STRINGSTRING
LOC103003050 LOC103003050 LOC103002145 LOC103002145 LOC103004066 LOC103004066 LOC103006319 LOC103006319 ALKBH3 ALKBH3 BBOX1 BBOX1 HMOX2 HMOX2 JMJD8 JMJD8 DEGS1 DEGS1 PTGS2 PTGS2 LOC103009357 LOC103009357 LOC103011863 LOC103011863 KDM6B KDM6B PAH PAH HMOX1 HMOX1 SCD5 SCD5 LOC103010111 LOC103010111 NOS3 NOS3 FMO4 FMO4 FMO2 FMO2 FMO1 FMO1 LOC103015497 LOC103015497 AGMO AGMO KDM4A KDM4A P3H1 P3H1 LOC103000297 LOC103000297 LOC103000849 LOC103000849 RIOX2 RIOX2 TSTD2 TSTD2 LOC102997685 LOC102997685 KDM1B KDM1B SC5D SC5D LOC103007560 LOC103007560 LOC103011342 LOC103011342 LOC103019841 LOC103019841 LOC103008057 LOC103008057 KDM5B KDM5B EGLN2 EGLN2 HIF1AN HIF1AN LOC102998555 LOC102998555 KDM7A KDM7A TBXAS1 TBXAS1 LOC103001000 LOC103001000 AKR1D1 AKR1D1 LOC103012783 LOC103012783 LOC103007855 LOC103007855 EGLN3 EGLN3 METTL26 METTL26 PHF2 PHF2 FMO5 FMO5 KMO KMO LOC103017184 LOC103017184 NOS2 NOS2 KDM5C KDM5C COQ6 COQ6 RIOX1 RIOX1 ALKBH1 ALKBH1 LOC103015403 LOC103015403 LOC102998454 LOC102998454 PTGIS PTGIS JMJD6 JMJD6 P4HB P4HB FADS6 FADS6 OGFOD3 OGFOD3 KDM8 KDM8 PLOD3 PLOD3 ALKBH4 ALKBH4 LOC103014682 LOC103014682 LOC103007900 LOC103007900 SCD SCD LOC103017669 LOC103017669 LOC103018236 LOC103018236 LOC103016462 LOC103016462 LOC103016735 LOC103016735 PHF8 PHF8 LOC103009652 LOC103009652 LOC102999025 LOC102999025 PLOD2 PLOD2 COQ7 COQ7 P4HA2 P4HA2 SQLE SQLE TET3 TET3 KDM4C KDM4C LOC103007607 LOC103007607 OGFOD2 OGFOD2 PHYH PHYH TYW5 TYW5 LOC103012933 LOC103012933 MICAL1 MICAL1 TET2 TET2 MOXD1 MOXD1 LOC103020180 LOC103020180 CRTAP CRTAP PAM PAM LOC103000983 LOC103000983 LOC103015178 LOC103015178 LOC103014952 LOC103014952 LOC103019174 LOC103019174 LOC103019435 LOC103019435 LOC103019987 LOC103019987 KDM2B KDM2B NOS1 NOS1 LOC102999115 LOC102999115 PHYHD1 PHYHD1 LOC102999399 LOC102999399 LOC103007461 LOC103007461 LOC103016503 LOC103016503 P3H2 P3H2 TPH2 TPH2 LOC102999435 LOC102999435 JMJD7 JMJD7 ALKBH2 ALKBH2 LOC103001013 LOC103001013 CH25H CH25H DEGS2 DEGS2 LOC103014370 LOC103014370 MICAL3 MICAL3 LOC102997313 LOC102997313 PTGS1 PTGS1 LOC103003841 LOC103003841 LOC103011560 LOC103011560 DBH DBH TET1 TET1 LOC114236145 LOC114236145 LOC103017679 LOC103017679 LOC103014389 LOC103014389 P3H3 P3H3 EGLN1 EGLN1 LOC103006468 LOC103006468 LOC103010196 LOC103010196 KDM6A KDM6A LOC103004611 LOC103004611 TMLHE TMLHE MSMO1 MSMO1 TYRP1 TYRP1 DOHH DOHH HSPBAP1 HSPBAP1 LOC102997198 LOC102997198 KDM3A KDM3A LOC103007249 LOC103007249 TPH1 TPH1 KDM1A KDM1A MICAL2 MICAL2 MICALCL MICALCL SAAL1 SAAL1 FADS1 FADS1 FADS3 FADS3 CCDC160 CCDC160 ALKBH5 ALKBH5 FADS2 FADS2 LOC102999883 LOC102999883 P4HA3 P4HA3 CCNDBP1 CCNDBP1 LOC103020472 LOC103020472 LOC102997947 LOC102997947 KDM2A KDM2A TH TH LOC103011787 LOC103011787 LOC103012080 LOC103012080 KDM5A KDM5A TTI2 TTI2 PLOD1 PLOD1 JMJD4 JMJD4 RSBN1 RSBN1 LOC103010326 LOC103010326 KDM4B KDM4B LOC103014598 LOC103014598 P4HTM P4HTM LOC102998844 LOC102998844 TYR TYR FTO FTO P4HA1 P4HA1 OGFOD1 OGFOD1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC103003050Aldo-keto reductase family 1 member C3 homolog isoform X1. (324 aa)
LOC103002145Dihydrodiol dehydrogenase 3 isoform X1. (323 aa)
LOC103004066Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
LOC103006319Cytochrome P450 1A2-like; Belongs to the cytochrome P450 family. (159 aa)
ALKBH3Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3. (281 aa)
BBOX1Gamma-butyrobetaine dioxygenase. (387 aa)
HMOX2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
JMJD8jmjC domain-containing protein 8 isoform X1. (258 aa)
DEGS1Sphingolipid delta(4)-desaturase DES1 isoform X1. (344 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
LOC103009357Cytochrome P450 11B1, mitochondrial; Belongs to the cytochrome P450 family. (412 aa)
LOC103011863Cytochrome P450 2G1; Belongs to the cytochrome P450 family. (494 aa)
KDM6BLOW QUALITY PROTEIN: lysine-specific demethylase 6B. (1504 aa)
PAHPhenylalanine-4-hydroxylase. (452 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
SCD5stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (308 aa)
LOC103010111Dimethylaniline monooxygenase [N-oxide-forming]. (534 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1206 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (577 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (539 aa)
LOC103015497Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (445 aa)
KDM4ALysine-specific demethylase 4A isoform X1. (1072 aa)
P3H1Prolyl 3-hydroxylase 1 isoform X1. (736 aa)
LOC103000297Taurochenodeoxycholic 6 alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
LOC103000849Taurochenodeoxycholic 6 alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family. (510 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (464 aa)
TSTD2Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2. (528 aa)
LOC102997685Cytidine monophosphate-N-acetylneuraminic acid hydroxylase. (525 aa)
KDM1BLysine-specific histone demethylase 1B isoform X1. (820 aa)
SC5DLathosterol oxidase; Belongs to the sterol desaturase family. (299 aa)
LOC103007560Cytochrome P450 1A2 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
LOC103011342Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC103019841stearoyl-CoA desaturase 5-like. (74 aa)
LOC103008057Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
KDM5BLOW QUALITY PROTEIN: lysine-specific demethylase 5B. (1390 aa)
EGLN2LOW QUALITY PROTEIN: egl nine homolog 2. (399 aa)
HIF1ANLOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor. (349 aa)
LOC102998555LOW QUALITY PROTEIN: cytochrome P450 2A13-like. (479 aa)
KDM7ALysine-specific demethylase 7A isoform X1. (685 aa)
TBXAS1thromboxane-A synthase; Belongs to the cytochrome P450 family. (533 aa)
LOC103001000LOW QUALITY PROTEIN: putative DBH-like monooxygenase protein 2. (618 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase isoform X1. (326 aa)
LOC103012783Endoplasmic reticulum protein SC65-like. (379 aa)
LOC103007855Endoplasmic reticulum protein SC65-like. (379 aa)
EGLN3Egl nine homolog 3. (239 aa)
METTL26Methyltransferase-like 26 isoform X1. (242 aa)
PHF2Lysine-specific demethylase PHF2. (981 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (493 aa)
LOC103017184Cytochrome P450 27C1; Belongs to the cytochrome P450 family. (466 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1157 aa)
KDM5CLysine-specific demethylase 5C. (1413 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (469 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (578 aa)
ALKBH1Nucleic acid dioxygenase ALKBH1 isoform X1. (390 aa)
LOC1030154031,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
LOC102998454Transmembrane protein 189. (271 aa)
PTGISProstacyclin synthase. (516 aa)
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X2. (414 aa)
P4HBProtein disulfide-isomerase. (510 aa)
FADS6Fatty acid desaturase 6. (323 aa)
OGFOD32-oxoglutarate and iron-dependent oxygenase domain-containing protein 3. (292 aa)
KDM8Bifunctional peptidase and arginyl-hydroxylase JMJD5. (406 aa)
PLOD3Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3. (739 aa)
ALKBH4Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4. (270 aa)
LOC103014682Cytochrome P450 3A29-like. (503 aa)
LOC103007900Steroid 17-alpha-hydroxylase/17,20 lyase isoform X1; Belongs to the cytochrome P450 family. (509 aa)
SCDacyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
LOC103017669Cytochrome P450 2C23-like; Belongs to the cytochrome P450 family. (504 aa)
LOC103018236Cytochrome P450 2C18-like. (254 aa)
LOC103016462Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (461 aa)
LOC103016735Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (523 aa)
PHF8Histone lysine demethylase PHF8 isoform X1. (1024 aa)
LOC103009652Lysine-specific demethylase 5C isoform X1. (1547 aa)
LOC102999025Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (537 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1. (759 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (216 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha-2 isoform X1. (558 aa)
SQLESqualene monooxygenase. (574 aa)
TET3Methylcytosine dioxygenase TET3 isoform X3. (1803 aa)
KDM4CLysine-specific demethylase 4C isoform X1. (1052 aa)
LOC103007607Cytochrome P450 2D14 isoform X1; Belongs to the cytochrome P450 family. (499 aa)
OGFOD22-oxoglutarate and iron-dependent oxygenase domain-containing protein 2. (349 aa)
PHYHphytanoyl-CoA dioxygenase, peroxisomal. (337 aa)
TYW5tRNA wybutosine-synthesizing protein 5 isoform X1. (315 aa)
LOC103012933Cytochrome P450 20A1. (462 aa)
MICAL1F-actin-monooxygenase MICAL1 isoform X1. (1085 aa)
TET2Methylcytosine dioxygenase TET2 isoform X1. (1991 aa)
MOXD1DBH-like monooxygenase protein 1. (543 aa)
LOC103020180Cytochrome P450 2U1; Belongs to the cytochrome P450 family. (543 aa)
CRTAPCartilage-associated protein. (401 aa)
PAMPeptidyl-glycine alpha-amidating monooxygenase isoform X1. (971 aa)
LOC1030009835-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
LOC10301517824-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (469 aa)
LOC103014952Cytochrome P450 3A24. (503 aa)
LOC103019174LOW QUALITY PROTEIN: phylloquinone omega-hydroxylase CYP4F2-like; Belongs to the cytochrome P450 family. (420 aa)
LOC103019435LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (375 aa)
LOC103019987LOW QUALITY PROTEIN: phylloquinone omega-hydroxylase CYP4F2-like. (327 aa)
KDM2BLysine-specific demethylase 2B isoform X1. (1223 aa)
NOS1LOW QUALITY PROTEIN: nitric oxide synthase, brain. (1590 aa)
LOC102999115LOW QUALITY PROTEIN: cytochrome P450 2F3. (433 aa)
PHYHD1phytanoyl-CoA dioxygenase domain-containing protein 1 isoform X1. (291 aa)
LOC102999399LOW QUALITY PROTEIN: cytochrome P450 2F2-like. (558 aa)
LOC103007461Cytochrome P450 2J6-like; Belongs to the cytochrome P450 family. (468 aa)
LOC103016503Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa)
P3H2Prolyl 3-hydroxylase 2. (533 aa)
TPH2Tryptophan 5-hydroxylase 2. (491 aa)
LOC102999435Alkylated DNA repair protein alkB homolog 8-like. (320 aa)
JMJD7Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 isoform X1. (341 aa)
ALKBH2DNA oxidative demethylase ALKBH2. (260 aa)
LOC10300101325-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (508 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa)
DEGS2Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1. (323 aa)
LOC103014370Cholesterol 24-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
MICAL3LOW QUALITY PROTEIN: F-actin-monooxygenase MICAL3. (2095 aa)
LOC102997313Prolyl 4-hydroxylase subunit alpha-2-like. (161 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (622 aa)
LOC103003841Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (529 aa)
LOC103011560LOW QUALITY PROTEIN: cytochrome P450 2S1-like; Belongs to the cytochrome P450 family. (494 aa)
DBHDopamine beta-hydroxylase. (610 aa)
TET1Methylcytosine dioxygenase TET1 isoform X1. (2167 aa)
LOC114236145Aspartyl/asparaginyl beta-hydroxylase-like. (484 aa)
LOC103017679Aspartyl/asparaginyl beta-hydroxylase isoform X1. (302 aa)
LOC103014389LOW QUALITY PROTEIN: cytochrome P450 2J2; Belongs to the cytochrome P450 family. (504 aa)
P3H3Prolyl 3-hydroxylase 3. (632 aa)
EGLN1Egl nine homolog 1 isoform X1. (225 aa)
LOC103006468Cytochrome P450 2W1. (506 aa)
LOC103010196LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor-like. (430 aa)
KDM6ALysine-specific demethylase 6A. (1180 aa)
LOC103004611LOW QUALITY PROTEIN: histone demethylase UTY-like. (1312 aa)
TMLHETrimethyllysine dioxygenase, mitochondrial. (317 aa)
MSMO1Methylsterol monooxygenase 1 isoform X1; Belongs to the sterol desaturase family. (293 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (303 aa)
HSPBAP1HSPB1-associated protein 1 isoform X1. (524 aa)
LOC102997198Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
KDM3ALysine-specific demethylase 3A. (1322 aa)
LOC103007249Vitamin D 25-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
TPH1Tryptophan 5-hydroxylase 1. (444 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (756 aa)
MICAL2F-actin-monooxygenase MICAL2 isoform X1. (1114 aa)
MICALCLMICAL C-terminal-like protein. (710 aa)
SAAL1Protein SAAL1 isoform X1. (474 aa)
FADS1acyl-CoA (8-3)-desaturase isoform X1. (360 aa)
FADS3Fatty acid desaturase 3. (486 aa)
CCDC160Coiled-coil domain-containing protein 160. (325 aa)
ALKBH5RNA demethylase ALKBH5. (353 aa)
FADS2acyl-CoA 6-desaturase. (413 aa)
LOC102999883Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (525 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha-3 isoform X1. (544 aa)
CCNDBP1cyclin-D1-binding protein 1. (358 aa)
LOC103020472Cytochrome P450 4F22; Belongs to the cytochrome P450 family. (531 aa)
LOC102997947Cytochrome P450 2E1 isoform X1; Belongs to the cytochrome P450 family. (495 aa)
KDM2ALysine-specific demethylase 2A. (1162 aa)
THTyrosine 3-monooxygenase. (500 aa)
LOC103011787Aromatase-like; Belongs to the cytochrome P450 family. (503 aa)
LOC103012080Aromatase; Belongs to the cytochrome P450 family. (503 aa)
KDM5ALysine-specific demethylase 5A isoform X1. (1689 aa)
TTI2TELO2-interacting protein 2 isoform X1. (508 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa)
JMJD42-oxoglutarate and iron-dependent oxygenase JMJD4 isoform X1. (467 aa)
RSBN1LOW QUALITY PROTEIN: lysine-specific demethylase 9. (804 aa)
LOC103010326Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
KDM4BLysine-specific demethylase 4B isoform X1. (1121 aa)
LOC10301459825-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (468 aa)
P4HTMTransmembrane prolyl 4-hydroxylase. (338 aa)
LOC102998844Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
TYRTyrosinase. (530 aa)
FTOAlpha-ketoglutarate-dependent dioxygenase FTO isoform X1. (519 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha-1 isoform X1. (534 aa)
OGFOD1Prolyl 3-hydroxylase OGFOD1 isoform X1. (543 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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