999025 | Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (537 aa) |
| | TSKU | Tsukushin isoform X1. (367 aa) |
| | LOC103016735 | Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (523 aa) |
| | LOC103016462 | Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (461 aa) |
| | LOC103007900 | Steroid 17-alpha-hydroxylase/17,20 lyase isoform X1; Belongs to the cytochrome P450 family. (509 aa) |
| | SCHIP1 | Schwannomin-interacting protein 1 isoform X1. (260 aa) |
| | HSD17B8 | Estradiol 17-beta-dehydrogenase 8. (259 aa) |
| | TMEM130 | Transmembrane protein 130 isoform X1. (435 aa) |
| | HSD3B7 | 3 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa) |
| | LOC103002038 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (311 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial. (523 aa) |
| | MECP2 | methyl-CpG-binding protein 2. (459 aa) |
| | LOC103015403 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa) |
| | HDLBP | Vigilin. (1268 aa) |
| | LOC103011957 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (631 aa) |
| | ERG28 | Probable ergosterol biosynthetic protein 28. (140 aa) |
| | NPC2 | NPC intracellular cholesterol transporter 2. (149 aa) |
| | HSD17B10 | 3-hydroxyacyl-CoA dehydrogenase type-2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | SPP1 | Osteopontin. (303 aa) |
| | HNF1A | Hepatocyte nuclear factor 1-alpha isoform X1. (632 aa) |
| | NFE2L1 | Endoplasmic reticulum membrane sensor NFE2L1 isoform X1. (778 aa) |
| | NSDHL | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (361 aa) |
| | ABCB11 | Bile salt export pump isoform X1. (1326 aa) |
| | LOC103017184 | Cytochrome P450 27C1; Belongs to the cytochrome P450 family. (466 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (265 aa) |
| | LOC103010534 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (278 aa) |
| | APOB | Apolipoprotein B-100. (4585 aa) |
| | DHRS9 | Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa) |
| | ABCA2 | ATP-binding cassette sub-family A member 2. (2133 aa) |
| | VLDLR | Very low-density lipoprotein receptor. (920 aa) |
| | LOC102997223 | LOW QUALITY PROTEIN: dehydrogenase/reductase SDR family member 2, mitochondrial-like. (217 aa) |
| | APOF | LOW QUALITY PROTEIN: apolipoprotein F. (315 aa) |
| | LOC103009132 | LOW QUALITY PROTEIN: retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | SHH | LOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa) |
| | LOC103016150 | Retinol dehydrogenase 16-like. (182 aa) |
| | SDR9C7 | Short-chain dehydrogenase/reductase family 9C member 7 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa) |
| | LOC102998237 | LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B-like. (745 aa) |
| | LOC103015198 | LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B-like. (786 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | LIMD2 | LIM domain-containing protein 2. (128 aa) |
| | MBTPS2 | Membrane-bound transcription factor site-2 protease. (506 aa) |
| | LIPE | LOW QUALITY PROTEIN: hormone-sensitive lipase. (1040 aa) |
| | LDLR | Low-density lipoprotein receptor. (842 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein 5. (1080 aa) |
| | LRP5L | LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein. (469 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (655 aa) |
| | APP | Amyloid-beta precursor protein isoform X1. (735 aa) |
| | LEPR | Leptin receptor isoform X4. (1166 aa) |
| | SCP2 | Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9. (723 aa) |
| | DHCR24 | Delta(24)-sterol reductase. (516 aa) |
| | TIPARP | Protein mono-ADP-ribosyltransferase TIPARP isoform X1. (657 aa) |
| | LOC103001949 | Histidine triad nucleotide-binding protein 2, mitochondrial-like. (162 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (276 aa) |
| | NR1H4 | Bile acid receptor isoform X1. (486 aa) |
| | LIPC | Hepatic triacylglycerol lipase. (500 aa) |
| | LOC103009357 | Cytochrome P450 11B1, mitochondrial; Belongs to the cytochrome P450 family. (412 aa) |
| | LBR | lamin-B receptor isoform X1. (630 aa) |
| | LOC103006319 | Cytochrome P450 1A2-like; Belongs to the cytochrome P450 family. (159 aa) |
| | LOC103004066 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa) |
| | ACBD3 | Golgi resident protein GCP60 isoform X1. (408 aa) |
| | NR5A2 | Nuclear receptor subfamily 5 group A member 2. (495 aa) |
| | LOC103002145 | Dihydrodiol dehydrogenase 3 isoform X1. (323 aa) |
| | LOC103003050 | Aldo-keto reductase family 1 member C3 homolog isoform X1. (324 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | LOC103001239 | Retinol dehydrogenase 16-like. (233 aa) |
| | HSD17B14 | 17-beta-hydroxysteroid dehydrogenase 14. (270 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | LOC102998844 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa) |
| | LOC103014598 | 25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (468 aa) |
| | SCAP | Sterol regulatory element-binding protein cleavage-activating protein isoform X1. (1280 aa) |
| | RDH8 | Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | LOC103015346 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (373 aa) |
| | ANGPTL3 | LOW QUALITY PROTEIN: angiopoietin-related protein 3. (465 aa) |
| | CDCP2 | CUB domain-containing protein 2. (540 aa) |
| | LOC102999763 | LOW QUALITY PROTEIN: very-long-chain 3-oxoacyl-CoA reductase-B-like. (339 aa) |
| | LOC114235831 | Estrogen receptor-like. (144 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (437 aa) |
| | ABCD3 | ATP-binding cassette sub-family D member 3 isoform X1. (678 aa) |
| | ERLIN2 | Erlin-2 isoform X1. (368 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (231 aa) |
| | SLC27A2 | Very long-chain acyl-CoA synthetase. (620 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (218 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | APOA2 | Apolipoprotein A-II isoform X1. (103 aa) |
| | BDH1 | LOW QUALITY PROTEIN: D-beta-hydroxybutyrate dehydrogenase, mitochondrial. (297 aa) |
| | FDPS | Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family. (421 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (400 aa) |
| | ABCG1 | ATP-binding cassette sub-family G member 1 isoform X1. (678 aa) |
| | FDX1 | Adrenodoxin, mitochondrial. (134 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa) |
| | LOC103008223 | NADH-cytochrome b5 reductase 2-like. (305 aa) |
| | ARV1 | Protein ARV1. (284 aa) |
| | STS | Steryl-sulfatase isoform X1. (578 aa) |
| | SREBF1 | LOW QUALITY PROTEIN: sterol regulatory element-binding protein 1. (1119 aa) |
| | TM7SF2 | Delta(14)-sterol reductase. (399 aa) |
| | CCDC160 | Coiled-coil domain-containing protein 160. (325 aa) |
| | LOC103007249 | Vitamin D 25-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa) |
| | SLC27A5 | LOW QUALITY PROTEIN: bile acyl-CoA synthetase. (690 aa) |
| | LOC102997198 | Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa) |
| | MSMO1 | Methylsterol monooxygenase 1 isoform X1; Belongs to the sterol desaturase family. (293 aa) |
| | HSD17B3 | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa) |
| | AKR1D1 | 3-oxo-5-beta-steroid 4-dehydrogenase isoform X1. (326 aa) |
| | STARD3 | stAR-related lipid transfer protein 3 isoform X1. (513 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1578 aa) |
| | LOC103002194 | Glucose-6-phosphatase-like. (366 aa) |
| | LOC103019221 | Estradiol 17-beta-dehydrogenase 1-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | LOC103010774 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) |
| | LOC103008831 | ATP-binding cassette sub-family A member 1-like. (119 aa) |
| | ABCA1 | ATP-binding cassette sub-family A member 1 isoform X1. (2264 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | PMVK | Phosphomevalonate kinase. (192 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | LOC103014370 | Cholesterol 24-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa) |
| | LIPA | Lysosomal acid lipase/cholesteryl ester hydrolase isoform X1. (482 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa) |
| | LIMA1 | LIM domain and actin-binding protein 1 isoform X1. (761 aa) |
| | SOAT2 | O-acyltransferase. (535 aa) |
| | LOC103002469 | Apolipoprotein F-like. (254 aa) |
| | LOC103009423 | Retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | LOC103001013 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (508 aa) |
| | RDH5 | 11-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa) |
| | LOC103008169 | 17-beta-hydroxysteroid dehydrogenase type 6 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa) |
| | LOC103009326 | Alpha-fetoprotein. (610 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | EBP | LOW QUALITY PROTEIN: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase. (233 aa) |
| | LOC103020890 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like. (194 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | LOC103017836 | Dehydrogenase/reductase SDR family member 4 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | LOC102997517 | Dehydrogenase/reductase SDR family member 2, mitochondrial-like. (150 aa) |
| | HSD17B12 | Very-long-chain 3-oxoacyl-CoA reductase isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | CACNA1H | LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2326 aa) |
| | TECR | Very-long-chain enoyl-CoA reductase. (344 aa) |
| | HSDL1 | Inactive hydroxysteroid dehydrogenase-like protein 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | SDR42E1 | Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa) |
| | HSD17B2 | Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa) |
| | LOC103008068 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (327 aa) |
| | APOA5 | Apolipoprotein A-V isoform X1. (378 aa) |
| | ESR1 | LOW QUALITY PROTEIN: estrogen receptor. (422 aa) |
| | LOC103014627 | Uncharacterized protein LOC103014627 isoform X1. (142 aa) |
| | LOC103003841 | Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (529 aa) |
| | LOC103004502 | LOW QUALITY PROTEIN: serum paraoxonase/arylesterase 1. (319 aa) |
| | LOC103007308 | Isopentenyl-diphosphate Delta-isomerase 1. (195 aa) |
| | LCAT | Phosphatidylcholine-sterol acyltransferase. (440 aa) |
| | HSD11B2 | Corticosteroid 11-beta-dehydrogenase isozyme 2. (509 aa) |
| | SCNN1B | Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa) |
| | LOC103008057 | Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa) |
| | CLN6 | Ceroid-lipofuscinosis neuronal protein 6. (473 aa) |
| | LOC103011342 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa) |
| | LOC103007560 | Cytochrome P450 1A2 isoform X1; Belongs to the cytochrome P450 family. (516 aa) |
| | CHST10 | Carbohydrate sulfotransferase. (356 aa) |
| | GBA2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (925 aa) |
| | HINT2 | Histidine triad nucleotide-binding protein 2, mitochondrial isoform X1. (151 aa) |
| | SC5D | Lathosterol oxidase; Belongs to the sterol desaturase family. (299 aa) |
| | SLC37A4 | Glucose-6-phosphate exchanger SLC37A4 isoform X1. (451 aa) |
| | APOA4 | Apolipoprotein A-IV. (380 aa) |
| | CUBN | Cubilin isoform X1. (3619 aa) |
| | LOC103016126 | Peroxisomal multifunctional enzyme type 2-like. (145 aa) |
