STRINGSTRING
TBC1D23 TBC1D23 CHMP2B CHMP2B LEPROT LEPROT ZFYVE9 ZFYVE9 EPS15 EPS15 LAPTM4B LAPTM4B ANKRD27 ANKRD27 GGA1 GGA1 WASHC4 WASHC4 ARL1 ARL1 SNX1 SNX1 RAB11A RAB11A RASSF9 RASSF9 RAB8B RAB8B GOLT1A GOLT1A MICALL1 MICALL1 VPS28 VPS28 SCRIB SCRIB HEATR5B HEATR5B DENND1B DENND1B VPS35 VPS35 MAGEL2 MAGEL2 VPS26A VPS26A CHMP7 CHMP7 EHD2 EHD2 PICALM PICALM PTPN23 PTPN23 DENND1C DENND1C UBXN6 UBXN6 CCDC93 CCDC93 RAB11B RAB11B KIAA1107 KIAA1107 SNX7 SNX7 SORT1 SORT1 VAMP3 VAMP3 WASHC1 WASHC1 RAB6B RAB6B AP5B1 AP5B1 SNX32 SNX32 TBC1D10C TBC1D10C TBC1D10A TBC1D10A RAB35 RAB35 VTA1 VTA1 BET1L BET1L ANKRD50 ANKRD50 CHMP1A CHMP1A TRAPPC10 TRAPPC10 PQLC1 PQLC1 FAM45A FAM45A VTI1A VTI1A CALY CALY REPS2 REPS2 LOC103019725 LOC103019725 TMEM87A TMEM87A VPS39 VPS39 LAMTOR1 LAMTOR1 RAB6A RAB6A EHD1 EHD1 VPS51 VPS51 STX5 STX5 LOC103013139 LOC103013139 SNX8 SNX8 CHMP3 CHMP3 ARHGAP44 ARHGAP44 CHMP2A CHMP2A AP3B1 AP3B1 WASHC2C WASHC2C SNF8 SNF8 SPAG9 SPAG9 AP3D1 AP3D1 PLEKHJ1 PLEKHJ1 RNF126 RNF126 CHMP5 CHMP5 DENND2A DENND2A ANKFY1 ANKFY1 SGSM2 SGSM2 LOC103013898 LOC103013898 LOC102997878 LOC102997878 RAB14 RAB14 SNX27 SNX27 LOC103008831 LOC103008831 ABCA1 ABCA1 RAB13 RAB13 TMEM50A TMEM50A LOC103004798 LOC103004798 TRIM27 TRIM27 RAB7A RAB7A BLOC1S1 BLOC1S1 ZFYVE16 ZFYVE16 CORO1C CORO1C HEATR5A HEATR5A SNX6 SNX6 CHMP4A CHMP4A ARHGAP1 ARHGAP1 SRL SRL RAB11FIP3 RAB11FIP3 SNX5 SNX5 RAB9A RAB9A STX10 STX10 RIC1 RIC1 CCDC22 CCDC22 SNX4 SNX4 RAB29 RAB29 LAPTM4A LAPTM4A VPS26B VPS26B EPS15L1 EPS15L1 RAB8A RAB8A SNX12 SNX12 ITSN1 ITSN1 TMEM50B TMEM50B VPS26C VPS26C RILP RILP VPS53 VPS53 VTI1B VTI1B RAB17 RAB17 TBC1D17 TBC1D17 RAB9B RAB9B CHMP4C CHMP4C ARFRP1 ARFRP1 STX16 STX16 ATP6AP1 ATP6AP1 TEX28 TEX28 CHMP6 CHMP6 HGS HGS CLN5 CLN5 LMTK2 LMTK2 AP5Z1 AP5Z1 VPS52 VPS52 LRRC1 LRRC1 GCC2 GCC2 LOC103015993 LOC103015993 BLOC1S2 BLOC1S2 LOC102998380 LOC102998380 RAB18 RAB18 SNX2 SNX2 CLEC16A CLEC16A RAB7B RAB7B WASHC5 WASHC5 DCTN1 DCTN1 PHETA2 PHETA2 VPS29 VPS29 VPS54 VPS54 PREPL PREPL CLTC CLTC NSG2 NSG2 SNX3 SNX3 REPS1 REPS1 NSG1 NSG1 RAB10 RAB10 EHD3 EHD3 DPY30 DPY30 CMTM6 CMTM6 VPS4B VPS4B GRIP2 GRIP2 RBSN RBSN TMCC1 TMCC1 ARF6 ARF6 AP5M1 AP5M1 CHMP4B CHMP4B VPS36 VPS36 ENTR1 ENTR1 DENND1A DENND1A GOLT1B GOLT1B MVB12A MVB12A VPS16 VPS16 AP5S1 AP5S1 STAM STAM CHMP1B CHMP1B RGP1 RGP1 SNX33 SNX33 MYO5B MYO5B VPS4A VPS4A LOC103007471 LOC103007471 ANKRD63 ANKRD63 SNX18 SNX18 VPS50 VPS50 EPG5 EPG5 VCP VCP TMEM87B TMEM87B ALS2CL ALS2CL LYST LYST TBC1D14 TBC1D14 LOC103006170 LOC103006170 MICALL2 MICALL2 SNX30 SNX30 LOC103010806 LOC103010806 GRIP1 GRIP1 LOC103012508 LOC103012508 WAS WAS EHD4 EHD4 BAIAP3 BAIAP3 ABCA2 ABCA2 LOC114238097 LOC114238097 TRARG1 TRARG1 RAB22A RAB22A UBE2O UBE2O SNX9 SNX9 TBC1D10B TBC1D10B YKT6 YKT6 STX6 STX6 VPS35L VPS35L RAB11FIP4 RAB11FIP4 ALS2 ALS2 LOC103011888 LOC103011888 LOC103014437 LOC103014437 LOC103006169 LOC103006169
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBC1D23TBC1 domain family member 23 isoform X1. (701 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
LEPROTLeptin receptor gene-related protein. (131 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1423 aa)
EPS15Epidermal growth factor receptor substrate 15 isoform X1. (762 aa)
LAPTM4BLysosomal-associated transmembrane protein 4B. (207 aa)
ANKRD27Ankyrin repeat domain-containing protein 27 isoform X1. (1071 aa)
GGA1ADP-ribosylation factor-binding protein GGA1 isoform X1. (636 aa)
WASHC4WASH complex subunit 4 isoform X1. (1173 aa)
ARL1ADP-ribosylation factor-like protein 1 isoform X1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
SNX1Sorting nexin-1. (522 aa)
RAB11ARas-related protein Rab-11A. (216 aa)
RASSF9Ras association domain-containing protein 9. (436 aa)
RAB8BRas-related protein Rab-8B. (181 aa)
GOLT1AVesicle transport protein GOT1A. (132 aa)
MICALL1MICAL-like protein 1. (821 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1610 aa)
HEATR5BHEAT repeat-containing protein 5B isoform X1. (2078 aa)
DENND1BDENN domain-containing protein 1B isoform X1. (663 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
MAGEL2MAGE-like protein 2. (1182 aa)
VPS26AVacuolar protein sorting-associated protein 26A isoform X1. (329 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
EHD2EH domain-containing protein 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (713 aa)
PTPN23Tyrosine-protein phosphatase non-receptor type 23. (1628 aa)
DENND1CDENN domain-containing protein 1C. (801 aa)
UBXN6UBX domain-containing protein 6. (388 aa)
CCDC93Coiled-coil domain-containing protein 93. (628 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
KIAA1107AP2-interacting clathrin-endocytosis protein. (1352 aa)
SNX7Sorting nexin-7 isoform X1. (451 aa)
SORT1Sortilin. (694 aa)
VAMP3Vesicle-associated membrane protein 3. (110 aa)
WASHC1WASH complex subunit 1 isoform X1. (491 aa)
RAB6BRas-related protein Rab-6B. (208 aa)
AP5B1AP-5 complex subunit beta-1. (877 aa)
SNX32Sorting nexin-32 isoform X1. (439 aa)
TBC1D10CCarabin. (446 aa)
TBC1D10ATBC1 domain family member 10A. (537 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
VTA1Vacuolar protein sorting-associated protein VTA1 homolog isoform X1. (309 aa)
BET1LBET1-like protein isoform X1. (115 aa)
ANKRD50Ankyrin repeat domain-containing protein 50. (1428 aa)
CHMP1ACharged multivesicular body protein 1a. (267 aa)
TRAPPC10Trafficking protein particle complex subunit 10 isoform X1. (1161 aa)
PQLC1PQ-loop repeat-containing protein 1. (270 aa)
FAM45AProtein FAM45A isoform X1. (357 aa)
VTI1AVesicle transport through interaction with t-SNAREs homolog 1A isoform X1. (224 aa)
CALYNeuron-specific vesicular protein calcyon. (151 aa)
REPS2ralBP1-associated Eps domain-containing protein 2 isoform X1. (522 aa)
LOC103019725Glutamate receptor-interacting protein 2-like. (142 aa)
TMEM87ATransmembrane protein 87A isoform X1. (556 aa)
VPS39vam6/Vps39-like protein. (875 aa)
LAMTOR1Ragulator complex protein LAMTOR1 isoform X1. (161 aa)
RAB6ARas-related protein Rab-6A. (208 aa)
EHD1EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
VPS51Vacuolar protein sorting-associated protein 51 homolog isoform X1. (781 aa)
STX5Syntaxin-5 isoform X1; Belongs to the syntaxin family. (355 aa)
LOC103013139HEAT repeat-containing protein 5A-like. (174 aa)
SNX8Sorting nexin-8. (411 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
ARHGAP44Rho GTPase-activating protein 44. (799 aa)
CHMP2ACharged multivesicular body protein 2a isoform X1. (222 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1086 aa)
WASHC2CWASH complex subunit 2C isoform X1. (1338 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
SPAG9C-Jun-amino-terminal kinase-interacting protein 4 isoform X1. (1338 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1140 aa)
PLEKHJ1Pleckstrin homology domain-containing family J member 1. (112 aa)
RNF126E3 ubiquitin-protein ligase RNF126. (212 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
DENND2ADENN domain-containing protein 2A isoform X2. (1117 aa)
ANKFY1Rabankyrin-5 isoform X1. (1170 aa)
SGSM2Small G protein signaling modulator 2 isoform X1. (1050 aa)
LOC103013898Ras-related protein Rab-5C. (216 aa)
LOC102997878Vacuolar protein-sorting-associated protein 25. (176 aa)
RAB14Ras-related protein Rab-14. (215 aa)
SNX27Sorting nexin-27 isoform X2. (542 aa)
LOC103008831ATP-binding cassette sub-family A member 1-like. (119 aa)
ABCA1ATP-binding cassette sub-family A member 1 isoform X1. (2264 aa)
RAB13Ras-related protein Rab-13. (203 aa)
TMEM50ATransmembrane protein 50A isoform X1. (177 aa)
LOC103004798Annexin. (341 aa)
TRIM27LOW QUALITY PROTEIN: zinc finger protein RFP. (517 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
BLOC1S1Biogenesis of lysosome-related organelles complex 1 subunit 1. (213 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X1. (1563 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
HEATR5AHEAT repeat-containing protein 5A isoform X1. (2054 aa)
SNX6Sorting nexin-6 isoform X1. (294 aa)
CHMP4ACharged multivesicular body protein 4a. (222 aa)
ARHGAP1Rho GTPase-activating protein 1. (433 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
RAB11FIP3Rab11 family-interacting protein 3. (473 aa)
SNX5Sorting nexin-5. (455 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
STX10Syntaxin-10 isoform X1. (249 aa)
RIC1RAB6A-GEF complex partner protein 1 isoform X1. (1341 aa)
CCDC22Coiled-coil domain-containing protein 22. (525 aa)
SNX4Sorting nexin-4. (450 aa)
RAB29Ras-related protein Rab-7L1 isoform X1. (205 aa)
LAPTM4ALysosomal-associated transmembrane protein 4A. (233 aa)
VPS26BVacuolar protein sorting-associated protein 26B. (391 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1 isoform X1. (870 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
SNX12Sorting nexin-12 isoform X1. (162 aa)
ITSN1Intersectin-1 isoform X5. (1716 aa)
TMEM50BTransmembrane protein 50B. (158 aa)
VPS26CDown syndrome critical region protein 3. (297 aa)
RILPRab-interacting lysosomal protein isoform X1. (392 aa)
VPS53Vacuolar protein sorting-associated protein 53 homolog. (832 aa)
VTI1BVesicle transport through interaction with t-SNAREs homolog 1B isoform X1. (232 aa)
RAB17Ras-related protein Rab-17 isoform X1. (213 aa)
TBC1D17TBC1 domain family member 17. (650 aa)
RAB9BRas-related protein Rab-9B. (201 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
ARFRP1ADP-ribosylation factor-related protein 1 isoform X1. (201 aa)
STX16LOW QUALITY PROTEIN: syntaxin-16. (317 aa)
ATP6AP1V-type proton ATPase subunit S1. (468 aa)
TEX28Testis-specific protein TEX28. (426 aa)
CHMP6Charged multivesicular body protein 6. (190 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (773 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5. (273 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X1. (1497 aa)
AP5Z1AP-5 complex subunit zeta-1. (806 aa)
VPS52Vacuolar protein sorting-associated protein 52 homolog isoform X1. (723 aa)
LRRC1Leucine-rich repeat-containing protein 1. (649 aa)
GCC2GRIP and coiled-coil domain-containing protein 2 isoform X1. (1680 aa)
LOC103015993Charged multivesicular body protein 1b-2. (199 aa)
BLOC1S2Biogenesis of lysosome-related organelles complex 1 subunit 2. (142 aa)
LOC102998380Vacuolar protein sorting-associated protein 29-like. (89 aa)
RAB18Ras-related protein Rab-18. (206 aa)
SNX2Sorting nexin-2 isoform X1. (523 aa)
CLEC16AProtein CLEC16A isoform X1. (1050 aa)
RAB7BRas-related protein Rab-7b isoform X1. (205 aa)
WASHC5WASH complex subunit 5. (1159 aa)
DCTN1Dynactin subunit 1 isoform X1. (1281 aa)
PHETA2Sesquipedalian-2. (262 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
VPS54Vacuolar protein sorting-associated protein 54 isoform X1. (977 aa)
PREPLProlyl endopeptidase-like isoform X1. (727 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
NSG2Neuronal vesicle trafficking-associated protein 2. (171 aa)
SNX3Sorting nexin-3. (162 aa)
REPS1ralBP1-associated Eps domain-containing protein 1 isoform X2. (744 aa)
NSG1Neuronal vesicle trafficking-associated protein 1 isoform X1. (185 aa)
RAB10Ras-related protein Rab-10. (200 aa)
EHD3EH domain-containing protein 3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
DPY30Protein dpy-30 homolog. (99 aa)
CMTM6CKLF-like MARVEL transmembrane domain-containing protein 6. (178 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
GRIP2Glutamate receptor-interacting protein 2. (1043 aa)
RBSNRabenosyn-5. (784 aa)
TMCC1Transmembrane and coiled-coil domains protein 1 isoform X1. (659 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
AP5M1AP-5 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (498 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
VPS36Vacuolar protein-sorting-associated protein 36. (328 aa)
ENTR1Endosome-associated-trafficking regulator 1. (374 aa)
DENND1ADENN domain-containing protein 1A isoform X1. (1069 aa)
GOLT1BVesicle transport protein GOT1B isoform X1. (138 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (873 aa)
AP5S1AP-5 complex subunit sigma-1. (199 aa)
STAMSignal transducing adapter molecule 1. (529 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
RGP1RAB6A-GEF complex partner protein 2. (391 aa)
SNX33Sorting nexin. (574 aa)
MYO5BUnconventional myosin-Vb isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1837 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (526 aa)
LOC103007471Ras-related protein Rab-7b-like isoform X1. (145 aa)
ANKRD63LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 63. (283 aa)
SNX18Sorting nexin-18. (495 aa)
VPS50Syndetin isoform X4. (969 aa)
EPG5LOW QUALITY PROTEIN: ectopic P granules protein 5 homolog. (2506 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (761 aa)
TMEM87BTransmembrane protein 87B. (562 aa)
ALS2CLALS2 C-terminal-like protein isoform X1. (946 aa)
LYSTLysosomal-trafficking regulator. (3864 aa)
TBC1D14LOW QUALITY PROTEIN: TBC1 domain family member 14. (700 aa)
LOC103006170DENN domain-containing protein 5A. (630 aa)
MICALL2LOW QUALITY PROTEIN: MICAL-like protein 2. (1031 aa)
SNX30Sorting nexin-30. (504 aa)
LOC103010806LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 26A-like. (251 aa)
GRIP1Glutamate receptor-interacting protein 1 isoform X1. (1070 aa)
LOC103012508Synaptobrevin homolog YKT6-like isoform X1; Belongs to the synaptobrevin family. (198 aa)
WASwiskott-Aldrich syndrome protein. (516 aa)
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (653 aa)
BAIAP3BAI1-associated protein 3 isoform X1. (1152 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2133 aa)
LOC114238097Intersectin-2-like. (356 aa)
TRARG1Trafficking regulator of GLUT4 1 isoform X1. (206 aa)
RAB22ARas-related protein Rab-22A. (152 aa)
UBE2OLOW QUALITY PROTEIN: (E3-independent) E2 ubiquitin-conjugating enzyme. (1138 aa)
SNX9Sorting nexin. (624 aa)
TBC1D10BTBC1 domain family member 10B isoform X1. (662 aa)
YKT6Synaptobrevin homolog YKT6; Belongs to the synaptobrevin family. (159 aa)
STX6Syntaxin-6 isoform X1; Belongs to the syntaxin family. (322 aa)
VPS35LUPF0505 protein C16orf62 homolog isoform X1. (969 aa)
RAB11FIP4Rab11 family-interacting protein 4. (558 aa)
ALS2LOW QUALITY PROTEIN: alsin. (1680 aa)
LOC103011888LOW QUALITY PROTEIN: Alstrom syndrome protein 1-like. (309 aa)
LOC103014437LOW QUALITY PROTEIN: signal transducing adapter molecule 1-like. (520 aa)
LOC103006169Sorting nexin; Involved in several stages of intracellular trafficking. (411 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (12%) [HD]