STRINGSTRING
CAMKV CAMKV GSK3A GSK3A PRKD2 PRKD2 LRRK2 LRRK2 TTK TTK CSNK2A2 CSNK2A2 CAMK1D CAMK1D PRKCQ PRKCQ LOC103000311 LOC103000311 NEK7 NEK7 HIPK4 HIPK4 AURKB AURKB CSNK1G1 CSNK1G1 CDK5 CDK5 MKNK1 MKNK1 MAST2 MAST2 PRKAA2 PRKAA2 LATS2 LATS2 CAMK1G CAMK1G RICTOR RICTOR MYO3A MYO3A MAPK12 MAPK12 PRKCZ PRKCZ LOC114238459 LOC114238459 SBK1 SBK1 PCK1 PCK1 PNCK PNCK STK39 STK39 MYO3B MYO3B IKBKB IKBKB PKD1 PKD1 TSSK4 TSSK4 DYRK1B DYRK1B CSNK1G2 CSNK1G2 MAPK7 MAPK7 RIPK1 RIPK1 PRKX PRKX TTBK2 TTBK2 PRKDC PRKDC MASTL MASTL MAPK13 MAPK13 LOC103006613 LOC103006613 SMTNL1 SMTNL1 MAP3K13 MAP3K13 STK38 STK38 ULK3 ULK3 PRKCI PRKCI LATS1 LATS1 TGFBR1 TGFBR1 GAS6 GAS6 TSSK1B TSSK1B MAPK1 MAPK1 TSSK6 TSSK6 MAST3 MAST3 LOC103010562 LOC103010562 DYRK3 DYRK3 IKBKE IKBKE DYRK2 DYRK2 LOC102999798 LOC102999798 NEK6 NEK6 PKN3 PKN3 STK32A STK32A TTBK1 TTBK1 DCLK1 DCLK1 CSNK2A1 CSNK2A1 SYK SYK PRKCH PRKCH STK4 STK4 LOC103001540 LOC103001540 SGK2 SGK2 PBK PBK CAMK1 CAMK1 CAMK4 CAMK4 PRKAA1 PRKAA1 BCL2 BCL2 DCLK3 DCLK3 ROCK1 ROCK1 LOC103002887 LOC103002887 SGK1 SGK1 STK32B STK32B CLK1 CLK1 RPS6KB1 RPS6KB1 CDK5R1 CDK5R1 PRKCE PRKCE VRK2 VRK2 LOC103005963 LOC103005963 PDGFB PDGFB CSNK1A1 CSNK1A1 SMG1 SMG1 ATR ATR CHUK CHUK BAK1 BAK1 LMTK2 LMTK2 EPO EPO PRKCB PRKCB PLK1 PLK1 RPS6KA2 RPS6KA2 CSNK1D CSNK1D PRKCA PRKCA AURKA AURKA LOC103003704 LOC103003704 VRK3 VRK3 CAB39 CAB39 NLK NLK DYRK1A DYRK1A MORC3 MORC3 TLK1 TLK1 AKT3 AKT3 CLSPN CLSPN PKN2 PKN2 PKN1 PKN1 PRKACA PRKACA GSK3B GSK3B DGKQ DGKQ PDPK1 PDPK1 PRKCG PRKCG SBK2 SBK2 ULK1 ULK1 HIPK3 HIPK3 RPS6KA5 RPS6KA5 PRKD1 PRKD1 MAP3K10 MAP3K10 MAP4K1 MAP4K1 AKT2 AKT2 TBK1 TBK1 CDK2 CDK2 MAP3K12 MAP3K12 VRK1 VRK1 RPS6KA1 RPS6KA1 SRPK2 SRPK2 HIPK2 HIPK2 NTRK2 NTRK2 MKNK2 MKNK2 CDC7 CDC7 AKT1 AKT1 MARK3 MARK3 PLK2 PLK2 MAST4 MAST4 TLK2 TLK2 ERN1 ERN1 STK38L STK38L AURKC AURKC LOC103011144 LOC103011144 PINK1 PINK1 RPS6KA3 RPS6KA3 PRKCD PRKCD RPS6KA4 RPS6KA4 TNKS TNKS PRPF4B PRPF4B STK32C STK32C LOC103005053 LOC103005053 ATM ATM ILK ILK MAST1 MAST1 UHMK1 UHMK1 PAK2 PAK2 MAPKAPK2 MAPKAPK2 RPS6KB2 RPS6KB2 MAPKAPK5 MAPKAPK5 GRK2 GRK2 CHEK2 CHEK2 CDK1 CDK1 DYRK4 DYRK4 MTOR MTOR WNK1 WNK1 HIPK1 HIPK1 MAPK9 MAPK9 MAP2K2 MAP2K2 MAPKAPK3 MAPKAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMKVcaM kinase-like vesicle-associated protein. (504 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (410 aa)
PRKD2Serine/threonine-protein kinase D2. (1023 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
TTKLOW QUALITY PROTEIN: dual specificity protein kinase TTK. (858 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D isoform X1; Belongs to the protein kinase superfamily. (385 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC103000311Histone H3; Belongs to the histone H3 family. (136 aa)
NEK7Serine/threonine-protein kinase Nek7 isoform X1; Belongs to the protein kinase superfamily. (336 aa)
HIPK4Homeodomain-interacting protein kinase 4. (612 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (344 aa)
CSNK1G1Casein kinase I; Belongs to the protein kinase superfamily. (466 aa)
CDK5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (459 aa)
MAST2Microtubule-associated serine/threonine-protein kinase 2 isoform X9. (1753 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
LATS2Serine/threonine-protein kinase LATS2. (795 aa)
CAMK1GCalcium/calmodulin-dependent protein kinase type 1G; Belongs to the protein kinase superfamily. (476 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
MYO3Amyosin-IIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1620 aa)
MAPK12Mitogen-activated protein kinase 12. (337 aa)
PRKCZProtein kinase C zeta type isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (518 aa)
LOC114238459Histone H3.3-like. (127 aa)
SBK1Serine/threonine-protein kinase SBK1. (318 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
PNCKCalcium/calmodulin-dependent protein kinase type 1B. (326 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase. (566 aa)
MYO3Bmyosin-IIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1238 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (765 aa)
PKD1LOW QUALITY PROTEIN: polycystin-1. (4200 aa)
TSSK4Testis-specific serine/threonine-protein kinase 4 isoform X1. (339 aa)
DYRK1BDual specificity tyrosine-phosphorylation-regulated kinase 1B. (513 aa)
CSNK1G2Casein kinase I. (310 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (779 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (674 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX isoform X1. (279 aa)
TTBK2Tau-tubulin kinase 2 isoform X1. (1283 aa)
PRKDCLOW QUALITY PROTEIN: DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4151 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X1. (887 aa)
MAPK13Mitogen-activated protein kinase. (288 aa)
LOC103006613LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 3-like. (590 aa)
SMTNL1Smoothelin-like protein 1. (441 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (963 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
ULK3Serine/threonine-protein kinase ULK3 isoform X1; Belongs to the protein kinase superfamily. (472 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
LATS1Serine/threonine-protein kinase LATS1. (1127 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
GAS6Growth arrest-specific protein 6. (540 aa)
TSSK1BTestis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (367 aa)
MAPK1Mitogen-activated protein kinase 1. (263 aa)
TSSK6Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa)
MAST3Microtubule-associated serine/threonine-protein kinase 3 isoform X1. (1327 aa)
LOC103010562Histone H3; Belongs to the histone H3 family. (136 aa)
DYRK3Dual specificity tyrosine-phosphorylation-regulated kinase 3. (587 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (752 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1. (528 aa)
LOC102999798Mitogen-activated protein kinase. (203 aa)
NEK6Serine/threonine-protein kinase Nek6 isoform X1; Belongs to the protein kinase superfamily. (365 aa)
PKN3Serine/threonine-protein kinase N3 isoform X1. (889 aa)
STK32ASerine/threonine-protein kinase 32A isoform X1; Belongs to the protein kinase superfamily. (395 aa)
TTBK1Tau-tubulin kinase 1. (1279 aa)
DCLK1Serine/threonine-protein kinase DCLK1 isoform X1. (741 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
SYKTyrosine-protein kinase. (626 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (691 aa)
STK4Serine/threonine-protein kinase 4. (411 aa)
LOC103001540Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
CAMK1Calcium/calmodulin-dependent protein kinase type 1; Belongs to the protein kinase superfamily. (370 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV isoform X1; Belongs to the protein kinase superfamily. (473 aa)
PRKAA1Non-specific serine/threonine protein kinase. (458 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
DCLK3Serine/threonine-protein kinase DCLK3. (845 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
LOC103002887Ribosomal protein S6 kinase alpha-6-like; Belongs to the protein kinase superfamily. (236 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
STK32BSerine/threonine-protein kinase 32B isoform X1; Belongs to the protein kinase superfamily. (414 aa)
CLK1Dual specificity protein kinase CLK1 isoform X1; Belongs to the protein kinase superfamily. (485 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
VRK2Serine/threonine-protein kinase VRK2. (512 aa)
LOC103005963Casein kinase I isoform X3; Belongs to the protein kinase superfamily. (416 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
CSNK1A1Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (368 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3646 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2645 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X1. (1497 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
CSNK1DCasein kinase I isoform X1. (371 aa)
PRKCANon-specific serine/threonine protein kinase. (559 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
LOC103003704Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
VRK3Inactive serine/threonine-protein kinase VRK3 isoform X1. (455 aa)
CAB39Calcium-binding protein 39. (341 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3. (763 aa)
MORC3MORC family CW-type zinc finger protein 3. (933 aa)
TLK1Serine/threonine-protein kinase tousled-like 1 isoform X1. (766 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
CLSPNLOW QUALITY PROTEIN: claspin. (1336 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (983 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
DGKQDiacylglycerol kinase. (938 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (531 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SBK2Serine/threonine-protein kinase SBK2; Belongs to the protein kinase superfamily. (348 aa)
ULK1Serine/threonine-protein kinase ULK1. (873 aa)
HIPK3Homeodomain-interacting protein kinase 3 isoform X1. (1214 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (645 aa)
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TBK1Serine/threonine-protein kinase TBK1. (753 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
VRK1Serine/threonine-protein kinase VRK1 isoform X1; Belongs to the protein kinase superfamily. (398 aa)
RPS6KA1Non-specific serine/threonine protein kinase. (700 aa)
SRPK2SRSF protein kinase 2 isoform X1. (717 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1207 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (463 aa)
CDC7LOW QUALITY PROTEIN: cell division cycle 7-related protein kinase. (580 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
MARK3Non-specific serine/threonine protein kinase. (701 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
MAST4LOW QUALITY PROTEIN: microtubule-associated serine/threonine-protein kinase 4. (2486 aa)
TLK2Serine/threonine-protein kinase tousled-like 2. (726 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (960 aa)
STK38LNon-specific serine/threonine protein kinase. (347 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (282 aa)
LOC103011144Histone H3.3-like. (136 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (405 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (712 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (601 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog isoform X1. (1041 aa)
STK32CSerine/threonine-protein kinase 32C isoform X3. (370 aa)
LOC103005053Non-specific serine/threonine protein kinase. (551 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
ILKIntegrin-linked protein kinase. (452 aa)
MAST1Microtubule-associated serine/threonine-protein kinase 1. (1499 aa)
UHMK1Serine/threonine-protein kinase Kist. (419 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (388 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (590 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (473 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
CHEK2Serine/threonine-protein kinase Chk2. (544 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
DYRK4Dual specificity tyrosine-phosphorylation-regulated kinase 4. (759 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
WNK1Serine/threonine-protein kinase WNK1. (2371 aa)
HIPK1Homeodomain-interacting protein kinase 1. (1211 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (303 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (436 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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