STRINGSTRING
CLN8 CLN8 LHX4 LHX4 GLI3 GLI3 LBX1 LBX1 SUFU SUFU OLIG2 OLIG2 DMRT3 DMRT3 TBX20 TBX20 PAX6 PAX6 DLL4 DLL4 FOXN4 FOXN4 HOXC10 HOXC10 ABT1 ABT1 DBX1 DBX1 PHOX2A PHOX2A ISL2 ISL2 SCYL3 SCYL3 SCYL1 SCYL1 ASCL1 ASCL1 VLDLR VLDLR SHH SHH GBX1 GBX1 RELN RELN PTCH1 PTCH1 DAB1 DAB1 LRP8 LRP8 SOX4 SOX4 ISL1 ISL1 LHX3 LHX3 NKX2-2 NKX2-2 OLIG3 OLIG3 HOXD10 HOXD10 LHX1 LHX1 VSTM5 VSTM5 TCTN1 TCTN1 DCTN1 DCTN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLN8Protein CLN8. (284 aa)
LHX4LIM/homeobox protein Lhx4. (390 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1591 aa)
LBX1Transcription factor LBX1. (282 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
OLIG2Oligodendrocyte transcription factor 2. (254 aa)
DMRT3Doublesex- and mab-3-related transcription factor 3. (506 aa)
TBX20T-box transcription factor TBX20. (449 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
FOXN4Forkhead box protein N4. (518 aa)
HOXC10Homeobox protein Hox-C10 isoform X1. (368 aa)
ABT1Activator of basal transcription 1. (275 aa)
DBX1Homeobox protein DBX1. (349 aa)
PHOX2APaired mesoderm homeobox protein 2A. (218 aa)
ISL2Insulin gene enhancer protein ISL-2. (359 aa)
SCYL3Protein-associating with the carboxyl-terminal domain of ezrin isoform X1. (742 aa)
SCYL1N-terminal kinase-like protein isoform X1. (807 aa)
ASCL1Achaete-scute homolog 1. (169 aa)
VLDLRVery low-density lipoprotein receptor. (920 aa)
SHHLOW QUALITY PROTEIN: sonic hedgehog protein. (271 aa)
GBX1Homeobox protein GBX-1. (280 aa)
RELNReelin isoform X1. (3488 aa)
PTCH1LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
DAB1Disabled homolog 1. (588 aa)
LRP8Low-density lipoprotein receptor-related protein 8 isoform X1. (574 aa)
SOX4Transcription factor SOX-4. (197 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
LHX3LIM/homeobox protein Lhx3. (493 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
OLIG3Oligodendrocyte transcription factor 3. (281 aa)
HOXD10Homeobox protein Hox-D10. (343 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
VSTM5V-set and transmembrane domain-containing protein 5. (322 aa)
TCTN1Tectonic-1 isoform X1. (588 aa)
DCTN1Dynactin subunit 1 isoform X1. (1281 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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