STRINGSTRING
RNF2 RNF2 LOC103016465 LOC103016465 LOC114238582 LOC114238582 LOC103017032 LOC103017032 LOC103012535 LOC103012535 SHH SHH NODAL NODAL PCSK6 PCSK6 SRF SRF LOC103006421 LOC103006421 TDRD6 TDRD6 TDRD15 TDRD15 TDRD7 TDRD7 SMAD4 SMAD4 FRS2 FRS2 LOC103015737 LOC103015737 CTNNB1 CTNNB1 BMP4 BMP4 OTX2 OTX2 LOC103001360 LOC103001360 TASOR TASOR FAM76B FAM76B CUNH2orf66 CUNH2orf66 HEY2 HEY2 PGAP1 PGAP1 SIX2 SIX2 LHX1 LHX1 CDX1 CDX1 TDRD5 TDRD5 CDX4 CDX4 LDB1 LDB1 TBX6 TBX6 NRARP NRARP EPB41L5 EPB41L5 TBX3 TBX3 DDIT3 DDIT3 TDRD10 TDRD10 TDRKH TDRKH CER1 CER1 ZIC3 ZIC3 WNT3 WNT3 LOC103006469 LOC103006469 GPC3 GPC3 PLD6 PLD6 TDRD1 TDRD1 MTHFSD MTHFSD WNT8A WNT8A NEUROG1 NEUROG1 DCANP1 DCANP1 TIFAB TIFAB FAM76A FAM76A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (344 aa)
LOC103016465LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
LOC114238582Frizzled-5-like. (204 aa)
LOC103017032LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (320 aa)
LOC103012535LOW QUALITY PROTEIN: frizzled-5-like; Belongs to the G-protein coupled receptor Fz/Smo family. (481 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
NODALNodal homolog. (280 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (844 aa)
SRFSerum response factor. (464 aa)
LOC103006421LOW QUALITY PROTEIN: homeobox protein CDX-1-like. (151 aa)
TDRD6Tudor domain-containing protein 6. (1955 aa)
TDRD15LOW QUALITY PROTEIN: tudor domain-containing protein 15. (2083 aa)
TDRD7Tudor domain-containing protein 7. (1098 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
LOC103015737Mesoderm posterior protein 1. (126 aa)
CTNNB1Catenin beta-1. (767 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
OTX2Homeobox protein OTX2. (289 aa)
LOC103001360Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (204 aa)
TASORProtein TASOR isoform X1. (1672 aa)
FAM76BProtein FAM76B isoform X1. (366 aa)
CUNH2orf66Uncharacterized protein C2orf66 homolog. (118 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1. (337 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
SIX2Homeobox protein SIX2 isoform X1. (298 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
CDX1Homeobox protein CDX-1. (144 aa)
TDRD5LOW QUALITY PROTEIN: tudor domain-containing protein 5. (1051 aa)
CDX4Homeobox protein CDX-4. (283 aa)
LDB1LIM domain-binding protein 1 isoform X2. (375 aa)
TBX6T-box transcription factor TBX6. (436 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
EPB41L5Band 4.1-like protein 5. (805 aa)
TBX3T-box transcription factor TBX3. (670 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
TDRD10LOW QUALITY PROTEIN: tudor domain-containing protein 10. (383 aa)
TDRKHTudor and KH domain-containing protein isoform X1. (561 aa)
CER1Cerberus. (273 aa)
ZIC3Zinc finger protein ZIC 3. (163 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC103006469Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (152 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (504 aa)
PLD6Mitochondrial cardiolipin hydrolase. (187 aa)
TDRD1Tudor domain-containing protein 1. (1047 aa)
MTHFSDMethenyltetrahydrofolate synthase domain-containing protein isoform X1. (384 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
NEUROG1Neurogenin-1. (244 aa)
DCANP1LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (128 aa)
TIFABTRAF-interacting protein with FHA domain-containing protein B. (207 aa)
FAM76AProtein FAM76A. (307 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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