37 items (Balaenoptera acutorostrata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAL1	T-cell acute lymphocytic leukemia protein 1. (172 aa)
	PTCH1	LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
	GBX1	Homeobox protein GBX-1. (280 aa)
	SHH	LOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
	GSX2	GS homeobox 2. (299 aa)
	ASCL1	Achaete-scute homolog 1. (169 aa)
	GSX1	GS homeobox 1. (256 aa)
	PHOX2A	Paired mesoderm homeobox protein 2A. (218 aa)
	DBX1	Homeobox protein DBX1. (349 aa)
	ABT1	Activator of basal transcription 1. (275 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	HOXC10	Homeobox protein Hox-C10 isoform X1. (368 aa)
	FOXN4	Forkhead box protein N4. (518 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	DMRT3	Doublesex- and mab-3-related transcription factor 3. (506 aa)
	TBX20	T-box transcription factor TBX20. (449 aa)
	OLIG2	Oligodendrocyte transcription factor 2. (254 aa)
	SUFU	Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
	LBX1	Transcription factor LBX1. (282 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1591 aa)
	LHX4	LIM/homeobox protein Lhx4. (390 aa)
	CLN8	Protein CLN8. (284 aa)
	TCTN1	Tectonic-1 isoform X1. (588 aa)
	LHX1	LIM/homeobox protein Lhx1. (406 aa)
	HOXD10	Homeobox protein Hox-D10. (343 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (281 aa)
	NKX2-2	Homeobox protein Nkx-2.2. (273 aa)
	LHX3	LIM/homeobox protein Lhx3. (493 aa)
	ISL1	Insulin gene enhancer protein ISL-1. (349 aa)
	SOX4	Transcription factor SOX-4. (197 aa)
	ISL2	Insulin gene enhancer protein ISL-2. (359 aa)
	SCYL3	Protein-associating with the carboxyl-terminal domain of ezrin isoform X1. (742 aa)
	LHX5	LIM/homeobox protein Lhx5. (404 aa)
	SCYL1	N-terminal kinase-like protein isoform X1. (807 aa)
	DRAXIN	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	SOX13	Transcription factor SOX-13 isoform X1. (618 aa)

Your Current Organism:

Balaenoptera acutorostrata

NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	FOXN4	A0A383YTI0	A0A383ZYF3	Achaete-scute homolog 1.	Forkhead box protein N4.	0.629
ASCL1	GSX1	A0A383YTI0	A0A383YNC3	Achaete-scute homolog 1.	GS homeobox 1.	0.634
ASCL1	GSX2	A0A383YTI0	A0A383Z076	Achaete-scute homolog 1.	GS homeobox 2.	0.761
ASCL1	ISL1	A0A383YTI0	A0A384B7J6	Achaete-scute homolog 1.	Insulin gene enhancer protein ISL-1.	0.590
ASCL1	ISL2	A0A383YTI0	A0A383ZEI7	Achaete-scute homolog 1.	Insulin gene enhancer protein ISL-2.	0.471
ASCL1	LHX1	A0A383YTI0	A0A384ASD1	Achaete-scute homolog 1.	LIM/homeobox protein Lhx1.	0.424
ASCL1	LHX3	A0A383YTI0	A0A384B530	Achaete-scute homolog 1.	LIM/homeobox protein Lhx3.	0.451
ASCL1	NKX2-2	A0A383YTI0	A0A384AXE8	Achaete-scute homolog 1.	Homeobox protein Nkx-2.2.	0.476
ASCL1	OLIG2	A0A383YTI0	A0A384A9I6	Achaete-scute homolog 1.	Oligodendrocyte transcription factor 2.	0.767
ASCL1	PHOX2A	A0A383YTI0	A0A383ZF74	Achaete-scute homolog 1.	Paired mesoderm homeobox protein 2A.	0.626
ASCL1	SHH	A0A383YTI0	A0A452CFB9	Achaete-scute homolog 1.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.527
ASCL1	SOX4	A0A383YTI0	A0A384BC17	Achaete-scute homolog 1.	Transcription factor SOX-4.	0.439
DBX1	LHX1	A0A383ZIF1	A0A384ASD1	Homeobox protein DBX1.	LIM/homeobox protein Lhx1.	0.402
DBX1	LHX5	A0A383ZIF1	A0A383Z8C5	Homeobox protein DBX1.	LIM/homeobox protein Lhx5.	0.488
DBX1	OLIG2	A0A383ZIF1	A0A384A9I6	Homeobox protein DBX1.	Oligodendrocyte transcription factor 2.	0.518
DBX1	OLIG3	A0A383ZIF1	A0A384AVM0	Homeobox protein DBX1.	Oligodendrocyte transcription factor 3.	0.545
DBX1	SHH	A0A383ZIF1	A0A452CFB9	Homeobox protein DBX1.	LOW QUALITY PROTEIN: sonic hedgehog protein.	0.595
DLL4	FOXN4	A0A383ZZS4	A0A383ZYF3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Forkhead box protein N4.	0.633
DMRT3	GLI3	A0A384A4V2	A0A384AKQ7	Doublesex- and mab-3-related transcription factor 3.	Transcriptional activator GLI3 isoform X1.	0.406
DMRT3	GSX2	A0A384A4V2	A0A383Z076	Doublesex- and mab-3-related transcription factor 3.	GS homeobox 2.	0.441