STRINGSTRING
CCDC66 CCDC66 LOC114239234 LOC114239234 BIRC6 BIRC6 LOC103013777 LOC103013777 MYH10 MYH10 RAB11FIP4 RAB11FIP4 LOC114237079 LOC114237079 PTCH1 PTCH1 DCTN3 DCTN3 KLHL9 KLHL9 KLHL34 KLHL34 LOC103014251 LOC103014251 CYLD CYLD APC2 APC2 VPS4A VPS4A CUNH6orf89 CUNH6orf89 IST1 IST1 RNF8 RNF8 TXNDC9 TXNDC9 ECT2 ECT2 MITD1 MITD1 KATNA1 KATNA1 CHAMP1 CHAMP1 CHMP1B CHMP1B MTCL1 MTCL1 CTNND1 CTNND1 HEPACAM2 HEPACAM2 CCDC124 CCDC124 ANLN ANLN PRC1 PRC1 HSPA5 HSPA5 ENTR1 ENTR1 IQGAP1 IQGAP1 UVRAG UVRAG SPART SPART CENPC CENPC ARF6 ARF6 CEP44 CEP44 ARL8B ARL8B VPS4B VPS4B EXOC3 EXOC3 SPAST SPAST YPEL5 YPEL5 AGBL5 AGBL5 MAPRE3 MAPRE3 CEP126 CEP126 TBCK TBCK CRMP1 CRMP1 CENPE CENPE MICAL1 MICAL1 NEXMIF NEXMIF LOC103019709 LOC103019709 TEX14 TEX14 LYRM1 LYRM1 VPS37B VPS37B PPP1CC PPP1CC RAD21 RAD21 CCDC69 CCDC69 LOC102999029 LOC102999029 SVIL SVIL MPLKIP MPLKIP CEP55 CEP55 CPEB3 CPEB3 LZTS2 LZTS2 ARL3 ARL3 LOC103015993 LOC103015993 GNAI1 GNAI1 SEPT1 SEPT1 MAP11 MAP11 ALKBH4 ALKBH4 PLK1 PLK1 CHMP6 CHMP6 BIRC5 BIRC5 GDI1 GDI1 CHMP4C CHMP4C NUP62 NUP62 KIF4A KIF4A SEPT2 SEPT2 ERH ERH ZFYVE26 ZFYVE26 ANXA11 ANXA11 RAB8A RAB8A PKP4 PKP4 KLHDC8A KLHDC8A SSNA1 SSNA1 ARL8A ARL8A CDCA8 CDCA8 SEPT7 SEPT7 URB2 URB2 PKN2 PKN2 PKN1 PKN1 RAB11FIP3 RAB11FIP3 SEPT12 SEPT12 RALB RALB NAT10 NAT10 DCDC1 DCDC1 CHMP4A CHMP4A LOC103000833 LOC103000833 ZFYVE19 ZFYVE19 AGAP2 AGAP2 SIRT2 SIRT2 RACGAP1 RACGAP1 MICAL3 MICAL3 SEPT6 SEPT6 CLIC4 CLIC4 JTB JTB CHMP5 CHMP5 C9orf72 C9orf72 CENPF CENPF CAPG CAPG CHMP2A CHMP2A CHMP3 CHMP3 RCC2 RCC2 CDC42 CDC42 GNL3 GNL3 FLCN FLCN INCENP INCENP EML3 EML3 DTNBP1 DTNBP1 MAP10 MAP10 MAK MAK WIZ WIZ RACK1 RACK1 ABRAXAS2 ABRAXAS2 SH3GLB1 SH3GLB1 CTDP1 CTDP1 PIK3C3 PIK3C3 CHMP1A CHMP1A KIF20A KIF20A CDK1 CDK1 TTC28 TTC28 NUDC NUDC USP50 USP50 PIK3CB PIK3CB USP8 USP8 GNAI3 GNAI3 PSRC1 PSRC1 PIN1 PIN1 KEAP1 KEAP1 DNM2 DNM2 KLHDC8B KLHDC8B RHOA RHOA GNAI2 GNAI2 MARK4 MARK4 BCL3 BCL3 CHMP7 CHMP7 KIF14 KIF14 EML4 EML4 HNRNPU HNRNPU SCCPDH SCCPDH AURKB AURKB USP3 USP3 HSP90B1 HSP90B1 ANKRD54 ANKRD54 RASGEF1B RASGEF1B GEM GEM SLC2A1 SLC2A1 KATNAL1 KATNAL1 CHMP2B CHMP2B NEK2 NEK2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCDC66Coiled-coil domain-containing protein 66 isoform X1. (986 aa)
LOC114239234Leucine zipper putative tumor suppressor 2-like. (90 aa)
BIRC6LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6. (4861 aa)
LOC103013777LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 5-like. (227 aa)
MYH10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1886 aa)
RAB11FIP4Rab11 family-interacting protein 4. (558 aa)
LOC114237079Uncharacterized protein LOC114237079 isoform X1. (198 aa)
PTCH1LOW QUALITY PROTEIN: protein patched homolog 1. (1304 aa)
DCTN3Dynactin subunit 3 isoform X1. (199 aa)
KLHL9Kelch-like protein 9. (617 aa)
KLHL34LOW QUALITY PROTEIN: kelch-like protein 34. (666 aa)
LOC103014251LOW QUALITY PROTEIN: inner centromere protein-like. (810 aa)
CYLDLOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (953 aa)
APC2LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (1582 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (526 aa)
CUNH6orf89Bombesin receptor-activated protein C6orf89 homolog isoform X1. (361 aa)
IST1IST1 homolog isoform X1. (364 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (495 aa)
TXNDC9Thioredoxin domain-containing protein 9. (226 aa)
ECT2Protein ECT2 isoform X1. (914 aa)
MITD1MIT domain-containing protein 1. (249 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
CHAMP1Chromosome alignment-maintaining phosphoprotein 1. (815 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
MTCL1Microtubule cross-linking factor 1. (1488 aa)
CTNND1Catenin delta-1 isoform X1. (978 aa)
HEPACAM2HEPACAM family member 2 isoform X1. (481 aa)
CCDC124Coiled-coil domain-containing protein 124. (223 aa)
ANLNAnillin. (1092 aa)
PRC1Protein regulator of cytokinesis 1. (738 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
ENTR1Endosome-associated-trafficking regulator 1. (374 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1627 aa)
UVRAGUV radiation resistance-associated gene protein isoform X1. (709 aa)
SPARTSpartin isoform X1. (668 aa)
CENPCCentromere protein C. (943 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
CEP44Centrosomal protein of 44 kDa. (385 aa)
ARL8BADP-ribosylation factor-like protein 8B isoform X2; Belongs to the small GTPase superfamily. Arf family. (188 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
EXOC3Exocyst complex component 3. (745 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (530 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
AGBL5Cytosolic carboxypeptidase-like protein 5 isoform X1. (885 aa)
MAPRE3Microtubule-associated protein RP/EB family member 3 isoform X2. (281 aa)
CEP126Centrosomal protein of 126 kDa. (1088 aa)
TBCKTBC domain-containing protein kinase-like protein isoform X1. (893 aa)
CRMP1Dihydropyrimidinase-related protein 1. (509 aa)
CENPECentromere-associated protein E isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2709 aa)
MICAL1F-actin-monooxygenase MICAL1 isoform X1. (1085 aa)
NEXMIFNeurite extension and migration factor. (1515 aa)
LOC103019709Zinc finger FYVE domain-containing protein 26-like. (220 aa)
TEX14Inactive serine/threonine-protein kinase TEX14. (1372 aa)
LYRM1LYR motif-containing protein 1; Belongs to the complex I LYR family. (122 aa)
VPS37BVacuolar protein sorting-associated protein 37B. (219 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
RAD21Double-strand-break repair protein rad21 homolog isoform X1. (630 aa)
CCDC69Coiled-coil domain-containing protein 69. (353 aa)
LOC102999029Nuclear pore glycoprotein p62-like. (277 aa)
SVILLOW QUALITY PROTEIN: supervillin. (2291 aa)
MPLKIPM-phase-specific PLK1-interacting protein. (179 aa)
CEP55Centrosomal protein of 55 kDa. (462 aa)
CPEB3Cytoplasmic polyadenylation element-binding protein 3. (390 aa)
LZTS2Leucine zipper putative tumor suppressor 2. (661 aa)
ARL3ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family. (182 aa)
LOC103015993Charged multivesicular body protein 1b-2. (199 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
SEPT1Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (408 aa)
MAP11Uncharacterized protein C7orf43 homolog. (571 aa)
ALKBH4Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4. (270 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
CHMP6Charged multivesicular body protein 6. (190 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (143 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (425 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
NUP62Nuclear pore glycoprotein p62. (516 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1219 aa)
SEPT2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
ERHEnhancer of rudimentary homolog; May have a role in the cell cycle. (104 aa)
ZFYVE26Zinc finger FYVE domain-containing protein 26 isoform X1. (2543 aa)
ANXA11Annexin. (503 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
PKP4Plakophilin-4 isoform X1. (1151 aa)
KLHDC8AKelch domain-containing protein 8A isoform X1. (350 aa)
SSNA1Sjoegren syndrome nuclear autoantigen 1. (119 aa)
ARL8AADP-ribosylation factor-like protein 8A; Belongs to the small GTPase superfamily. Arf family. (258 aa)
CDCA8Borealin. (280 aa)
SEPT7Septin-7 isoform X3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (437 aa)
URB2LOW QUALITY PROTEIN: unhealthy ribosome biogenesis protein 2 homolog. (1528 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (983 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
RAB11FIP3Rab11 family-interacting protein 3. (473 aa)
SEPT12Septin-12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (363 aa)
RALBRas-related protein Ral-B isoform X1. (163 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
DCDC1Doublecortin domain-containing protein 1. (1789 aa)
CHMP4ACharged multivesicular body protein 4a. (222 aa)
LOC103000833Magnesium-dependent phosphatase 1. (164 aa)
ZFYVE19abscission/NoCut checkpoint regulator isoform X3. (435 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (857 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
MICAL3LOW QUALITY PROTEIN: F-actin-monooxygenase MICAL3. (2095 aa)
SEPT6Septin-6 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (444 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (211 aa)
JTBProtein JTB. (146 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
C9orf72Guanine nucleotide exchange C9orf72 homolog. (481 aa)
CENPFCentromere protein F. (3077 aa)
CAPGMacrophage-capping protein. (349 aa)
CHMP2ACharged multivesicular body protein 2a isoform X1. (222 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
RCC2Protein RCC2. (575 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
GNL3Guanine nucleotide-binding protein-like 3. (547 aa)
FLCNFolliculin isoform X1. (579 aa)
INCENPInner centromere protein. (889 aa)
EML3Echinoderm microtubule-associated protein-like 3 isoform X1. (868 aa)
DTNBP1Dysbindin. (326 aa)
MAP10Microtubule-associated protein 10. (846 aa)
MAKSerine/threonine-protein kinase MAK isoform X1. (648 aa)
WIZProtein Wiz isoform X1. (1697 aa)
RACK1Receptor of activated protein C kinase 1 isoform X1. (317 aa)
ABRAXAS2BRISC complex subunit Abraxas 2. (424 aa)
SH3GLB1endophilin-B1 isoform X1. (402 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (765 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
CHMP1ACharged multivesicular body protein 1a. (267 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
TTC28LOW QUALITY PROTEIN: tetratricopeptide repeat protein 28. (2471 aa)
NUDCNuclear migration protein nudC. (331 aa)
USP50Inactive ubiquitin carboxyl-terminal hydrolase 50; Belongs to the peptidase C19 family. (373 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1087 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PSRC1Proline/serine-rich coiled-coil protein 1 isoform X1. (346 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (215 aa)
KEAP1Kelch-like ECH-associated protein 1. (624 aa)
DNM2Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (708 aa)
KLHDC8BKelch domain-containing protein 8B. (354 aa)
RHOATransforming protein RhoA. (193 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
MARK4Non-specific serine/threonine protein kinase. (713 aa)
BCL3B-cell lymphoma 3 protein. (492 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1640 aa)
EML4Echinoderm microtubule-associated protein-like 4 isoform X1. (1000 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (798 aa)
SCCPDHSaccharopine dehydrogenase-like oxidoreductase. (429 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (344 aa)
USP3Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (435 aa)
HSP90B1Endoplasmin. (805 aa)
ANKRD54Ankyrin repeat domain-containing protein 54 isoform X1. (299 aa)
RASGEF1Bras-GEF domain-containing family member 1B isoform X1. (479 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (480 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (514 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
NEK2Serine/threonine-protein kinase Nek2 isoform X1. (445 aa)
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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