STRINGSTRING
NOTCH1 NOTCH1 FGF10 FGF10 FRS2 FRS2 LOC103015737 LOC103015737 CTNNB1 CTNNB1 BMP4 BMP4 OTX2 OTX2 LOC103001360 LOC103001360 TASOR TASOR FAM76B FAM76B AHI1 AHI1 CUNH2orf66 CUNH2orf66 HEY2 HEY2 PGAP1 PGAP1 SIX2 SIX2 LHX1 LHX1 TTC8 TTC8 CDX1 CDX1 TDRD5 TDRD5 CDX4 CDX4 LDB1 LDB1 TBX6 TBX6 ARL13B ARL13B HSPB11 HSPB11 SMAD6 SMAD6 RNF2 RNF2 FAM76A FAM76A TIFAB TIFAB DCANP1 DCANP1 NEUROG1 NEUROG1 WNT8A WNT8A MTHFSD MTHFSD TDRD1 TDRD1 PLD6 PLD6 GPC3 GPC3 BMPR1A BMPR1A LOC103006469 LOC103006469 VAX2 VAX2 WNT3 WNT3 ZIC3 ZIC3 CER1 CER1 TDRKH TDRKH TDRD10 TDRD10 WNT1 WNT1 DDIT3 DDIT3 TBX3 TBX3 BCOR BCOR PAX6 PAX6 EPB41L5 EPB41L5 CHRDL1 CHRDL1 AXIN1 AXIN1 SFRP1 SFRP1 NRARP NRARP DLL1 DLL1 LOC103016465 LOC103016465 LOC114238582 LOC114238582 WNT6 WNT6 LOC103017032 LOC103017032 COBL COBL LOC103002330 LOC103002330 LOC103012535 LOC103012535 SHH SHH SMO SMO PTCH1 PTCH1 LOC103017945 LOC103017945 C2CD3 C2CD3 NOTCH2 NOTCH2 NODAL NODAL PCSK6 PCSK6 SRF SRF LOC103006421 LOC103006421 TDRD6 TDRD6 TDRD15 TDRD15 MDFI MDFI TDRD7 TDRD7 SMAD4 SMAD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2379 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
LOC103015737Mesoderm posterior protein 1. (126 aa)
CTNNB1Catenin beta-1. (767 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
OTX2Homeobox protein OTX2. (289 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
TASORProtein TASOR isoform X1. (1672 aa)
FAM76BProtein FAM76B isoform X1. (366 aa)
AHI1Jouberin isoform X1. (1197 aa)
CUNH2orf66Uncharacterized protein C2orf66 homolog. (118 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
TTC8Tetratricopeptide repeat protein 8 isoform X1. (505 aa)
CDX1Homeobox protein CDX-1. (144 aa)
TDRD5LOW QUALITY PROTEIN: tudor domain-containing protein 5. (1051 aa)
CDX4Homeobox protein CDX-4. (283 aa)
LDB1LIM domain-binding protein 1 isoform X2. (375 aa)
TBX6T-box transcription factor TBX6. (436 aa)
ARL13BADP-ribosylation factor-like protein 13B isoform X1. (430 aa)
HSPB11Intraflagellar transport protein 25 homolog isoform X1. (151 aa)
SMAD6Mothers against decapentaplegic homolog. (321 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (344 aa)
FAM76AProtein FAM76A. (307 aa)
TIFABTRAF-interacting protein with FHA domain-containing protein B. (207 aa)
DCANP1LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (128 aa)
NEUROG1Neurogenin-1. (244 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MTHFSDMethenyltetrahydrofolate synthase domain-containing protein isoform X1. (384 aa)
TDRD1Tudor domain-containing protein 1. (1047 aa)
PLD6Mitochondrial cardiolipin hydrolase. (187 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (504 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
VAX2Ventral anterior homeobox 2. (340 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ZIC3Zinc finger protein ZIC 3. (163 aa)
CER1Cerberus. (273 aa)
TDRKHTudor and KH domain-containing protein isoform X1. (561 aa)
TDRD10LOW QUALITY PROTEIN: tudor domain-containing protein 10. (383 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
TBX3T-box transcription factor TBX3. (670 aa)
BCORBCL-6 corepressor isoform X1. (1757 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
EPB41L5Band 4.1-like protein 5. (805 aa)
CHRDL1Chordin-like protein 1 isoform X1. (379 aa)
AXIN1Axin-1 isoform X1. (866 aa)
SFRP1Secreted frizzled-related protein 1. (295 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (719 aa)
LOC103016465LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
LOC114238582Frizzled-5-like. (204 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
LOC103017032LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (320 aa)
COBLProtein cordon-bleu isoform X1. (1383 aa)
LOC103002330LOW QUALITY PROTEIN: BCL-6 corepressor-like. (1668 aa)
LOC103012535LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (481 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (837 aa)
PTCH1LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
LOC103017945Tetratricopeptide repeat protein 8-like. (451 aa)
C2CD3C2 domain-containing protein 3 isoform X1. (2349 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
NODALNodal homolog. (280 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (844 aa)
SRFSerum response factor. (464 aa)
LOC103006421LOW QUALITY PROTEIN: homeobox protein CDX-1-like. (151 aa)
TDRD6Tudor domain-containing protein 6. (1955 aa)
TDRD15LOW QUALITY PROTEIN: tudor domain-containing protein 15. (2083 aa)
MDFImyoD family inhibitor. (246 aa)
TDRD7Tudor domain-containing protein 7. (1098 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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